Results 71 to 80 of about 483,797 (293)

Membrane fusion in muscle development and repair [PDF]

open access: yesSeminars in Cell & Developmental Biology, 2015
Mature skeletal muscle forms from the fusion of skeletal muscle precursor cells, myoblasts. Myoblasts fuse to other myoblasts to generate multinucleate myotubes during myogenesis, and myoblasts also fuse to other myotubes during muscle growth and repair.
Alexis R, Demonbreun   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Annexins bend wound edges during plasma membrane repair [PDF]

open access: yes, 2020
The plasma membrane of eukaryotic cells defines the boundary to the extracellular envi-ronment and, thus provides essential protection from the surroundings.
Boye, Theresa Louise   +3 more
core   +1 more source

Importance of Membrane Curvature Near Hole Edges in Plasma Membrane Repair [PDF]

open access: yes, 2018
Maintaining integrity of the plasma membrane is essential for cell life. Thus, efficient cell membrane repair mechanisms are crucial for handling membrane disruptions resulting from external perturbations of eukaryotic cells.
Adam Cohen Simonsen   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Plasma Membrane Repair in Health and Disease [PDF]

open access: yes, 2016
Since an intact membrane is required for normal cellular homeostasis, membrane repair is essential for cell survival. Human genetic studies, combined with the development of novel animal models and refinement of techniques to study cellular injury, have now uncovered series of repair proteins highly relevant for human health.
Alexis R, Demonbreun   +1 more
openaire   +2 more sources

Bacterial membrane dynamics: Compartmentalization and repair

open access: yesMolecular Microbiology, 2023
AbstractIn every bacterial cell, the plasma membrane plays a key role in viability as it forms a selective barrier between the inside of the cell and its environment. This barrier function depends on the physical state of the lipid bilayer and the proteins embedded or associated with the bilayer.
Marc Bramkamp, Dirk‐Jan Scheffers
openaire   +2 more sources

Plasma membrane repair and cellular damage control: the annexin survival kit [PDF]

open access: yes, 2011
Plasmalemmal injury is a frequent event in the life of a cell. Physical disruption of the plasma membrane is common in cells that operate under conditions of mechanical stress.
Katia Monastyrskaya   +5 more
core   +1 more source

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