Results 41 to 50 of about 1,117,893 (276)
Use of dansyl-cholestanol as a probe of cholesterol behavior in membranes of living cells[S]
Journal of Lipid Research, 2010 While plasma membrane cholesterol-rich microdomains play a role in cholesterol trafficking, little is known about the appearance and dynamics of cholesterol through these domains in living cells.
Huan Huang +5 more
doaj +1 more source
Scientific Reports, 2021 Lipid rafts, sterol-rich and sphingolipid-rich microdomains on the plasma membrane are important in processes like cell signaling, adhesion, and protein and lipid transport.
Shiomi Koudatsu +8 more
doaj +1 more source
Insulin Signaling in Microdomains of the Plasma Membrane [PDF]
Traffic, 2003 Although the effects of insulin on glucose and lipid metabolism are well documented, gaps remain in our understanding of the precise molecular mechanisms of signal transduction. Recent evidence suggests that compartmentalization of signaling molecules and metabolic enzymes may explain the unique cellular effects of the hormone.
Saltiel, Alan R., Pessin, Jeffrey E.
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The role of type 4 phosphodiesterases in generating microdomains of cAMP: Large scale stochastic simulations [PDF]
, 2010 Cyclic AMP (cAMP) and its main effector Protein Kinase A (PKA) are critical for several aspects of neuronal function including synaptic plasticity. Specificity of synaptic plasticity requires that cAMP activates PKA in a highly localized manner despite ...
Terrin, A. +35 more
core +2 more sources
Caveolin is present in intestinal cells: role in cholesterol trafficking?
Journal of Lipid Research, 1998 It was postulated that specialized microdomains of the plasma membrane, consistent with caveolae, might play a role in cholesterol trafficking in intestinal cells.
F. Jeffrey Field +3 more
doaj +1 more source
Plasma membrane microdomains in aging and disease [PDF]
Geriatrics & Gerontology International, 2010 The plasma membrane of eukaryotic cells participates in signal transduction and many other cellular events to maintain the physiological state of cells. In recent decades, much attention has been paid to membrane microdomains, called lipid rafts or membrane rafts, as signaling platforms in the plasma membrane.
Yoshiko, Ohno-Iwashita +3 more
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The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
, 2007 Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Periasamy Selvaraj +2 more
core +1 more source
Membrane Microdomains and Vascular Biology [PDF]
Circulation, 2003 The classic model of cell plasma membrane organization is that of a uniform, fluid environment in which protein and lipid constituents diffuse rapidly in an unrestricted fashion. Recent experimental evidence, however, reveals a far more complex membrane organization consisting of microdomains assembled from lipid constituents that have distinct ...
R Preston, Mason, Robert F, Jacob
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Elucidating the Roles of Membrane Microdomains in Cellular Resilience [PDF]
, 2020 Plasma membrane compartments known as functional microdomains, such as membrane lipid rafts (MLRs) and caveolae, are critical in maintaining membrane structure and function which ultimately influences cellular survival.
Nazarbegian, Melody
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Steric exclusion and protein conformation determine the localization of plasma membrane transporters
Nature Communications, 2018 The yeast plasma membrane consists of membrane microdomains with distinct protein composition. Here the authors use high-resolution single molecule imaging to observe diffusion of specific transmembrane proteins in and out of these microdomains, and ...
Frans Bianchi +9 more
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