Results 11 to 20 of about 1,050,062 (243)

Mechanism Study of Proteins under Membrane Environment

Membranes, 2022
Membrane proteins play crucial roles in various physiological processes, including molecule transport across membranes, cell communication, and signal transduction. Approximately 60% of known drug targets are membrane proteins.
Yue Zhang, Xiaohong Zhu, Honghui Zhang, Junfang Yan, Peiyi Xu, Peng Wu, Song Wu, Chen Bai   +7 more
doaj   +1 more source

Regulation of Plasma Membrane Sterol Homeostasis by Nonvesicular Lipid Transport

Contact, 2021
Sterol contributes to the structural integrity of cellular membranes and plays an important role in the regulation of cell signaling in eukaryotes. It is either produced in the endoplasmic reticulum or taken up from the extracellular environment. In most
Dylan Hong Zheng Koh, Yasunori Saheki
doaj   +1 more source

Outer Membrane Vesicles of Acinetobacter baumannii DS002 Are Selectively Enriched with TonB-Dependent Transporters and Play a Key Role in Iron Acquisition

Microbiology Spectrum, 2022
Outer membrane vesicles (OMVs) of Acinetobacter baumannii DS002 carry proteins which perform selective biological functions. The proteins involved in cell wall/membrane biogenesis and inorganic ion transport and metabolism occupied a significant portion ...
Ganeshwari Dhurve, Ashok Kumar Madikonda, Medicharla Venkata Jagannadham, Dayananda Siddavattam   +3 more
doaj   +1 more source

Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy

Molecular Biomedicine, 2022
Intracellular vesicle trafficking is the fundamental process to maintain the homeostasis of membrane-enclosed organelles in eukaryotic cells. These organelles transport cargo from the donor membrane to the target membrane through the cargo containing ...
Lele Cui, Hao Li, Yufeng Xi, Qianli Hu, Huimin Liu, Jiaqi Fan, Yijuan Xiang, Xing Zhang, Weiwei Shui, Ying Lai   +9 more
doaj   +1 more source

Extragenic Suppression analysis of TS mutations using Sec61p [PDF]

, 2007
During synthesis, secretory and membrane proteins are cotranslationally translocated into the lumen of the endoplasmic reticulum through an aqueous gated channel.
Sterling Smith
core   +2 more sources

New putative chloroplast vesicle transport components and cargo proteins revealed using a bioinformatics approach: an Arabidopsis model. [PDF]

PLoS ONE, 2013
Proteins and lipids are known to be transported to targeted cytosolic compartments in vesicles. A similar system in chloroplasts is suggested to transfer lipids from the inner envelope to the thylakoids. However, little is known about both possible cargo
Nadir Zaman Khan, Emelie Lindquist, Henrik Aronsson   +2 more
doaj   +1 more source

Occurrence and potential mechanism of holin-mediated non-lytic protein translocation in bacteria

Microbial Cell, 2022
Holins are generally believed to generate large membrane lesions that permit the passage of endolysins across the cytoplasmic membrane of prokaryotes, ultimately resulting in cell wall degradation and cell lysis. However, there are more and more examples
Thomas Brüser, Denise Mehner-Breitfeld
doaj   +1 more source

Teleological cooption of Mycobacterium tuberculosis PE/PPE proteins as porins: Role in molecular immigration and emigration

International Journal of Medical Microbiology, 2021
Permeation through bacterial cells for exchange or uptake of biomolecules and ions invariably depend upon the existence of pore-forming proteins (porins) in their outer membrane. Mycobacterium tuberculosis (M.
Aquib Ehtram, Mohd Shariq, Sabeeha Ali, Neha Quadir, Javaid A. Sheikh, Faraz Ahmad, Tarina Sharma, Nasreen Z. Ehtesham, Seyed E. Hasnain   +8 more
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Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in a Cell Free System from Neurospora crassa [PDF]

, 1977
Synthesis and transport of mitochondrial proteins were followed in a cell-free homogenate of Neurospora crassa in which mitochondrial translation was inhibited. Proteins synthesized on cytoplasmic ribosomes are transferred into the mitochondrial fraction.
Andrews T. M., Bingham R. W., Blair G. E., Davidian N. M., Dobberstein B., Dolken G., Gaitskhoki V. S., Godinot C., Gonzalez-Cadavid N. F., Gonzalez-Cadavid N. F., Grollmann A. P., Hallermayer G., Kadenbach B., Kadenbach B., Kadenbach B., Kellems R. E., Kellems R. E., Kellems R. E., Kellems R. E., Marra E., Milstein C., Morris A., O'Brien R. L., Pfaff E., Redman C. M., Shore G. C., Takanami M., Tata J. R., Weiss H., Wojtczak L., Wojtczak L.   +30 more
core   +1 more source

Active Nuclear Import of Membrane Proteins Revisited

Cells, 2015
It is poorly understood how membrane proteins destined for the inner nuclear membrane pass the crowded environment of the Nuclear Pore Complex (NPC). For the Saccharomyces cerevisiae proteins Src1/Heh1 and Heh2, a transport mechanism was proposed where ...
Justyna K. Laba, Anton Steen, Petra Popken, Alina Chernova, Bert Poolman, Liesbeth M. Veenhoff   +5 more
doaj   +1 more source