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Membrane raft microdomains in chemokine receptor function
Seminars in Immunology, 2001Cell chemotaxis requires the acquisition and maintenance of both spatial and functional asymmetry between initially equivalent cell parts. In leukocytes one becomes the leading edge and the other, the rear edge or uropod. The acquisition of this cell polarity is controlled by an array of chemoattractants, including those of the chemokine family.
Emilia Mira+5 more
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The amplification of TCR signaling by dynamic membrane microdomains
Trends in Immunology, 2001Modulation of T-cell receptor (TCR) signaling is essential for the regulation of T-cell responses to infectious agents. Recently, many laboratories have suggested that TCR triggering might be compartmentalized in plasma membrane microdomains called rafts.
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Molecular composition of functional microdomains in bacterial membranes
Chemistry and Physics of Lipids, 2015Membranes of eukaryotic cells organize a number of proteins related to signal transduction and membrane trafficking into microdomains, which are enriched in particular lipids, like cholesterol and sphingolipids and are commonly referred as to lipid rafts or membrane rafts.
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