Results 71 to 80 of about 12,869 (202)

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Friction-Driven Scission by ESCRT-III Proteins [PDF]

, 2022
The cell membrane continuously undergoes fusion and fission in order to transport cargoes in and out of the cell. The endosomal sorting complexes required for transport (ESCRT) proteins are an ancient and ubiquitous membrane remodeling machinery present ...
Cada, Abraham King
core  

Critical bifurcations in deformable membrane necks under inhomogeneous curvature: constriction frustration vs. abscissional elongation

Frontiers in Soft Matter
Catenoid necks, as minimal surfaces with zero mean curvature (K=0), minimize bending energy and serve as geometric scaffolds for scissional membrane remodeling.
Adriana Aguilar-Maldonado, Francisco Monroy, Francisco Monroy, José A. Santiago, José A. Santiago, José A. Santiago   +5 more
doaj   +1 more source

Changes in ESCRT-III filament geometry drive membrane remodelling and fission in silico

BMC Biology, 2019
Background ESCRT-III is a membrane remodelling filament with the unique ability to cut membranes from the inside of the membrane neck. It is essential for the final stage of cell division, the formation of vesicles, the release of viruses, and membrane ...
Lena Harker-Kirschneck, Buzz Baum, And̄ela Šarić   +2 more
doaj   +1 more source

Atomic‐Level CuOx‐CoOx‐Pd Interfacial Engineering Enables Hierarchical Synergy for High‐Efficiency ORR Pathways and Boosted Power Output in Alkaline Fuel Cells

Advanced Science, EarlyView.
Atomically dispersed CuOx (CPCu‐1) forms isolated Cu–Ov sites that enable defect‐mediated O2 activation and fast electron/proton transfer via interfacial synergy. In contrast, thick CuOx clusters (CPCu‐10) promote a surface‐adsorption‐controlled pathway with intermediate accumulation, highlighting a mechanism switch from interfacial activation to ...
Yang‐Yang Hsu, Ching‐Hua Fan, Kuan‐Wen Wang, Kuang‐Kuo Wang, Nozomu Hiraoka, Hirofumi Ishii, Ting‐Shan Chan, Po‐Chun Chen, Tsan‐Yao Chen   +8 more
wiley   +1 more source

The kinetics of dynamin recruitment to sites of membrane scission. [PDF]

, 2012
(A) Sequential images from a TIR-FM image series of an NIH-3T3 fibroblast stably expressing dyn1(WT)-mCherry (Dyn1, lower panel) and transiently expressing TfR-pHl (TfR, upper panel). CCS were marked by spots of TfR-phl (spots, TfR images, pH7).
Marcus J. Taylor (173337), Marko Lampe (173339), Christien J. Merrifield (173341)   +2 more
core   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Curvature Sensing by a Viral Scission Protein [PDF]

, 2016
Membrane scission is the final step in all budding processes wherein a membrane neck is sufficiently constricted so as to allow for fission and the release of the budded particle.
Jeremy S. Rossman (2628127), Martyna, Agnieszka, Gomez-Llobregat, Jordi,, Agnieszka Martyna (2628115), Linden, Martin, Rossman, Jeremy S., Rossman, Jeremy S.,, Gomez-Llobregat, Jordi, Jordi Gómez-Llobregat (2831615), Lindén, Martin,, Martin Lindén (2831612), Martyna, Agnieszka,   +11 more
core   +1 more source

Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin-mediated endocytosis

Cell Reports, 2021
Summary: Clathrin-mediated endocytosis (CME) is critical for cellular signal transduction, receptor recycling, and membrane homeostasis in mammalian cells. Acute depletion of cholesterol disrupts CME, motivating analysis of CME dynamics in the context of
Ruthellen H. Anderson, Kem A. Sochacki, Harika Vuppula, Brandon L. Scott, Elizabeth M. Bailey, Maycie M. Schultz, Jason G. Kerkvliet, Justin W. Taraska, Adam D. Hoppe, Kevin R. Francis   +9 more
doaj   +1 more source

Non‐Noble Metal Nanocatalysts for Hydrogen Evolution

Advanced Science, EarlyView.
Recent overviews and latest developments of diverse classes of non‐noble catalysts for application toward high‐performance photocatalysis, thermocatalytic steam reforming, and electrocatalysis. Toward sustainability objectives, several advanced characterization tools in combination with the latest breakthroughs in machine learning for material ...
Lina Jaya Diguna, Gede Herry Arum Wijaya, Md Abdul Kuddus Sheikh, Tobias Haposan, Fidelis Stefanus Hubertson Simanjuntak, Arramel Arramel, Muhammad Danang Birowosuto, Konstantin Sergeevich Novoselov   +7 more
wiley   +1 more source