Results 61 to 70 of about 34,175 (279)

Plasma membrane compartmentation in Saccharomyces cerevisiae

, 2009
In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core   +1 more source

Endothelial Cell Behavior Is Determined by Receptor Clustering Induced by Thrombospondin-1

Frontiers in Cell and Developmental Biology, 2021
The thrombospondins (TSPs) are a family of multimeric extracellular matrix proteins that dynamically regulate cellular behavior and response to stimuli.
Verônica Morandi, Jim Petrik, Jack Lawler   +2 more
doaj   +1 more source

Role of Membrane Microdomains in Compartmentation of cAMP Signaling [PDF]

PLoS ONE, 2014
Spatially restricting cAMP production to discrete subcellular locations permits selective regulation of specific functional responses. But exactly where and how cAMP signaling is confined is not fully understood. Different receptors and adenylyl cyclase isoforms responsible for cAMP production are not uniformly distributed between lipid raft and non ...
Agarwal, Shailesh R, Yang, Pei-Chi, Rice, Monica, Singer, Cherie A, Nikolaev, Viacheslav O, Lohse, Martin J, Clancy, Colleen E, Harvey, Robert D   +7 more
openaire   +7 more sources

Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine

Frontiers in Cell and Developmental Biology, 2020
Cytokinesis is the last step of cell division that partitions the cellular organelles and cytoplasm of one cell into two. In animal cells, cytokinesis requires Rho-GTPase-dependent assembly of F-actin and myosin II (actomyosin) to form an equatorial ...
Sabrya C. Carim, Amel Kechad, Gilles R. X. Hickson, Gilles R. X. Hickson   +3 more
doaj   +1 more source

Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe

mBio, 2021
Cholesterol influences membrane fluidity and forms membrane microdomains called lipid rafts that serve as organizing centers for the assembly of signaling molecules. Flotillin (FLOT) is a cholesterol-binding lipid-raft protein.
Weiyan Huang, Qingming Xiong, Mingqun Lin, Yasuko Rikihisa   +3 more
doaj   +1 more source

Transport and sorting of membrane lipids

, 1993
The lipid composition of cellular membranes may seem unnecessarily complex. However, the lipid composition of each membrane is carefully regulated by local metabolism and specificity in transport, marking the functional significance for the cell.
van Meer, G., Universiteit Utrecht, Dep Scheikunde, Membrane Enzymology   +3 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Nanoengineered Binetworks in Multifunctional Anionic Block Polymer Mesoblends for Improved Mechanical Properties

Advanced Functional Materials, EarlyView.
Mesoblends consist of a nanostructured polymer into which a second polymer is imbibed with a selective solvent. In this work, a solvent‐templatable pentablock terpolymer possessing a sulfonated midblock is modified with a hydrophilic polymer that is photocrosslinked in situ, yielding a hierarchical binetwork.
Kacie M. Wells, Ivan Kuzmenko, Reza A. Ghiladi, Richard J. Spontak   +3 more
wiley   +1 more source

Fatty Acyl Coenzyme A Synthetase Fat1p Regulates Vacuolar Structure and Stationary-Phase Lipophagy in Saccharomyces cerevisiae

Microbiology Spectrum, 2023
During yeast stationary phase, a single spherical vacuole (lysosome) is created by the fusion of several small ones. Moreover, the vacuolar membrane is reconstructed into two distinct microdomains.
Fan Qiu, Na Kang, Jinling Tan, Sisi Yan, Leiying Lin, Lipeng Cai, Joel M. Goodman, Qiang Gao   +7 more
doaj   +1 more source

Elucidating the Roles of Membrane Microdomains in Cellular Resilience [PDF]

, 2020
Plasma membrane compartments known as functional microdomains, such as membrane lipid rafts (MLRs) and caveolae, are critical in maintaining membrane structure and function which ultimately influences cellular survival.
Nazarbegian, Melody
core