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Chloride Homeostasis Failure in Human Disease: KCC2/NKCC1 Microdomain Dysfunction as a Driver of Cortical Network Collapse. [PDF]
Int J Mol SciDumitrescu D +5 more
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PROTEOMICS, 2006
AbstractBiological membranes are compartmentalized into microdomains that exhibit particular lipid and protein compositions. Membrane microdomains, such as tetraspanin‐enriched microdomains and lipid rafts, have been suggested to play a role in a variety of physiological and pathological processes.
François, Le Naour +3 more
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AbstractBiological membranes are compartmentalized into microdomains that exhibit particular lipid and protein compositions. Membrane microdomains, such as tetraspanin‐enriched microdomains and lipid rafts, have been suggested to play a role in a variety of physiological and pathological processes.
François, Le Naour +3 more
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Membrane microdomains and caveolae
Current Opinion in Cell Biology, 1999Glycosphingolipid- and cholesterol-enriched microdomains, or rafts, within the plasma membrane of eukaryotic cells have been implicated in many important cellular processes, such as polarized sorting of apical membrane proteins in epithelial cells and signal transduction.
Kurzchalia, T. V., Parton, RG
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Update on lipid membrane microdomains
Current Opinion in Clinical Nutrition and Metabolic Care, 2008Lipid membrane microdomains are involved in major types of disease, ranging from vascular and metabolic diseases to neurodegeneration, autoimmunity, infectious and inflammatory diseases, and cancer. This review provides an update of membrane microdomain abnormalities.Lipid membrane microdomains are dynamic assemblies of sphingolipids, cholesterol and ...
Schmitz, Gerd, Grandl, Margot
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Proteomics of plasma membrane microdomains
Expert Review of Proteomics, 2005Plasma membrane microdomains represent subcompartments of the plasma membrane characterized by a specific lipid and protein composition. The recognition of microdomains in nearly all the eukaryotic membranes has accredited them with specialized functions in health and disease.
RAIMONDO, FRANCESCA +5 more
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Current Opinion in Cell Biology, 2002
Several lines of evidence indicate that the lipids in the plasma membrane of animal cells are inhomogeneously distributed, and that various types of specialized lipid domains play an important role in many biological processes. The characteristics of these domains, such as size, composition and dynamics, are currently under active investigation.
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Several lines of evidence indicate that the lipids in the plasma membrane of animal cells are inhomogeneously distributed, and that various types of specialized lipid domains play an important role in many biological processes. The characteristics of these domains, such as size, composition and dynamics, are currently under active investigation.
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DETECTING MICRODOMAINS IN INTACT CELL MEMBRANES
Annual Review of Physical Chemistry, 2005▪ Abstract Current models for cellular plasma membranes focus on spatial heterogeneity and how this heterogeneity relates to cell function. In particular, putative lipid raft membrane domains have been postulated to exist based in large part on the results that a significant fraction of the membrane is detergent insoluble and that molecules ...
B Christoffer, Lagerholm +3 more
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Lipid microdomains – plant membranes get organized
Trends in Plant Science, 2005The plant plasma membrane is now known to be a more sophisticated structure than was previously thought. Sebastien Mongrand et al. and Georg Borner et al. have isolated specific plasma membrane microdomains ('lipid rafts') that are enriched in sterols and sphingolipids.
Stephen W, Martin +2 more
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Budded membrane microdomains as tension regulators
Physical Review E, 2006We propose a mechanism by which changes of the mechanical tension of a composite lipid membrane are buffered by the invagination of membrane domains. We show that domain invagination, driven by differences in chemical composition, is a first-order transition controlled by membrane tension.
Pierre, Sens, Matthew S, Turner
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