Results 111 to 120 of about 11,103 (274)

The clinical question of mepolizumab in the long-term treatment of idiopathic chronic eosinophilic pneumonia; how long should we use mepolizumab?

Respiratory Medicine Case Reports
The efficacy of mepolizumab as an alternative to glucocorticoids for treating idiopathic chronic eosinophilic pneumonia (ICEP) has been reported. However, various questions remain unanswered, such as the most appropriate dose and dosage interval of ...
Masamitsu Hamakawa, Machiko Arita, Hiroshi Takahashi, Akihiko Amano, Nobuyoshi Hamao, Ayaka Tanaka, Akihiro Ito, Tadashi Ishida   +7 more
doaj  

Effective treatment with mepolizumab in a patient with severe eosinophilic granulomatosis with polyangiitis complicated with small intestine perforation

Respiratory Medicine Case Reports, 2023
Eosinophilic granulomatosis with polyangiitis (EGPA) is systemic vasculitis caused by eosinophilia affecting small to medium-sized blood vessels, which damages the organs.
Mari Sato, Masakiyo Yatomi, Ikuo Wakamatsu, Shogo Uno, Chiharu Hanazato, Tomomi Masuda, Koichi Yamaguchi, Haruka Aoki-Saito, Norimitsu Kasahara, Yosuke Miura, Hiroaki Tsurumaki, Kenichiro Hara, Yasuhiko Koga, Noriaki Sunaga, Takuhisa Okada, Hayato Ikota, Takeshi Hisada, Toshitaka Maeno   +17 more
doaj  

Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys [PDF]

, 2001
Timothy K. Hart, Richard M. Cook, Parnian Zia‐Amirhosseini, Elisabeth A. Minthorn, Teresa S. Sellers, Beverly E. Maleeff, Scot Eustis, Lester W. Schwartz, Ping Tsui, Edward R. Appelbaum, Elise C. Martin, Peter J. Bugelski, Danuta J. Herzyk   +12 more
openalex   +1 more source

Distinct Airway Inflammatory Pathways Associated with Asthma Exacerbations are Modulated by Mepolizumab Therapy in Children [PDF]

, 2022
Rationale: Identification of specific airway inflammatory pathways can lead to effective personalized treatment with biologics in asthma and insights to mechanisms of action.
Altman, Matthew, Bacharier, Leonard, Becker, Patrice, Busse, William, Gergen, Peter, Gern, James, Gill, Michelle, Gruchalla, Rebecca, Jackson, Daniel, Kattan, Meyer, Khurana Hershey, Gurjit, Liu, Andrew, Lovinsky-Desir, Stephanie, O, George, Rivera-Spoljaric, Katherine, Robison, Rachel, Sherenian, Michael, Sorkness, Christine, Stokes, Jeffrey, Teach, Stephen, Villarreal, Miguel, Visness, Cynthia, Zoratti, Edward M   +22 more
core   +1 more source

Anti–interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes☆ [PDF]

, 2004
Jennifer K. Garrett, Sean C. Jameson, Blythe Thomson, Margaret H. Collins, Lynne E. Wagoner, Debbie K Freese, Lisa A. Beck, Joshua A. Boyce, Alexandra H. Filipovich, Joyce Villanueva   +9 more
openalex   +1 more source

Mepolizumab and COPD in Real Life

Open Respiratory Archives, 2022
Fernando Revuelta-Salgado, Ascensión Hernando-Sanz, Carlos Melero-Moreno, Rocío Magdalena Díaz-Campos   +3 more
openaire   +4 more sources

Real-World Reductions in Oral Corticosteroid Use in the USA Following Mepolizumab Therapy for Severe Asthma

Journal of Asthma and Allergy, 2020
Jared Silver,1 Michael Bogart,1 Elizabeth Packnett,2 Juan Wu,2 Donna McMorrow,2 Beth Hahn1 1US Medical Affairs, GSK, Research Triangle Park, NC, USA; 2Life Sciences, IBM Watson Health, Bethesda, MD, USACorrespondence: Beth Hahn Email beth.a.hahn@gsk ...
Silver J, Bogart M, Packnett E, Wu J, McMorrow D, Hahn B   +5 more
doaj  

Real-World Experience on the Use of Mepolizumab from the Severe Asthma Registry of the German Asthma Net (MepoGAN-Study)

Journal of Asthma and Allergy, 2023
Stephanie Korn,1 Katrin Milger,2 Dirk Skowasch,3 Christian Schulz,4 Cordula Mohrlang,5 Martin Wernitz,5 Thomas Paulsson,6 Michael Hennig,5 Roland Buhl7 1IKF Pneumologie Mainz, Mainz and Thoraxklinik Heidelberg, Heidelberg, Germany; 2Department of ...
Korn S, Milger K, Skowasch D, Schulz C, Mohrlang C, Wernitz M, Paulsson T, Hennig M, Buhl R   +8 more
doaj  

Mepolizumab, a Humanized Monoclonal Antibody to IL-5, for Severe Eosinophilic Esophagitis in Adults: A Randomized, Placebo-Controlled Double-Blind Trial [PDF]

, 2007
Alex Straumann, Sébastien Conus, Hans‐Uwe Simon, Hirohito Kita, G M Kephart, Christian Bussmann, Christoph Beglinger, Jessal J. Patel, Mitchell K. Byrne   +8 more
openalex   +1 more source

Mepolizumab for the Treatment of Eosinophilic Cystitis: Reply

Journal of Investigational Allergology and Clinical Immunology
International ...
Trefond, Ludovic, Kahn, Je
openaire   +3 more sources