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Eye &ENT Research, Volume 3, Issue 3, Page 186-189, September 2026.
Yiming Wu +6 more
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Update on lipid membrane microdomains
Lipid membrane microdomains are involved in major types of disease, ranging from vascular and metabolic diseases to neurodegeneration, autoimmunity, infectious and inflammatory diseases, and cancer. This review provides an update of membrane microdomain abnormalities.Lipid membrane microdomains are dynamic assemblies of sphingolipids, cholesterol and ...
Schmitz, Gerd, Grandl, Margot
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Membrane microdomains and caveolae
Current Opinion in Cell Biology, 1999Glycosphingolipid- and cholesterol-enriched microdomains, or rafts, within the plasma membrane of eukaryotic cells have been implicated in many important cellular processes, such as polarized sorting of apical membrane proteins in epithelial cells and signal transduction.
Kurzchalia, T. V., Parton, RG
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Proteomics of plasma membrane microdomains
Expert Review of Proteomics, 2005Plasma membrane microdomains represent subcompartments of the plasma membrane characterized by a specific lipid and protein composition. The recognition of microdomains in nearly all the eukaryotic membranes has accredited them with specialized functions in health and disease.
RAIMONDO, FRANCESCA +5 more
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Current Opinion in Cell Biology, 2002
Several lines of evidence indicate that the lipids in the plasma membrane of animal cells are inhomogeneously distributed, and that various types of specialized lipid domains play an important role in many biological processes. The characteristics of these domains, such as size, composition and dynamics, are currently under active investigation.
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Several lines of evidence indicate that the lipids in the plasma membrane of animal cells are inhomogeneously distributed, and that various types of specialized lipid domains play an important role in many biological processes. The characteristics of these domains, such as size, composition and dynamics, are currently under active investigation.
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Membrane microdomains and the regulation of HDL biogenesis
Current Opinion in Lipidology, 2018Purpose of review The major cardio-protective function of HDL is to remove excess cellular cholesterol in the process of HDL particle formation and maturation. The HDL biogenic procedure requiring protein–lipid interactions has been incompletely understood, and here we discuss recent progress and insights into the mechanism of ...
Jacques, Genest +2 more
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Budded membrane microdomains as tension regulators
Physical Review E, 2006We propose a mechanism by which changes of the mechanical tension of a composite lipid membrane are buffered by the invagination of membrane domains. We show that domain invagination, driven by differences in chemical composition, is a first-order transition controlled by membrane tension.
Pierre, Sens, Matthew S, Turner
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Isolation of Plasma Membrane and Plasma Membrane Microdomains
2016The plasma membrane surrounds the cytoplasm of a cell and functions as a barrier to separate the intracellular compartment from the extracellular environment. Protein and lipid components distribute nonuniformly and the components form clusters with various functions in the plasma membrane.
Anzu, Minami +3 more
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DETECTING MICRODOMAINS IN INTACT CELL MEMBRANES
Annual Review of Physical Chemistry, 2005▪ Abstract Current models for cellular plasma membranes focus on spatial heterogeneity and how this heterogeneity relates to cell function. In particular, putative lipid raft membrane domains have been postulated to exist based in large part on the results that a significant fraction of the membrane is detergent insoluble and that molecules ...
B Christoffer, Lagerholm +3 more
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