Results 101 to 110 of about 8,221 (187)

Analyzing the Feasibility of Surgical Approaches to Improve Cerebral Lymphatic Circulation in Alzheimer Disease

Guoji laonian yixue zazhi
Traditionally, it was believed that the human brain lacked lymphatic vessels. However, recent studies have progressively confirmed the existence of meningeal lymphatic vessels and the glymphatic system.
Zhao Yangguang, Li Xia, Fang Yuan, Zhang Yonghong, Ren Zhenhu   +4 more
doaj   +1 more source

Perivascular Space Burden in Children With Autism Spectrum Disorder Correlates With Neurodevelopmental Severity

Journal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1496-1506, November 2025.
ABSTRACT Background Cerebral perivascular spaces (PVS) are involved in cerebrospinal fluid (CSF) circulation and clearance of metabolic waste in adult humans. A high number of PVS has been reported in autism spectrum disorder (ASD) but its relationship with CSF and disease severity is unclear.
Giulia Frigerio, Gloria Rizzato, Denis Peruzzo, Tommaso Ciceri, Elisa Mani, Fabiola Lanteri, Valentina Mariani, Massimo Molteni, Nivedita Agarwal   +8 more
wiley   +1 more source

Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

Brain Pathology, Volume 35, Issue 6, November 2025.
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li, Haiping Zhou, Jiaxin Xie, Mingjia Yu, Guanyu Ye, Yuzhen Zhang, Zhentong Li, Kunxue Zhang, Jingwen Wu, Sheng Xiao, Shuxin Zeng, Yuan Chang, Kaibin Huang, Suyue Pan   +13 more
wiley   +1 more source

Bundle structures inside the deep cervical lymphatic vessels of mice

Scientific Reports
The lymphatic system plays a crucial role in immune function and the removal of cellular waste. Recent studies have highlighted the presence of primo vessels (PVs) inside lymphatic vessels, distinct from conventional lymphatic tissues, yet their ...
Joonyoung Shin, Sungchul Kim
doaj   +1 more source

Looking at Burning Mouth Syndrome Brain: The Prevalence of Idiopathic Intracranial Hypertension Radiologic Signs in BMS Patients

Journal of Oral Rehabilitation, Volume 52, Issue 11, Page 2095-2101, November 2025.
Prevalence of radiologic signs of idiopathic intracranial hypertension in burning mouth syndrome patients. ABSTRACT Background Idiopathic intracranial hypertension (IIH), a disorder characterised by an elevation of intracranial pressure, has implications in chronic pain syndromes, especially in the cranial territory, and has been a matter of discussion.
Michele Davide Mignogna, Noemi Coppola, Stefania Leuci, Mattia Sansone, Federica Canfora, Daniela Adamo, Roberto De Simone   +6 more
wiley   +1 more source

Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD

Annals of Clinical and Translational Neurology, Volume 12, Issue 10, Page 1971-1982, October 2025.
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen   +14 more
wiley   +1 more source

재발한 만성 경막하 혈종에서 혈관 구조 변화의 조직 병리학적 평가 [PDF]

, 2021
학위논문(석사) -- 서울대학교대학원 : 융합과학기술대학원 분자의학 및 바이오제약학과, 2021.8. 김현.Chronic subdural hematoma (cSDH) is a collection of blood in subdural space with encapsulated hematoma by neomembrane. The incidence of cSDH is increasing, especially in the aging population.
김현
core  

Glymphatic and meningeal lymphatic dysfunction in Alzheimer's disease: Mechanisms and therapeutic perspectives

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by amyloid‐beta (Aβ) deposition and tau pathology. Although disease‐modifying therapies, such as anti‐Aβ monoclonal antibodies, have been approved, their clinical efficacy remains modest and accompanied by substantial safety concerns. The glymphatic system, which is a brain‐
Jiangwei Ding, Chengbin Zhao, Xiaoyan Hao, Hongliang Jiao   +3 more
wiley   +1 more source

Navigating Diagnostic Dilemmas in Cardiology: A Rare Case Report of Tuberculosis Presenting as a Cardiac Abscess

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Cardiac tuberculosis (TB) is a rare but important extrapulmonary form of TB that often presents diagnostic challenges due to nonspecific symptoms and its ability to mimic other cardiac conditions. We report the case of a 45‐year‐old woman with end‐stage renal disease secondary to granulomatosis with polyangiitis (GPA) who presented with fever ...
Fariba Bayat, Sepideh Jame Bozorgi, Mohammad Khani, Mehrdad Jafari Fesharaki, Abdoulhamid Bagheri, Elham Farahani   +5 more
wiley   +1 more source

Impaired Meningeal Lymphatic Vessel Development Worsens Stroke Outcome [PDF]

, 2020
The discovery of meningeal lymphatic vessels (LVs) has sparked interest in identifying their role in diseases of the central nervous system. Similar to peripheral LVs, meningeal LVs depend on vascular endothelial growth factor receptor-3 (VEGFR3 ...
Berndt, Marcus, Dellinger, Michael T., Hominick, Devon, Khurana, Noor, Plautz, Erik J., Poinsatte, Katherine, Stowe, Ann M., Yanev, Pavel, Zuurbier, Kielen R.   +8 more
core   +1 more source