Results 51 to 60 of about 56,803 (290)

Plasma membrane microdomains in aging and disease [PDF]

Geriatrics & Gerontology International, 2010
The plasma membrane of eukaryotic cells participates in signal transduction and many other cellular events to maintain the physiological state of cells. In recent decades, much attention has been paid to membrane microdomains, called lipid rafts or membrane rafts, as signaling platforms in the plasma membrane.
Yoshiko, Ohno-Iwashita, Yukiko, Shimada, Masami, Hayashi, Mitsushi, Inomata   +3 more
openaire   +2 more sources

Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine

Frontiers in Cell and Developmental Biology, 2020
Cytokinesis is the last step of cell division that partitions the cellular organelles and cytoplasm of one cell into two. In animal cells, cytokinesis requires Rho-GTPase-dependent assembly of F-actin and myosin II (actomyosin) to form an equatorial ...
Sabrya C. Carim, Amel Kechad, Gilles R. X. Hickson, Gilles R. X. Hickson   +3 more
doaj   +1 more source

Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe

mBio, 2021
Cholesterol influences membrane fluidity and forms membrane microdomains called lipid rafts that serve as organizing centers for the assembly of signaling molecules. Flotillin (FLOT) is a cholesterol-binding lipid-raft protein.
Weiyan Huang, Qingming Xiong, Mingqun Lin, Yasuko Rikihisa   +3 more
doaj   +1 more source

Theory of microphase separation in bidisperse chiral membranes

, 2016
We present a Ginzburg-Landau theory of micro phase separation in a bidisperse chiral membrane consisting of rods of opposite handendness. This model system undergoes a phase transition from an equilibrium state where the two components are completely ...
Baskaran, Aparna, Baskaran, Arvind, Chakraborty, Bulbul, Hagan, Michael F., Sakhardande, Raunak, Stanojeviea, Stefan   +5 more
core   +1 more source

Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution. [PDF]

, 2017
Thy-1-negative lung fibroblasts are resistant to apoptosis. The mechanisms governing this process and its relevance to fibrotic remodeling remain poorly understood. By using either sorted or transfected lung fibroblasts, we found that Thy-1 expression is
Bradley, John E, Espinoza, Celia R, Finley, J Cameron, Hagood, James S, Head, Brian P, Kim, Jeeyeon, Liu, Xiaoqiu, Mah, Emma J, Patel, Hemal H, Shentu, Tzu-Pin, Taype, Carmen A, Wong, Simon S   +11 more
core   +1 more source

Metabotropic Purinergic Receptors in Lipid Membrane Microdomains

Current Medicinal Chemistry, 2012
There is broad evidence that association of transmembrane receptors and signalling molecules with lipid rafts/caveolae provides an enriched environment for protein-protein interactions necessary for signal transduction, and a mechanism for the modulation of neurotransmitter and/or growth factor receptor function.
D' Ambrosi, N, Volonte, C
openaire   +4 more sources

Inferring Maps of Forces Inside Cell Membrane Microdomains [PDF]

Biophysical Journal, 2009
Mapping of the forces on biomolecules in cell membranes has spurred the development of effective labels, e.g. organic fluorophores and nanoparticles, to track trajectories of single biomolecules. Standard methods use particular statistics, namely the mean square displacement, to analyze the underlying dynamics.
Masson, J.-B., Casanova, Didier, Türkcan, Silvan, Voisinne, G., Popoff, Michel, Vergassola, M., Alexandrou, Antigoni   +6 more
openaire   +5 more sources

Membrane-Sculpting BAR Domains Generate Stable Lipid Microdomains

Cell Reports, 2013
Bin-Amphiphysin-Rvs (BAR) domain proteins are central regulators of many cellular processes involving membrane dynamics. BAR domains sculpt phosphoinositide-rich membranes to generate membrane protrusions or invaginations.
Hongxia Zhao, Alphée Michelot, Essi V. Koskela, Vadym Tkach, Dimitrios Stamou, David G. Drubin, Pekka Lappalainen   +6 more
doaj   +1 more source

Molecular, Enzymatic, and Cellular Characterization of Soluble Adenylyl Cyclase From Aquatic Animals. [PDF]

, 2018
The enzyme soluble adenylyl cyclase (sAC) is the most recently identified source of the messenger molecule cyclic adenosine monophosphate. sAC is evolutionarily conserved from cyanobacteria to human, is directly stimulated by [Formula: see text] ions ...
Acin-Perez, Barott, Barott, Barott, Beltrán, Berthelot, Bitterman, Bordeaux, Braun, Braun, Braun, Buck, Camacho Londoño, Chaloupka, Chen, Chen, Cooper, De Rasmo, Di Benedetto, Elliott, Farrell, Geng, Goldberg, Gordeladze, Hess, Hrdlickova, Jaiswal, Kobayashi, Leparc, Levin, Litvin, Magro, Neer, Neer, Nomura, Nomura, Ramos-Espiritu, Roa, Roa, Roa, Salem, Salomon, Schwencke, Steegborn, Steegborn, Stessin, Structural Genomics Consortium, Tresguerres, Tresguerres, Tresguerres, Tresguerres, Tresguerres, Wilson, Yeo, Zaccolo, Zippin, Zippin, Zippin, Zippin   +58 more
core   +2 more sources

Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity [PDF]

, 2009
L1-CAM (L1 cell-adhesion molecule), or more simply L1, plays an important role in the progression of human carcinoma. Overexpression promotes tumour-cell invasion and motility, growth in nude mice and tumour metastasis.
Riedle, Svenja, Kiefel, Helena, Gast, Daniela, Bondong, Sandra, Wolterink, Silke, Gutwein, Paul, Altevogt, Peter   +6 more
core   +2 more sources