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Membrane Transport Proteins in Osteoclasts: The Ins and Outs. [PDF]

open access: yesFront Cell Dev Biol, 2021
During bone resorption, the osteoclast must sustain an extraordinarily low pH environment, withstand immense ionic pressures, and coordinate nutrient and waste exchange across its membrane to sustain its unique structural and functional polarity.
Ribet ABP, Ng PY, Pavlos NJ.
europepmc   +7 more sources

Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor. [PDF]

open access: yesBiomolecules, 2021
Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Van Campenhout R   +4 more
europepmc   +3 more sources

Single-Molecule FRET of Membrane Transport Proteins. [PDF]

open access: yesChembiochem, 2021
AbstractUncovering the structure and function of biomolecules is a fundamental goal in structural biology. Membrane‐embedded transport proteins are ubiquitous in all kingdoms of life. Despite structural flexibility, their mechanisms are typically studied by ensemble biochemical methods or by static high‐resolution structures, which complicate a ...
Bartels K   +3 more
europepmc   +7 more sources

Genes for Membrane Transport Proteins: Not So Rare in Viruses. [PDF]

open access: yesViruses, 2018
Some viruses have genes encoding proteins with membrane transport functions. It is unknown if these types of proteins are rare or are common in viruses.
Greiner T   +3 more
europepmc   +3 more sources

Transport of Ciliary Membrane Proteins [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
Cilia and flagella are highly conserved organelles in eukaryotic cells that drive cell movement and act as cell antennae that receive and transmit signals.
Huan Long, Kaiyao Huang
doaj   +3 more sources

A Continuum Poisson-Boltzmann Model for Membrane Channel Proteins [PDF]

open access: yesarXiv, 2017
Membrane proteins constitute a large portion of the human proteome and perform a variety of important functions as membrane receptors, transport proteins, enzymes, signaling proteins, and more. The computational studies of membrane proteins are usually much more complicated than those of globular proteins.
Diao, Jianxiong   +4 more
arxiv   +6 more sources

Collective Molecular Dynamics in Proteins and Membranes [PDF]

open access: yesBiointerphases Volume 3, Issue 2, pp. FB83-FB90 (June 2008), 2008
The understanding of dynamics and functioning of biological membranes and in particular of membrane embedded proteins is one of the most fundamental problems and challenges in modern biology and biophysics. In particular the impact of membrane composition and properties and of structure and dynamics of the surrounding hydration water on protein ...
Caillé A.   +3 more
arxiv   +4 more sources

Anomalous diffusion of proteins in sheared lipid membranes [PDF]

open access: yes, 2013
We use coarse grained molecular dynamics simulations to investigate diffusion properties of sheared lipid membranes with embedded transmembrane proteins. In membranes without proteins, we find normal in-plane diffusion of lipids in all flow conditions. Protein embedded membranes behave quite differently: by imposing a simple shear flow and sliding the ...
Jalali, Mir Abbas, Khoshnood, Atefeh
arxiv   +3 more sources

Transport of proteins across mitochondrial membranes [PDF]

open access: yesThe Clinical Investigator, 1994
The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes of the mitochondrion without interfering with the integrity or functions of the organelle.
Neupert, Walter
openaire   +6 more sources

Updating view of membrane transport proteins by simulation studies. [PDF]

open access: yesBiophys Physicobiol, 2023
Sumikama T   +4 more
europepmc   +2 more sources

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