Results 231 to 240 of about 429,538 (268)
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Seminars in Immunology, 2004
CD4 T-cell memory is in some ways more enigmatic than CD8 T-cell memory. This is mostly due to the fact that CD4 T cells tend to expand far less in response to antigenic stimuli, thereby thwarting attempts at their detection during the course of an immune response.
Brigitta, Stockinger +2 more
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CD4 T-cell memory is in some ways more enigmatic than CD8 T-cell memory. This is mostly due to the fact that CD4 T cells tend to expand far less in response to antigenic stimuli, thereby thwarting attempts at their detection during the course of an immune response.
Brigitta, Stockinger +2 more
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Science, 1996
Viruses cause immediate induction of type I interferons (which include IFN-alpha and IFN-beta). These IFN I cytokines limit spread of the virus until antigen-specific responses can fully control the infection. A report by Tough et al . ( p.
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Viruses cause immediate induction of type I interferons (which include IFN-alpha and IFN-beta). These IFN I cytokines limit spread of the virus until antigen-specific responses can fully control the infection. A report by Tough et al . ( p.
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1990
The immune response of the host to its environment necessitates a finely tuned network of feedback mechanisms designed to provide for an effective humoral and cellular response to potential pathogens without damage to self tissues. Therefore the maintenance of the immunological milieu interieur depends not only on counterbalances to regulate the extent
S, Adelstein +3 more
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The immune response of the host to its environment necessitates a finely tuned network of feedback mechanisms designed to provide for an effective humoral and cellular response to potential pathogens without damage to self tissues. Therefore the maintenance of the immunological milieu interieur depends not only on counterbalances to regulate the extent
S, Adelstein +3 more
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Science, 2001
In typical immune responses, contact with antigen causes naı̈ve T cells to proliferate and differentiate into effector cells. After the pathogen is destroyed, most effector T cells are eliminated—thereby preserving the primary T cell repertoire—but some cells survive and form long-lived memory cells. During each stage of this process, the life or death
J, Sprent, D F, Tough
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In typical immune responses, contact with antigen causes naı̈ve T cells to proliferate and differentiate into effector cells. After the pathogen is destroyed, most effector T cells are eliminated—thereby preserving the primary T cell repertoire—but some cells survive and form long-lived memory cells. During each stage of this process, the life or death
J, Sprent, D F, Tough
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Modelling T-cell memory by genetic marking of memory T cells in vivo
Nature, 1999Immunological memory is the ability of the immune system to respond with enhanced vigour to pathogens that have been encountered in the past. Following infection or immunization, most effector T cells undergo apoptotic cell death, but a small fraction of these cells, proportional to the early antigen load and initial clonal burst size, persist in the ...
Jacob, Joshy, Baltimore, David
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Immunological memory in T cells
Current Opinion in Immunology, 1991CD4 and CD8 T lymphocytes can be further subdivided using antibodies to isoforms of CD45 with restricted cellular distributions. These further subsets, detected in man, rodents and sheep, differ in surface phenotypes, rate of cycling, migration and response to recall antigens. Their lineage relationship has still not been fully established.
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CD30—Governor of Memory T Cells?
Annals of the New York Academy of Sciences, 2002Abstract: CD30 is well recognized as a marker expressed by a heterogeneous group of lymphomas and in several immune and autoimmune disorders. However, the function of CD30 in theses diseases or in the normal immune response has remained unclear. Studying gene expression patterns induced by stimulating CD30 signals on a large granular lymphoma cell ...
Podack, Eckhard R. +3 more
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1990
Generally, it is accepted that immunological memory exists at both the B- and the T-cell level (reviewed in Katz 1977). It has been known for more than 100 years that the persistence of high antibody titers (Fig. 1) can be lifelong after viral infections and that delayed-type hypersensitivity can be demonstrated for a long time by challenging with a ...
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Generally, it is accepted that immunological memory exists at both the B- and the T-cell level (reviewed in Katz 1977). It has been known for more than 100 years that the persistence of high antibody titers (Fig. 1) can be lifelong after viral infections and that delayed-type hypersensitivity can be demonstrated for a long time by challenging with a ...
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Fuzzy Sets and Systems, 1999
Abstract The paper deals with design problems of trigger (T)-type fuzzy memory cell. The authors suggest six types of T cell, which can be used in temporal fuzzy logic: memory item of 1 fuzzy bit information, converter from fuzzy date to fuzzy time interval, cell of fuzzy register, item of fuzzy memory, fuzzy delay circuit and so on.
Jernej Virant, Nikolaj Zimic, Miha Mraz
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Abstract The paper deals with design problems of trigger (T)-type fuzzy memory cell. The authors suggest six types of T cell, which can be used in temporal fuzzy logic: memory item of 1 fuzzy bit information, converter from fuzzy date to fuzzy time interval, cell of fuzzy register, item of fuzzy memory, fuzzy delay circuit and so on.
Jernej Virant, Nikolaj Zimic, Miha Mraz
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Nature, 2000
Memory is a long-recognized, crucial and poorly understood property of adaptive immunity. Jacob and Baltimore have designed an elegant genetic approach to marking memory T cells and their precursors irreversibly and have obtained intriguing results.
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Memory is a long-recognized, crucial and poorly understood property of adaptive immunity. Jacob and Baltimore have designed an elegant genetic approach to marking memory T cells and their precursors irreversibly and have obtained intriguing results.
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