Results 1 to 10 of about 1,141,533 (358)

Dietary factors and risk for asthma: A Mendelian randomization analysis

Frontiers in Immunology, 2023
Background Previous research has found a link between dietary factors and asthma. However, few studies have analyzed the relationship between dietary factors and asthma using Mendelian randomization.
Wenwen Yang, Yanjiang Yang, Li He, M. Zhang, Shuo Sun, Feng Wang, Biao Han   +6 more
semanticscholar   +4 more sources

Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis

Brain : a journal of neurology, 2023
Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple sclerosis have been developed and widely used. However, existing medications for multiple sclerosis were far from satisfactory due to their failure to suppress ...
Jianfeng Lin, Jiawei Zhou, Yan Xu
semanticscholar   +1 more source

COVID-19 is associated with the risk of cardiovascular disease death: A two-sample Mendelian randomization study

Frontiers in Cardiovascular Medicine, 2022
ObjectiveThis study aimed to estimate the causal effects of Coronavirus disease 2019 susceptibility and hospitalization on cardiovascular disease death using two-sample Mendelian randomization analysis.MethodsWe used statistics from a genome-wide ...
Jia-peng Miao, Xiao-yu Gu, Rui-zheng Shi
doaj   +1 more source

Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis

eLife, 2023
Background: Whether the positive associations of smoking and alcohol consumption with gastrointestinal diseases are causal is uncertain. We conducted this Mendelian randomization (MR) to comprehensively examine associations of smoking and alcohol ...
S. Yuan, Jie Chen, Xixian Ruan, Yuhao Sun, Ke Zhang, Xiao-Yang Wang, Xue Li, D. Gill, S. Burgess, E. Giovannucci, S. Larsson   +10 more
semanticscholar   +1 more source

The causality between intestinal flora and allergic diseases: Insights from a bi-directional two-sample Mendelian randomization analysis

Frontiers in Immunology, 2023
Background Growing evidence shows a significant association between intestinal flora and allergic diseases, specifically atopic dermatitis (AD), allergic rhinitis (AR), and allergic asthma (AA).
Qiu-Yu Jin, Feihong Ren, Dan Dai, Nan Sun, Yiyun Qian, Ping Song   +5 more
semanticscholar   +1 more source

RETRACTED: A Mendelian Randomization Analysis Investigates Causal Associations between Inflammatory Bowel Diseases and Variable Risk Factors

Nutrients, 2023
The question of whether variable risk factors and various nutrients are causally related to inflammatory bowel diseases (IBDs) has remained unanswered so far.
M. Saadh, R. Pal, J. L. Arias-Gonzáles, Juan Carlos Orosco Gavilán, Darshan Jc, Mohamed Mohany, Salim S. Al-Rejaie, A. Bahrami, Mustafa jawad Kadham, A. Amin, Hrosti Georgia   +10 more
semanticscholar   +1 more source

Causal relationships between the gut microbiome, blood lipids, and heart failure: a Mendelian randomization analysis.

European Journal of Preventive Cardiology, 2023
BACKGROUND Studies have linked gut microbiome and heart failure (HF). However, their causal relationships and potential mediating factors have not been well defined. AIMS To investigate the causal relationships between the gut microbiome and HF and the
H. Dai, T. Hou, Qi Wang, Y. Hou, Tiange Wang, Jie Zheng, Hong Lin, Zhiyun Zhao, Mian Li, Shuangyuan Wang, Di Zhang, M. Dai, R. Zheng, Jieli Lu, Yu Xu, Yuhong Chen, G. Ning, Weiqing Wang, Y. Bi, Min Xu   +19 more
semanticscholar   +1 more source

Causal relationship between obesity and iron deficiency anemia: a two-sample Mendelian randomization study

Frontiers in Public Health, 2023
BackgroundObservational studies have suggested an association between obesity and iron deficiency anemia, but such studies are susceptible to reverse causation and residual confounding.
Tingting Wang, Qi Gao, Yuanyuan Yao, Ge Luo, Tao Lv, Guangxin Xu, Mingxia Liu, Jingpin Xu, Xuejie Li, Dawei Sun, Zhenzhen Cheng, Ying Wang, Chaomin Wu, Ruiyu Wang, Jingcheng Zou, Min Yan   +15 more
doaj   +1 more source

Assessing the relationship between gut microbiota and irritable bowel syndrome: a two-sample Mendelian randomization analysis

BMC Gastroenterology, 2023
Background Growing evidence has suggested that gut microbiota is closely related to the risk of irritable bowel syndrome (IBS), but whether there is a causal effect remains unknown.
Bin Liu, D. Ye, Hong Yang, Jie Song, Xiaohui Sun, Zhixing He, Y. Mao, Gui-feng Hao   +7 more
semanticscholar   +1 more source

The Association between Circulating Lipids and Female Infertility Risk: A Univariable and Multivariable Mendelian Randomization Analysis

Nutrients, 2023
Background: Although observational studies have demonstrated that blood lipids are associated with female infertility, the causality of this association remains unclear.
Xiaoqi Zhu, X. Hong, Jingying Wu, Fanqi Zhao, Wen Wang, Lingling Huang, Jiuming Li, Bei Wang   +7 more
semanticscholar   +1 more source