Results 31 to 40 of about 26,768 (226)
The final twist in endocytic membrane scission [PDF]
Nature Cell Biology, 2021 Many endocytic uptake events depend on the 'pinchase' activity of dynamin. By measuring the orientation of single gold nanorods, a new study reveals that invaginated clathrin-coated endocytic pits undergo a strong rotational twist prior to or concomitant with their detachment.
Johannes, Ludger, Valades-Cruz, Cesar
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Dynamin: Membrane Scission Meets Physics [PDF]
Current Biology, 2012 Dynamin hydrolyzes GTP to constrict and sever membranes. Experimental advances bring dynamin into the realm of physics and reveal key roles for membrane tension and bending at the edge of the constriction.
Hurley, James H., Hinshaw, Jenny E.
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ESCRT membrane scission revealed by optical tweezers. [PDF]
The FASEB Journal, 2018 ESCRT proteins catalyze the function of membrane budding and scission from the inside of the cytosol to the outside. This process is fundamental in cell biology, comprising multivesicular endosome biogenesis, cytokinesis, viral budding (e.g. HIV, Ebola, Dengue) and other pathways.
Johannes Schöneberg +10 more
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Programmable DNA shell scaffolds for directional membrane budding [PDF]
Nature CommunicationsIn the pursuit of replicating biological processes at the nanoscale, controlling cellular membrane dynamics has emerged as a key area of interest. Here, we report a system mimicking virus assembly to control directional membrane budding.
Michael T. Pinner, Hendrik Dietz
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Determinants of endocytic membrane geometry, stability, and scission [PDF]
Proceedings of the National Academy of Sciences, 2011 During endocytic vesicle formation, distinct subdomains along the membrane invagination are specified by different proteins, which bend the membrane and drive scission. Bin-Amphiphysin-Rvs (BAR) and Fer-CIP4 homology-BAR (F-BAR) proteins can induce membrane curvature and have been suggested to facilitate membrane invagination and scission.
Takuma, Kishimoto +5 more
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Shear-Driven Instabilities of Membrane Tubes and Dynamin-Induced Scission [PDF]
Physical Review Letters, 2020 Main Text: 5 pages, 3 figures + S.I. 14 pages, 6 figures (Accepted Version)
Sami C. Al-Izzi +2 more
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Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna +29 more
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Crucial Role for Membrane Fluidity in Proliferation of Primitive Cells
Cell Reports, 2012 The cell wall is a defining structural feature of the bacterial subkingdom. However, most bacteria are capable of mutating into a cell-wall-deficient “L-form” state, requiring remarkable physiological and structural adaptations. L-forms proliferate by an
Romain Mercier +2 more
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Regulation of membrane scission in yeast endocytosis
, 2021 AbstractDuring clathrin-mediated endocytosis, a flat plasma membrane is shaped into an invagination that undergoes scission to form a vesicle. In mammalian cells, the force that drives the transition from invagination to vesicle is primarily provided by the GTPase dynamin that acts in concert with crescent-shaped BAR domain proteins.
Deepikaa Menon, Marko Kaksonen
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CryoEM structure of the super-constricted two-start dynamin 1 filament
Nature Communications, 2021 Dynamin mediates the fission of vesicles during endocytosis. Here, the authors report the cryoEM structure of a super-constricted two-start dynamin 1 filament- one of the two known helical forms of dynamin, with insights into the molecular mechanisms of ...
Jiwei Liu +4 more
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