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Membrane Transport Proteins in Osteoclasts: The Ins and Outs. [PDF]
During bone resorption, the osteoclast must sustain an extraordinarily low pH environment, withstand immense ionic pressures, and coordinate nutrient and waste exchange across its membrane to sustain its unique structural and functional polarity.
Ribet ABP, Ng PY, Pavlos NJ.
europepmc +7 more sources
Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor. [PDF]
Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Van Campenhout R+4 more
europepmc +3 more sources
Single-Molecule FRET of Membrane Transport Proteins. [PDF]
AbstractUncovering the structure and function of biomolecules is a fundamental goal in structural biology. Membrane‐embedded transport proteins are ubiquitous in all kingdoms of life. Despite structural flexibility, their mechanisms are typically studied by ensemble biochemical methods or by static high‐resolution structures, which complicate a ...
Bartels K+3 more
europepmc +7 more sources
Genes for Membrane Transport Proteins: Not So Rare in Viruses. [PDF]
Some viruses have genes encoding proteins with membrane transport functions. It is unknown if these types of proteins are rare or are common in viruses.
Greiner T+3 more
europepmc +3 more sources
Transport of Ciliary Membrane Proteins [PDF]
Cilia and flagella are highly conserved organelles in eukaryotic cells that drive cell movement and act as cell antennae that receive and transmit signals.
Huan Long, Kaiyao Huang
doaj +3 more sources
A Continuum Poisson-Boltzmann Model for Membrane Channel Proteins [PDF]
Membrane proteins constitute a large portion of the human proteome and perform a variety of important functions as membrane receptors, transport proteins, enzymes, signaling proteins, and more. The computational studies of membrane proteins are usually much more complicated than those of globular proteins.
Diao, Jianxiong+4 more
arxiv +6 more sources
Collective Molecular Dynamics in Proteins and Membranes [PDF]
The understanding of dynamics and functioning of biological membranes and in particular of membrane embedded proteins is one of the most fundamental problems and challenges in modern biology and biophysics. In particular the impact of membrane composition and properties and of structure and dynamics of the surrounding hydration water on protein ...
Caillé A.+3 more
arxiv +4 more sources
Anomalous diffusion of proteins in sheared lipid membranes [PDF]
We use coarse grained molecular dynamics simulations to investigate diffusion properties of sheared lipid membranes with embedded transmembrane proteins. In membranes without proteins, we find normal in-plane diffusion of lipids in all flow conditions. Protein embedded membranes behave quite differently: by imposing a simple shear flow and sliding the ...
Jalali, Mir Abbas, Khoshnood, Atefeh
arxiv +3 more sources
Transport of proteins across mitochondrial membranes [PDF]
The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes of the mitochondrion without interfering with the integrity or functions of the organelle.
Neupert, Walter
openaire +6 more sources
Updating view of membrane transport proteins by simulation studies. [PDF]
Sumikama T+4 more
europepmc +2 more sources