Results 101 to 110 of about 8,481 (189)

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Deep cervical lymphatic–venous anastomosis attenuates cognitive dysfunction and biomarker abnormalities in severe Alzheimer's disease: A prospective single‐arm study

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION This study evaluated the efficacy of deep cervical lymphatic–venous anastomosis (dcLVA) for severe Alzheimer's disease (AD). METHODS A total of 139 severe AD patients undergoing dcLVA were enrolled, and changes in cognitive function and biomarkers were evaluated by comparing preoperative measures with postoperative outcomes over a
Xiaohong Fu, Jing Zhang, Qiuxia Xiao, Tingting Li, Qijun Li, Shaofu Zhang, Wen Zeng, Min Gong, Pan Cai, Zhaojian Deng, Xuan Zhang, Yuanjun Xin, Liping Su, Xiaohe Tian, Kaifeng Wu, Liulin Xiong   +15 more
wiley   +1 more source

No Glymphatic Dysfunction in Trigeminal Neuralgia: A Preliminary Study

Brain and Behavior, Volume 16, Issue 2, February 2026.
In this study investigating cross‐sectional and longitudinal DTI‐ALPS changes in patients with trigeminal neuralgia, no DTI‐ALPS alterations were detected in trigeminal neuralgia patients. ABSTRACT Background Trigeminal neuralgia (TN) patients are at risk for glymphatic dysfunction due to their prolonged headaches and sleep disturbances.
Barış Genç, Kerim Aslan
wiley   +1 more source

LRP4+ Astrocytes: A Unique Subpopulation Crucial for Blood Vessel Maintenance and Function in the Somatosensory Cortex of Normal and 5xFAD Mice

Glia, Volume 74, Issue 2, February 2026.
Lrp4+ astrocytes, uniquely vessel‐associated and GFAP−, are enriched in the pia. They support laminin‐α5+ basement membrane assembly and regulate vessel diameter and blood flow. They are reduced in 5xFAD brains, and their ablation worsens both vascular and Aβ pathology.
Emily Arzola, Gefei Yu, Lei Xiong, Daehoon Lee, Anika Wu, Shriya Paruchuri, Jasmine Skinner, Minghui Wang, Bin Zhang, Lin Mei, Wen‐Cheng Xiong   +10 more
wiley   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

재발한 만성 경막하 혈종에서 혈관 구조 변화의 조직 병리학적 평가 [PDF]

, 2021
학위논문(석사) -- 서울대학교대학원 : 융합과학기술대학원 분자의학 및 바이오제약학과, 2021.8. 김현.Chronic subdural hematoma (cSDH) is a collection of blood in subdural space with encapsulated hematoma by neomembrane. The incidence of cSDH is increasing, especially in the aging population.
김현
core  

Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeling

Journal of Neuroinflammation
Background Meningeal lymphatic vessels (mLVs) play a critical role in clearing erythrocytes from the subarachnoid space and immune cells from the brain parenchyma following subarachnoid hemorrhage (SAH). However, the drainage function of mLVs is impaired
Bingrui Zhu, Changming Liu, Ming Luo, Jiarui Chen, Sixuan Tian, Tiantong Zhan, Yibo Liu, Haocheng Zhang, Zhen Wang, Jianmin Zhang, Yuanjian Fang, Sheng Chen, Xiaoyu Wang   +12 more
doaj   +1 more source

Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice. [PDF]

J Clin Invest, 2023
Matrongolo MJ, Ang PS, Wu J, Jain A, Thackray JK, Reddy A, Sung CC, Barbet G, Hong YK, Tischfield MA.   +9 more
europepmc   +1 more source

Magnetic Resonance Imaging and Histopathological Visualization of Human Dural Lymphatic Vessels

Bio-Protocol, 2018
In this protocol, we describe a method to visualize and map dural lymphatic vessels in-vivo using magnetic resonance imaging (MRI) and ex-vivo using histopathological techniques.
Seung-Kwon Ha, Govind Nair, Martina Absinta, Nicholas Luciano, Daniel Reich   +4 more
doaj   +1 more source