Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton [PDF]
, 1999 CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells.
Ursula Günthert +17 more
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Plasma membrane compartmentation in Saccharomyces cerevisiae [PDF]
, 2009 In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
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Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature. [PDF]
PLoS ONE, 2015 The formation of lipid microdomains ("rafts") is presumed to play an important role in various cellular functions, but their nature remains controversial.
Andrea Cremona +4 more
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Regulation of the leading edge motility by PI (4,5)P2-dependent lipid microdomains [PDF]
, 2005 The lipid second messenger PI(4,5)P2 modulates actin dynamics, and its local accumulation at plasmalemmal microdomains (rafts) might mediate regulation of protrusive motility.
Golub, Tamara
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Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
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Transport and sorting of membrane lipids [PDF]
, 1993 The lipid composition of cellular membranes may seem unnecessarily complex. However, the lipid composition of each membrane is carefully regulated by local metabolism and specificity in transport, marking the functional significance for the cell.
van Meer, G. +3 more
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Contributions of quantitative proteomics to understanding membrane microdomains
Journal of Lipid Research, 2009 Membrane microdomains, e.g., lipid rafts and caveolae, are crucial cell surface organelles responsible for many cellular signaling and communication events, which makes the characterization of their proteomes both interesting and valuable. They are large
Yu Zi Zheng, Leonard J. Foster
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T cell Ca2+ microdomains through the lens of computational modeling
Frontiers in Immunology, 2023 Cellular Ca2+ signaling is highly organized in time and space. Locally restricted and short-lived regions of Ca2+ increase, called Ca2+ microdomains, constitute building blocks that are differentially arranged to create cellular Ca2+ signatures ...
Diana C. Gil Montoya +4 more
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Microscopic simulation of membrane molecule diffusion on corralled membrane surfaces [PDF]
, 2008 The current understanding of how receptors diffuse and cluster in the plasma membrane is limited. Data from single-particle tracking and laser tweezer experiments have suggested that membrane molecule diffusion is affected by the presence of barriers ...
Edwards, Jeremy S. +4 more
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A proteomic analysis of lipid raft and GPI anchored proteins in Caenorhabditis elegans [PDF]
, 2010 Glycosylphosphatidylinositol (GPI) anchored proteins are a unique group of membrane proteins found on the surface and certain intracellular compartments of eukaryotic cells.
Rao, Wei
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