ESCRT-III mediated cell division in Sulfolobus acidocaldarius - a reconstitution perspective [PDF]
In the framework of synthetic biology, it has become an intriguing question what would be the minimal representation of cell division machinery. Thus, it seems appropriate to compare how cell division is realized in different microorganisms. Inparticular,
Härtel, T., Schwille, P.
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The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation
Membrane fusion and fission events at exoplasmic membrane surfaces are not well understood. Here the authors show that the C. elegans cell–cell fusogen AFF-1 is required for endocytic scission and apically-directed membrane trafficking during the ...
Fabien Soulavie +2 more
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The Toxoplasma gondii active serine hydrolase 4 regulates parasite division and intravacuolar parasite architecture [PDF]
Hydrolase are enzymes that regulate diverse biological processes, including posttranslational protein modifications. Recent work identified four active serine hydrolases (ASHs) in Toxoplasma gondii as candidate depalmitoylases. However, only TgPPT1 (ASH1)
Amara, Neri +7 more
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Stepwise remodeling and subcompartment formation in individual vesicles by three ESCRT-III proteins
Summary: The endosomal sorting complex required for transport (ESCRT) is a multi-protein machinery involved in several membrane remodeling processes. Different approaches have been used to resolve how ESCRT proteins scission membranes.
Yunuen Avalos-Padilla +6 more
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The role of traction in membrane curvature generation. [PDF]
Curvature of biological membranes can be generated by a variety of molecular mechanisms including protein scaffolding, compositional heterogeneity, and cytoskeletal forces.
Alimohamadi, H +4 more
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ESCRT-III-dependent and -independent egress of herpesviruses
Enveloped viruses complete their replication cycle by forming virions that bud from infected cells through membrane scission. The mechanisms by which this is achieved are less well-understood than the well-characterized membrane scission of vesicles ...
Jun Arii
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A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling
Membrane protein recycling systems are essential for maintenance of the endosome-lysosome system. In yeast, retromer and Snx4 coat complexes are recruited to the endosomal surface, where they recognize cargos. They sort cargo and deform the membrane into
Sho W Suzuki +5 more
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ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release. [PDF]
The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol.
Koehler, Carla M, Steffen, Janos
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A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells. [PDF]
Dynamin Guanosine Triphosphate hydrolases (GTPases) are best studied for their role in the terminal membrane fission process of clathrin-mediated endocytosis (CME), but they have also been proposed to regulate earlier stages of CME.
Saipraveen Srinivasan +7 more
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Thermal decomposition of a honeycomb-network sheet - A Molecular Dynamics simulation study
The thermal degradation of a graphene-like two-dimensional triangular membrane with bonds undergoing temperature-induced scission is studied by means of Molecular Dynamics simulation using Langevin thermostat.
A. Milchev +4 more
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