Results 271 to 280 of about 2,949,634 (335)

High-Yield Outer Membrane Vesicles Derived From Probiotics as a Nanoplatform for Precise Treatment and Prophylaxis of Pseudomonas aeruginosa Infection. [PDF]

J Extracell Vesicles
Yang Y, Xu L, Li Y, Sun Y, Tang Y, Xiao Z, Li M, Chen Y, Wang Y, Shen X.   +9 more
europepmc   +1 more source

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source

A distinct subpopulation of membrane vesicles in <i>Pseudomonas putida</i> is enriched in enzymes for lignin catabolism. [PDF]

Appl Environ Microbiol
Werner AZ, Giannone RJ, Keller MJ, Plavchak C, Carper DL, Abraham PE, Wilkes RA, Aristilde L, Salvachúa D, Ratanathanawongs Williams SK, Hettich RL, Beckham GT.   +11 more
europepmc   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Harnessing Lactiplantibacillus plantarum EP21 and its membrane vesicles to inhibit myopia development. [PDF]

Gut Microbes
Lin CF, Hsu YA, Chou YL, Chen YC, Lin ES, Tien PT, Chen JJ, Wu MY, Lin CH, Lin HJ, Wan L.   +10 more
europepmc   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Investigating the activation of the immune response by outer membrane vesicles from Bacteroides fragilis using a human gastrointestinal cell system. [PDF]

J Immunol
Jefferis TM, Scano C, Ashraf A, Stevens DM, Sevcik A, Bruce E, Greathouse L, Sayes CM.   +7 more
europepmc   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Acinetobacter baumannii as a Model for the Study and Application of Gram-Negative Outer Membrane Vesicles: A Systematic Review. [PDF]

Microb Biotechnol
Cano-Castaño B, López-Siles M, Nonnoi F, Pérez A, Corral Lugo A, McConnell MJ.   +5 more
europepmc   +1 more source