Results 231 to 240 of about 1,117,893 (276)
Revising NHE‐1: From Cardiac Homeostasis to Heart Failure and Future Drug Development
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT NHE‐1 is a Na+/H+ exchanger that receives phosphorylation signals, binds calmodulin and responds to neurohormonal input from angiotensin II, endothelin‐1, and adrenergic pathways. In cardiac myocytes, NHE‐1 maintains pH homeostasis and couples to Na+/Ca2+ exchange and mitochondrial ion handling. During heart disease sustained activation drives
Vasileios Bouratzis +8 more
wiley +1 more source
Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska +5 more
wiley +1 more source
Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu +5 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.Piezo1 functions as a context‐dependent mechanotransduction node linking mechanical cues to inflammation, tissue remodelling and metabolic regulation in digestive homeostasis and disease. In epithelial, immune, stromal and endocrine cells, Piezo1‐mediated Ca2+ signalling contributes to barrier and mucus homeostasis, epithelial renewal and repair ...
Yuan Xia +6 more
wiley +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 5, September 2026.Schematic illustration comparing the MD performance of pure PTFE NFMs and PTFE/PI NFMs. Polytetrafluoroethylene (PTFE) membranes are widely recognized for their low surface energy and strong resistance to salt accumulation in membrane distillation (MD) processes.
Yuan Liu +7 more
wiley +1 more source
The importance of membrane microdomains for bile salt-dependent biliary lipid secretion.
J Cell Sci, 2018 Eckstein J, Holzhütter HG, Berndt N.
europepmc +1 more source
Glia, Volume 74, Issue 9, September 2026.Dual‐color STORM resolves the precise architecture and protein distributions within hippocampal astrocytes at the nanoscale. Identification of a sparse but specific MAGL pool in CA1 astrocytic processes. Astrocytic MAGL is not synapse‐associated, suggesting a synapse‐independent role.
Miklós Zöldi, István Katona
wiley +1 more source
Dorso‐Ventral and Night‐Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes
Glia, Volume 74, Issue 9, September 2026.Hippocampal astrocytic K+ buffering varies by region and time. Ventral astrocytes show faster K+ accumulation due to reduced Kir4.1 function. Such regional divergence is modulated by circadian shifts in Kir4.1 and gap junction coupling. ABSTRACT Astrocytes regulate extracellular potassium (K+) through multiple mechanisms operating across distinct ...
Nariman Kiani +5 more
wiley +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.Neutrophils release extracellular vesicles (EVs) in response to Candida albicans, and these EVs bind to the fungus in a complement‐dependent manner while carrying neutrophil surface markers and antimicrobial proteins. Despite this cargo, EV coating does not inhibit fungal growth but markedly reduces neutrophil phagocytic uptake in purified‐cell assays ...
Jennifer J. Patitz +15 more
wiley +1 more source