Results 51 to 60 of about 1,117,893 (276)

The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif

Biology Open, 2013
Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains.
Peter G. Billcliff, Oforiwa A. Gorleku, Luke H. Chamberlain, George Banting   +3 more
doaj   +1 more source

Lipid Rafts and Plant Gravisensitivity

Life, 2022
The necessity to include plants as a component of a Bioregenerative Life Support System leads to investigations to optimize plant growth facilities as well as a better understanding of the plant cell membrane and its numerous activities in the signaling,
Elizabeth L. Kordyum, Olga A. Artemenko, Karl H. Hasenstein   +2 more
doaj   +1 more source

Analysis of lipid-composition changes in plasma membrane microdomains[S]

Journal of Lipid Research, 2015
Sphingolipids accumulate in plasma membrane microdomain sites, such as caveolae or lipid rafts. Such microdomains are considered to be important nexuses for signal transduction, although changes in the microdomain lipid components brought about by ...
Hideo Ogiso, Makoto Taniguchi, Toshiro Okazaki   +2 more
doaj   +1 more source

Tracking microdomain dynamics in cell membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009
Studies of the diffusion of proteins and lipids in the plasma membrane of cells have long pointed to the presence of membrane domains. A major challenge in the field of membrane biology has been to characterize the various cellular structures and mechanisms that impede free diffusion in cell membranes and determine the consequences that membrane ...
Day, Charles A., Kenworthy, Anne K.
openaire   +2 more sources

Role of Membrane Microdomains in Compartmentation of cAMP Signaling [PDF]

PLoS ONE, 2014
Spatially restricting cAMP production to discrete subcellular locations permits selective regulation of specific functional responses. But exactly where and how cAMP signaling is confined is not fully understood. Different receptors and adenylyl cyclase isoforms responsible for cAMP production are not uniformly distributed between lipid raft and non ...
Agarwal, Shailesh R, Yang, Pei-Chi, Rice, Monica, Singer, Cherie A, Nikolaev, Viacheslav O, Lohse, Martin J, Clancy, Colleen E, Harvey, Robert D   +7 more
openaire   +7 more sources

Tetraspanin-enriched microdomains: The building blocks of migrasomes

Cell Insight, 2022
The migrasome is a newly discovered organelle of migrating cells. Migrasomes play diverse physiological roles including mitochondrial quality control, lateral transfer of material between cells, and delivery of signaling molecules to spatially defined ...
Yuwei Huang, Li Yu
doaj   +1 more source

Endothelial Cell Behavior Is Determined by Receptor Clustering Induced by Thrombospondin-1

Frontiers in Cell and Developmental Biology, 2021
The thrombospondins (TSPs) are a family of multimeric extracellular matrix proteins that dynamically regulate cellular behavior and response to stimuli.
Verônica Morandi, Jim Petrik, Jack Lawler   +2 more
doaj   +1 more source

The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect [PDF]

, 2006
Receptor-mediated internalization to the endoplasmic reticulum (ER) and subsequent retro-translocation to the cytosol are essential sequential processes required for the productive intoxication of susceptible mammalian cells by Shiga-like toxin-1 (SLTx).
Falguières, T, Platt, Frances M., Platt, Frances, Roberts, LM, Sillence, DJ, Smith, Daniel C., Jarvis, Rosemary M., Lord, JM, Smith, DC, Lord, J. Michael, Roberts, Lynne M., Jarvis, R. M., Sillence, Daniel J., Johannes, Ludger, Falguires, T., Falguières, Thomas, Lord, Mike, Johannes, L, Roberts, L. M. (Lynne M.), Jarvis, RM, Smith, D. C.   +20 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine

Frontiers in Cell and Developmental Biology, 2020
Cytokinesis is the last step of cell division that partitions the cellular organelles and cytoplasm of one cell into two. In animal cells, cytokinesis requires Rho-GTPase-dependent assembly of F-actin and myosin II (actomyosin) to form an equatorial ...
Sabrya C. Carim, Amel Kechad, Gilles R. X. Hickson, Gilles R. X. Hickson   +3 more
doaj   +1 more source