Results 241 to 250 of about 34,175 (279)

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang, Gongsang Cuomu, Sang Jijia, Yumei Yang, Jufen Liu, Yumin Tao   +5 more
wiley   +1 more source

Atomic‐Level Insight of Carbon‐Based Anodes for Advanced Sodium Storage: Electrochemical Mechanisms and Molecular Simulation‐Assisted Modification

cMat, Volume 3, Issue 2, June 2026.
Hard carbon is a promising anode for sodium‐ion batteries, yet its Na+ storage mechanism remains elusive. This review summarizes Na+ storage behavior in hard carbon from first‐principles (DFT) calculations, establishes structure–function relationships, summarizes DFT‐based evaluation methods, and provides perspectives for the rational theoretical ...
Yuefang Chen, Guoping Liu, Yuwen Zhao, Mengmeng Zhang, Yifang Zhang, Zhenyang Yu, Zhijia Zhang, Huijun Li, Yong Jiang   +8 more
wiley   +1 more source

Favorable Systemic Immune‐Inflammation Status Enhances the Neuroprotective Effects of Butylphthalide in Ischemic Stroke: A Post Hoc Analysis of BAST Trial

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This post hoc analysis of the BAST trial demonstrates that favorable or improving systemic immune‐inflammation index (SII) status during the acute phase of ischemic stroke was associated with better 90‐day functional outcomes and lower vascular risk. Patients with persistently favorable SII who were assigned to butylphthalide showed the most favorable ...
Quan Zhou, Xue Tian, Xue Xia, Qin Xu, Meng Gao, Luwen Zhang, Anxin Wang   +6 more
wiley   +1 more source

Cardiovascular β‐Adrenergic Receptor Distribution and Function: Influence of Species, Sex, Age, and Tissue

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid, Irakli Kopaliani, Birgit Zatschler, Ansam Seif, Stephan Speier, Andreas Deussen   +5 more
wiley   +1 more source

Single‐cell profiling reveals peripheral blood immune landscape remodelling in breast cancer lymph node metastasis

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
scRNA‐seq reveals pro‐metastatic neutrophil and exhausted T/NK subsets in BC patients with LN metastasis. Interferon‐stimulated neutrophils secrete LGALS9, drives T/NK cell exhaustion via HAVCR2. Neutralising LGALS9 restores T‐cell anti‐tumour activity, suggesting a novel therapeutic target.
Bo Chen, Kang Ma, Yunjie Wang, Liulu Zhang, Xinyue Feng, Cheng Long, Xuejing Tan, Kun Wang   +7 more
wiley   +1 more source

A Pseudo‐Two‐Dimensional Reaction–Diffusion Model for Rational Design of Antibacterial–Antioxidant Ag–ZnO/Fucoidan Nanocomposites

Engineering Reports, Volume 8, Issue 6, June 2026.
A pseudo‐two‐dimensional (P2D) reaction–diffusion framework is proposed to model reactive oxygen species (ROS) generation, transport, and scavenging in Ag–ZnO/Fucoidan nanocomposites. Spatially segregated ROS source (Ag–ZnO) and sink (fucoidan) domains are embedded into a one‐dimensional computational model, capturing nonlinear feedback between site ...
Mohamed Abu Shuheil, Maryam Saleem Mohammed Ali, Roopashree R., Subhashree Ray, Baraa Mohammed Yaseen, Kavitha V., Renu Sharma, Aashna Sinha, Naser Aslanian   +8 more
wiley   +1 more source

Mechanistic Insights Into Color and Texture Stability of Frozen Tropical Vegetables: Processing, Modeling, and Preservation Strategies

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This review elucidates the mechanistic pathways governing color and texture degradation in frozen tropical vegetables, emphasizing pigment oxidation, enzymatic softening, and ice crystal‐induced structural damage. It integrates kinetic, Arrhenius, RSM, and machine‐learning models with advanced preservation strategies to optimize freezing processes ...
Muhammad Muntasir Mahmud, Md. Suhel Mia, Md. Hassan Bin Nabi, Abid Hassan Arnab, Wahidu Zzaman   +4 more
wiley   +1 more source

Artificial Sweeteners and Autoimmune Diseases: Insights From Integrative Bioinformatics and Mendelian Randomization

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study provides a novel molecular perspective on the role of AS in ADs development. We identified a positive association between artificially sweetened cereal intake and ADs risk and revealed multiple pathogenic mechanisms involving apoptosis, inflammatory signaling, immune activation, and gut microbiota dysbiosis.
Yupei Liu, Jizhen Huang, Xue Hu, Shan Tian, Jiao Li, Shiyun Tan, Weiguo Dong   +6 more
wiley   +1 more source

Sorting and membrane organization of GPI-anchored proteins in polarized epithelial cells

, 2008
Tivodar, Simona Sanda
core