Results 231 to 240 of about 1,044,819 (294)

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

Bystander CD8⁺ conventional memory versus virtual memory T cells in the initial days post-<i>Trypanosoma cruzi</i> infection. [PDF]

Front Immunol
Viano ME, Baigorri RE, Bergero G, Aoki MP, Lidon NL, Teixeira MG, Herrera MR, Motran CC, Cerban FM, Stempin CC, Rodriguez-Galan MC.   +10 more
europepmc   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

IL-1β-induced STAT3 activation drives IL-17-producing CD8⁺ tissue-resident memory T cells and exacerbates chronic psoriasis. [PDF]

J Transl Med
Kim T, Lee CR, Lee SY, Lee AR, Lee YJ, Bang CH, Bang CH, Cho ML.   +7 more
europepmc   +1 more source

Temporally Delayed Deployment of Photo‐Responsive Liquid Crystal Polymer Networks Toward Neural Interfaces

Advanced Healthcare Materials, EarlyView.
Deployable medical devices typically need external stimuli to trigger deployment. However, external stimuli are difficult to supply within tissues. Here, we describe a strategy to deploy small‐scale structures into soft tissues after insertion without the need for any stimulus. We demonstrate deployment within a tissue phantom.
Yeh‐Chia Tseng, Eleanor Nguyen Jeakle, Mahjabeen Javed, Rajasree Gopala Krishnan, Thomas J. Smith, Yoo Jin Lee, Sahana Dhananjayan, Sasha M. George, Manivannan Sivaperuman Kalairaj, Ali Hasan Zuaiter, Majed O. Althumayri, Hatice Ceylan Koydemir, Joseph J. Pancrazio, Taylor H. Ware   +13 more
wiley   +1 more source

IL-32-producing CD8+ memory T cells define immunoregulatory niches in human cutaneous leishmaniasis. [PDF]

J Clin Invest
Dey NS, Dey S, Brown N, Senarathne S, Campos Reis L, Sengupta R, Lindoso JA, James SR, Gilbert L, Boucher D, Chatterjee M, Goto H, Ranasinghe S, Kaye PM.   +13 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Alarm Functions of PD-1+ Brain-Resident Memory T Cells. [PDF]

J Immunol
Musial SC, Kleist SA, Degefu HN, Ford MA, Chen T, Isaacs JF, Boussiotis VA, Skorput AGJ, Rosato PC.   +8 more
europepmc   +1 more source

Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing

Advanced Materials, EarlyView.
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long, Huanyu Zhou, Jaewan Ko, Hongwei Tan, Jaemin Lim, Yanfei Zhao, Daehan Kang, Eojin Yoon, Gyeong‐Tak Go, Somin Kim, Seung‐Woo Lee, Chan‐Yul Park, Hyojun Choi, Hyeran Kim, Hyung Joong Yun, Sung Hyuk Park, Kwan Sik Park, Jeong Woo Park, Mungeun Kim, Yong Soo Cho, Ho Won Jang, Wenqiang Yang, Min Hyuk Park, Wan Ki Bae, Sebastiaan van Dijken, Joona Bang, Tae‐Woo Lee   +26 more
wiley   +1 more source

Allergen-specific circulating CLA⁺ memory T cells stratify IL-22 response in atopic dermatitis skin. [PDF]

Front Immunol
García-Jiménez I, Sans-de San Nicolàs L, Díez-Ribas S, Curto-Barredo L, Bertolín-Colilla M, Vivancos-Melenchón A, Figueras-Nart I, Bonfill-Ortí M, Ryzhkova A, Ferran M, Czarnowicki T, Pujol RM, Santamaria-Babí LF.   +12 more
europepmc   +1 more source