Membrane Microdomains and Vascular Biology [PDF]
The classic model of cell plasma membrane organization is that of a uniform, fluid environment in which protein and lipid constituents diffuse rapidly in an unrestricted fashion. Recent experimental evidence, however, reveals a far more complex membrane organization consisting of microdomains assembled from lipid constituents that have distinct ...
R Preston, Mason, Robert F, Jacob
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The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif
Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains.
Peter G. Billcliff +3 more
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Steric exclusion and protein conformation determine the localization of plasma membrane transporters
The yeast plasma membrane consists of membrane microdomains with distinct protein composition. Here the authors use high-resolution single molecule imaging to observe diffusion of specific transmembrane proteins in and out of these microdomains, and ...
Frans Bianchi +9 more
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Lipid Rafts and Plant Gravisensitivity
The necessity to include plants as a component of a Bioregenerative Life Support System leads to investigations to optimize plant growth facilities as well as a better understanding of the plant cell membrane and its numerous activities in the signaling,
Elizabeth L. Kordyum +2 more
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Analysis of lipid-composition changes in plasma membrane microdomains[S]
Sphingolipids accumulate in plasma membrane microdomain sites, such as caveolae or lipid rafts. Such microdomains are considered to be important nexuses for signal transduction, although changes in the microdomain lipid components brought about by ...
Hideo Ogiso +2 more
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Variational Methods for Biomolecular Modeling
Structure, function and dynamics of many biomolecular systems can be characterized by the energetic variational principle and the corresponding systems of partial differential equations (PDEs).
A Ivankin +114 more
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Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir +7 more
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Tetraspanin-enriched microdomains: The building blocks of migrasomes
The migrasome is a newly discovered organelle of migrating cells. Migrasomes play diverse physiological roles including mitochondrial quality control, lateral transfer of material between cells, and delivery of signaling molecules to spatially defined ...
Yuwei Huang, Li Yu
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Membrane microdomains emergence through non-homogeneous diffusion [PDF]
In the classical view, cell membrane proteins undergo isotropic random motion, that is a 2D Brownian diffusion that should result in an homogeneous distribution of concentration. It is, however, far from the reality: Membrane proteins can assemble into so-called microdomains (sometimes called lipid rafts) which also display a specific lipid composition.
Soula, Hédi +2 more
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Endothelial Cell Behavior Is Determined by Receptor Clustering Induced by Thrombospondin-1
The thrombospondins (TSPs) are a family of multimeric extracellular matrix proteins that dynamically regulate cellular behavior and response to stimuli.
Verônica Morandi +2 more
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