SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis. [PDF]
, 2010 Hereditary spastic paraplegias (HSPs, SPG1-46) are inherited neurological disorders characterized by lower extremity spastic weakness. Loss-of-function SPG20 gene mutations cause an autosomal recessive HSP known as Troyer syndrome.
Bakowska, Joanna C +5 more
core +3 more sources
ESCRT machinery mediates selective microautophagy of endoplasmic reticulum in yeast
, 2019 ER-phagy, the selective autophagy of endoplasmic reticulum (ER), safeguards organelle homeostasis by eliminating misfolded proteins and regulating ER size. ER-phagy can occur by macroautophagic and microautophagic mechanisms.
Charlotta Funaya +12 more
core +2 more sources
Perturbing dynamin reveals potent effects on the Drosophila circadian clock. [PDF]
PLoS ONE, 2009 BACKGROUND:Transcriptional feedback loops are central to circadian clock function. However, the role of neural activity and membrane events in molecular rhythms in the fruit fly Drosophila is unclear.
Valerie L Kilman +4 more
doaj +1 more source
Influenza virus morphogenesis and budding. [PDF]
, 2009 Influenza viruses are enveloped, negative stranded, segmented RNA viruses belonging to Orthomyxoviridae family. Each virion consists of three major sub-viral components, namely (i) a viral envelope decorated with three transmembrane proteins ...
Balogun, Rilwan A +4 more
core +1 more source
Inhomogeneous Canham–Helfrich Abscission in Catenoid Necks under Critical Membrane Mosaicity
Membranes, 2023 The mechanical effects of membrane compositional inhomogeneities are analyzed in a process analogous to neck formation in cellular membranes. We cast on the Canham–Helfrich model of fluid membranes with both the spontaneous curvature and the surface ...
José Antonio Santiago, Francisco Monroy
doaj +1 more source
Ageing of polysulfone membranes in contact with bleach solution: Role of radical oxidation and of some dissolved metal ions [PDF]
, 2008 In water production plants using membrane processes, contact with chemicals such as chlorine plays an important role in membrane ageing. This experimental study was aimed at gaining a better understanding of the effect of hypochlorite cleaning solutions ...
Aimar, Pierre +3 more
core +1 more source
Eukaryotic-Like Virus Budding in
mBio, 2016 Similar to many eukaryotic viruses (and unlike bacteriophages), viruses infecting archaea are often encased in lipid-containing envelopes. However, the mechanisms of their morphogenesis and egress remain unexplored.
Emmanuelle R. J. Quemin +5 more
doaj +1 more source
Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding
, 2017 During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F. +2 more
core +1 more source
Advanced Functional Materials, EarlyView.Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco +7 more
wiley +1 more source
Control of lipid organization and actin assembly during clathrin-mediated endocytosis by the cytoplasmic tail of the rhomboid protein Rbd2. [PDF]
, 2015 Clathrin-mediated endocytosis (CME) is facilitated by a precisely regulated burst of actin assembly. PtdIns(4,5)P2 is an important signaling lipid with conserved roles in CME and actin assembly regulation. Rhomboid family multipass transmembrane proteins
Cortesio, Christa L +2 more
core +1 more source