Results 61 to 70 of about 58,466 (172)

Lck, membrane microdomains and TCR triggering machinery: defining the new rules of engagement

Frontiers in Immunology, 2012
In spite of a comprehensive understanding of the schematics of T cell receptor (TCR) signaling, the mechanisms regulating compartmentalization of signaling molecules, their transient interactions and rearrangement of membrane structures initiated upon ...
Dominik eFilipp, Ondřej eBallek, Jasper eManning   +2 more
doaj   +1 more source

The organisation and functions of local Ca²⁺ signals [PDF]

, 2001
Calcium (Ca2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation.
Berridge, Michael J., Bootman, Martin D., Lipp, Peter   +2 more
core  

A novel biotinylated lipid raft reporter for electron microscopic imaging of plasma membrane microdomains

Journal of Lipid Research, 2012
The submicroscopic spatial organization of cell surface receptors and plasma membrane signaling molecules is readily characterized by electron microscopy (EM) via immunogold labeling of plasma membrane sheets.
Kimberly J. Krager, Mitul Sarkar, Erik C. Twait, Nancy L. Lill, John G. Koland   +4 more
doaj   +1 more source

Raft microdomain localized in the luminal leaflet of inner membrane complex of living Toxoplasma gondii

European Journal of Cell Biology, 2021
Membrane microdomains or rafts, sterol- and sphingolipid-rich microdomains in the plasma membrane have been studied extensively in mammalian cells. Recently, rafts were found to mediate virulence in a variety of parasites, including Toxoplasma gondii ...
Rikako Konishi, Yuna Kurokawa, Kanna Tomioku, Tatsunori Masatani, Xuenan Xuan, Akikazu Fujita   +5 more
doaj   +1 more source

Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains

Retrovirology, 2007
Background The Nef protein of Human Immunodeficiency Viruses optimizes viral spread in the infected host by manipulating cellular transport and signal transduction machineries.
Geyer Matthias, Breuer Sebastian, Glass Bärbel, Leibrecht Iris, Rauch Susanne, Munte Claudia E, Tibroni Nadine, Krautkrämer Ellen, Brügger Britta, Kräusslich Hans-Georg, Kalbitzer Hans, Wieland Felix T, Fackler Oliver T   +12 more
doaj   +1 more source

Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies [PDF]

, 2013
Clostridium perfringens epsilon toxin (Etx) is a pore-forming toxin responsible for a severe and rapidly fatal enterotoxemia of ruminants. The toxin is classified as a category B bioterrorism agent by the U.S.
Abe, Abrami, Bhown, Bokori-Brown, Chassin, Cole, Davis, De Colibus, Diep, Dorca-Arevalo, Emsley, Finnie, Ivie, Ivie, Jin, Knight, Lavinder, Lonchamp, McClain, McCoy, McDonel, Minami, Miyamoto, Miyamoto, Miyata, Murshudov, Nagahama, Nagahama, Nagahama, Oyston, Parker, Payne, Pelish, Petit, Pflugrath, Popoff, Popoff, Recommendations of the CDC Strategic Planning Workgroup, Songer, Uzal, Winn   +40 more
core   +1 more source

Receptor Tyrosine Kinases — Expanding Horizons

Cells, 2014
This Special Issue of Cells on receptor tyrosine kinases (RTKs) is a timely and unique assemblage of scholarly insights into topics that have relatively recently entered the spotlight in relation to this class of molecules. The review by Julien et al. [1]
Sassan Hafizi
doaj   +1 more source

Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels [PDF]

, 2005
The relationship between receptor-induced membrane phosphatidylinositol-4'5'-bisphosphate (PIP2) hydrolysis and M-current inhibition was assessed in single-dissociated rat sympathetic neurons by simultaneous or parallel recording of membrane current and ...
Abogadie, FC, Brown, DA, Filippov, AK, Hughes, S, Marsh, SJ, Tatulian, L, Winks, JS   +6 more
core   +1 more source

Cholesterol-Dependent γ-Secretase Activity in Buoyant Cholesterol-Rich Membrane Microdomains

Neurobiology of Disease, 2002
Buoyant membrane fractions containing presenilin 1 (PS1), an essential component of the γ-secretase complex, and APP CTFβ, a γ-secretase substrate, can be isolated from cultured cells and brain by several different fractionation procedures that are ...
Suzanne Wahrle, Pritam Das, Andrew C. Nyborg, Chris McLendon, Mikio Shoji, Takeshi Kawarabayashi, Linda H. Younkin, Steven G. Younkin, Todd E. Golde   +8 more
doaj   +1 more source

A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites. [PDF]

, 2019
Interactions between epithelial cells and neurons influence a range of sensory modalities including taste, touch, and smell. Vertebrate and invertebrate epidermal cells ensheath peripheral arbors of somatosensory neurons, including nociceptors, yet the ...
Clanton, Joshua A, Cronan, Mark R, Jiang, Nan, Kim, Hyeon-Jin, Luedke, Kory P, Parker, Edward D, Parrish, Jay Z, Rasmussen, Jeffrey P, Rosenberg, Marci F, Sagasti, Alvaro, Vaughan, Joshua C   +10 more
core