Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton [PDF]
, 1999 CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells.
Ursula Günthert +17 more
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Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
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Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature. [PDF]
PLoS ONE, 2015 The formation of lipid microdomains ("rafts") is presumed to play an important role in various cellular functions, but their nature remains controversial.
Andrea Cremona +4 more
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Regulation of the leading edge motility by PI (4,5)P2-dependent lipid microdomains [PDF]
, 2005 The lipid second messenger PI(4,5)P2 modulates actin dynamics, and its local accumulation at plasmalemmal microdomains (rafts) might mediate regulation of protrusive motility.
Golub, Tamara
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Insulin Signaling in Microdomains of the Plasma Membrane [PDF]
Traffic, 2003 Although the effects of insulin on glucose and lipid metabolism are well documented, gaps remain in our understanding of the precise molecular mechanisms of signal transduction. Recent evidence suggests that compartmentalization of signaling molecules and metabolic enzymes may explain the unique cellular effects of the hormone.
Saltiel, Alan R., Pessin, Jeffrey E.
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Contributions of quantitative proteomics to understanding membrane microdomains
Journal of Lipid Research, 2009 Membrane microdomains, e.g., lipid rafts and caveolae, are crucial cell surface organelles responsible for many cellular signaling and communication events, which makes the characterization of their proteomes both interesting and valuable. They are large
Yu Zi Zheng, Leonard J. Foster
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T cell Ca2+ microdomains through the lens of computational modeling
Frontiers in Immunology, 2023 Cellular Ca2+ signaling is highly organized in time and space. Locally restricted and short-lived regions of Ca2+ increase, called Ca2+ microdomains, constitute building blocks that are differentially arranged to create cellular Ca2+ signatures ...
Diana C. Gil Montoya +4 more
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Plasma membrane microdomains in aging and disease [PDF]
Geriatrics & Gerontology International, 2010 The plasma membrane of eukaryotic cells participates in signal transduction and many other cellular events to maintain the physiological state of cells. In recent decades, much attention has been paid to membrane microdomains, called lipid rafts or membrane rafts, as signaling platforms in the plasma membrane.
Yoshiko, Ohno-Iwashita +3 more
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Microscopic simulation of membrane molecule diffusion on corralled membrane surfaces [PDF]
, 2008 The current understanding of how receptors diffuse and cluster in the plasma membrane is limited. Data from single-particle tracking and laser tweezer experiments have suggested that membrane molecule diffusion is affected by the presence of barriers ...
Edwards, Jeremy S. +4 more
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Use of dansyl-cholestanol as a probe of cholesterol behavior in membranes of living cells[S]
Journal of Lipid Research, 2010 While plasma membrane cholesterol-rich microdomains play a role in cholesterol trafficking, little is known about the appearance and dynamics of cholesterol through these domains in living cells.
Huan Huang +5 more
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