Results 1 to 10 of about 350 (124)

Corrigendum: Mequindox Induced Genotoxicity and Carcinogenicity in Mice [PDF]

open access: yesFrontiers in Pharmacology, 2018
[This corrects the article DOI: 10.3389/fphar.2018.00361.].
Qianying Liu   +14 more
doaj   +6 more sources

Mequindox Induced Genotoxicity and Carcinogenicity in Mice [PDF]

open access: yesFrontiers in Pharmacology, 2018
Mequindox (MEQ), acting as an inhibitor of deoxyribonucleic acid (DNA) synthesis, is a synthetic heterocyclic N-oxides. To investigate the potential carcinogenicity of MEQ, four groups of Kun-Ming (KM) mice (50 mice/sex/group) were fed with diets ...
Qianying Liu   +14 more
doaj   +5 more sources

Metabolism Profile of Mequindox in Sea Cucumbers In Vivo Using LC-HRMS [PDF]

open access: yesAntibiotics, 2022
In this work, the metabolism behavior of mequindox (MEQ) in sea cucumber in vivo was investigated using LC-HRMS. In total, nine metabolites were detected and identified as well as the precursor in sea cucumber tissues.
Xin Mao   +8 more
doaj   +3 more sources

The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats [PDF]

open access: yesFrontiers in Pharmacology, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), has been extensively used as a synthetic antibacterial agent. To evaluate the reproductive toxicity of MEQ, different concentrations of MEQ were administered to Wistar rats by feeding diets ...
Qianying Liu   +12 more
doaj   +3 more sources

Corrigendum: The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats [PDF]

open access: yesFrontiers in Pharmacology, 2018
[This corrects the article DOI: 10.3389/fphar.2018.00870.].
Qianying Liu   +12 more
doaj   +3 more sources

Mechanisms of the Testis Toxicity Induced by Chronic Exposure to Mequindox [PDF]

open access: yesFrontiers in Pharmacology, 2017
Mequindox (MEQ) is a synthetic antimicrobial agent widely used in China since the 1980s. Although the toxicity of MEQ is well recognized, its testis toxicity has not been adequately investigated.
Qianying Liu   +9 more
doaj   +3 more sources

UPLC-MS/MS Method for Simultaneous Determination of Three Major Metabolites of Mequindox in Holothurian [PDF]

open access: yesJournal of Analytical Methods in Chemistry, 2018
This study developed an ultraperformance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the detection of three major metabolites of mequindox, including 3-methyl-quinoxaline-2-carboxylic acid, 1-desoxymequindox, and 1,4 ...
Huihui Liu   +9 more
doaj   +3 more sources

Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse [PDF]

open access: yesFrontiers in Pharmacology, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), is a synthetic antimicrobial agent widely used in China. Previous studies found that the kidney was one of the main toxic target organs of the QdNOs.
Qianying Liu   +16 more
doaj   +3 more sources

Effects of lactobacillus plantarum ZJ316 on pig growth and pork quality [PDF]

open access: yesBMC Veterinary Research, 2012
Background Lactobacillus plantarum is a plant-associated bacterial species but it has also been found in human, mouse and porcine gastrointestinal tracts.
Suo Cheng   +6 more
doaj   +5 more sources

Natural occurrences and characterization of Elizabethkingia miricola infection in cultured bullfrogs (Rana catesbeiana) [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionThe bacterium Elizabethkingia miricola is a multispecies pathogen associated with meningitis-like disease that has been isolated from several amphibian species, including the bullfrog, but this is the first isolation in Guangxi.
Dongdong Wei   +14 more
doaj   +2 more sources

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