Results 51 to 60 of about 34,175 (279)
Scientific Reports, 2021 Lipid rafts, sterol-rich and sphingolipid-rich microdomains on the plasma membrane are important in processes like cell signaling, adhesion, and protein and lipid transport.
Shiomi Koudatsu +8 more
doaj +1 more source
Caveolin is present in intestinal cells: role in cholesterol trafficking?
Journal of Lipid Research, 1998 It was postulated that specialized microdomains of the plasma membrane, consistent with caveolae, might play a role in cholesterol trafficking in intestinal cells.
F. Jeffrey Field +3 more
doaj +1 more source
The role of type 4 phosphodiesterases in generating microdomains of cAMP: Large scale stochastic simulations [PDF]
, 2010 Cyclic AMP (cAMP) and its main effector Protein Kinase A (PKA) are critical for several aspects of neuronal function including synaptic plasticity. Specificity of synaptic plasticity requires that cAMP activates PKA in a highly localized manner despite ...
Terrin, A. +35 more
core +1 more source
Membrane Microdomains and Vascular Biology [PDF]
Circulation, 2003 The classic model of cell plasma membrane organization is that of a uniform, fluid environment in which protein and lipid constituents diffuse rapidly in an unrestricted fashion. Recent experimental evidence, however, reveals a far more complex membrane organization consisting of microdomains assembled from lipid constituents that have distinct ...
R Preston, Mason, Robert F, Jacob
openaire +2 more sources
Steric exclusion and protein conformation determine the localization of plasma membrane transporters
Nature Communications, 2018 The yeast plasma membrane consists of membrane microdomains with distinct protein composition. Here the authors use high-resolution single molecule imaging to observe diffusion of specific transmembrane proteins in and out of these microdomains, and ...
Frans Bianchi +9 more
doaj +1 more source
The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif
Biology Open, 2013 Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains.
Peter G. Billcliff +3 more
doaj +1 more source
Lipid Rafts and Plant Gravisensitivity
Life, 2022 The necessity to include plants as a component of a Bioregenerative Life Support System leads to investigations to optimize plant growth facilities as well as a better understanding of the plant cell membrane and its numerous activities in the signaling,
Elizabeth L. Kordyum +2 more
doaj +1 more source
Analysis of lipid-composition changes in plasma membrane microdomains[S]
Journal of Lipid Research, 2015 Sphingolipids accumulate in plasma membrane microdomain sites, such as caveolae or lipid rafts. Such microdomains are considered to be important nexuses for signal transduction, although changes in the microdomain lipid components brought about by ...
Hideo Ogiso +2 more
doaj +1 more source
Tetraspanin-enriched microdomains: The building blocks of migrasomes
Cell Insight, 2022 The migrasome is a newly discovered organelle of migrating cells. Migrasomes play diverse physiological roles including mitochondrial quality control, lateral transfer of material between cells, and delivery of signaling molecules to spatially defined ...
Yuwei Huang, Li Yu
doaj +1 more source
Tracking microdomain dynamics in cell membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009 Studies of the diffusion of proteins and lipids in the plasma membrane of cells have long pointed to the presence of membrane domains. A major challenge in the field of membrane biology has been to characterize the various cellular structures and mechanisms that impede free diffusion in cell membranes and determine the consequences that membrane ...
Day, Charles A., Kenworthy, Anne K.
openaire +2 more sources