Results 21 to 30 of about 403 (128)

Molecular characterization of the tet (M)-carrying transposon Tn7124 and plasmids in Escherichia coli isolates recovered from swine. [PDF]

Front Vet Sci
Here, we report the genetic features and evolutionary mechanisms of two tet (M)-bearing plasmids (pTA2 and pTA7) recovered from swine Escherichia coli isolates.
Liu Y, Qiao Z, Ma Y, Wang M, Hu G, Li E.
europepmc   +3 more sources

Study of transport, tissue distribution, depletion, and hepatotoxicity of Cyadox, a quinoxaline-1,4-dioxide derivative. [PDF]

Front Pharmacol
BackgroundCyadox (CYA) is a derivative of quinoxaline 1,4-dioxide and a safe and effective synthetic antibacterial agent.ObjectiveThis study aimed to explore the drug transport in blood, distribution, depletion and hepatotoxicity of drugs in animals ...
Tao Z, Li C, Zhang A, Zhang Z, Huang J, Harnud S.   +5 more
europepmc   +3 more sources

In vitro antimicrobial activities of animal-used quinoxaline 1,4-di-N-oxides against mycobacteria, mycoplasma and fungi. [PDF]

BMC Vet Res, 2016
Zhao Y, Cheng G, Hao H, Hao H, Pan Y, Liu Z, Dai M, Yuan Z.   +7 more
europepmc   +2 more sources

Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro. [PDF]

Oxid Med Cell Longev, 2020
Olaquindox (OLA), a member of the quinoxaline‐N,N‐dioxide family, has been widely used as a growth‐promoting feed additive and treatment for bacterial infections. The toxicity has been a major concern, and the precise molecular mechanism remains poorly understood. The present study was aimed at investigating the roles of oxidative stress and p53 in OLA‐
Li D, Pei X, Qin X, Liu X, Li C, Li L, Dai C, Xiao X, Tang S.   +8 more
europepmc   +2 more sources

Determination of Residues of two Aminoglycoside antibiotics and five Quinololine antibiotics and Their Metabolites in Penaeus vannamei by Ultra High Performance Liquid Chromatography Tandem Mass Spectrometry [PDF]

E3S Web of Conferences, 2020
An ultra performance liquid chromatography – electrospray ionization triple-quadruple tandem mass spectrometric(UPLC–ESI MS /MS) method was developed for determining Quinololine antibiotics (Carbadox,, Quinocetone, Mequindox, Olaquindox, Cyadox ...
Zha Yu-bing, Yang Chun-liang, Lv Yi-zhi, Ye Jian-zhi, Zeng Shao-dong, Wang Xiao-fang, Deng Xiao-hong, Ma Hui-fang, Pan Xiaowei, Lin Li-yun   +9 more
doaj   +1 more source

Evaluation of the metabolomic profile through 1H-NMR spectroscopy in ewes affected by postpartum hyperketonemia [PDF]

, 2022
Ketosis is one of the most important health problems in dairy sheep. The aim of this study was to evaluate the metabolic alterations in hyperketonemic (HYK) ewes. Forty-six adult Sardinian ewes were enrolled between 7 +/- 3 days post-partum.
Faillace, Vanessa, Fiore, Enrico, Fiore, Filippo, Harvatine, Kevin, Laghi, Luca, Lisuzzo, Anastasia, Mazzotta, Elisa, Moscati, Livia, Spissu, Nicoletta, Zhu, Chenglin   +9 more
core   +2 more sources

Metabolism of mequindox in liver microsomes of rats, chicken and pigs.

Rapid Communications in Mass Spectrometry, 2010
Abstract Mequindox, 3‐methyl‐2‐quinoxalinacetyl‐1,4‐dioxide, is a quinoxaline‐ N , N ‐dioxide used in veterinary medicine as a antibacterial in China.
Zhaoying Liu, Ling-Li Huang, Dongmei Chen, Zonghui Yuan   +3 more
semanticscholar   +3 more sources

A Milk Extracellular Vesicle-Based Nanoplatform Enhances Combination Therapy Against Multidrug-Resistant Bacterial Infections. [PDF]

Adv Sci (Weinh)
Treating multidrug‐resistant bacteria with a single antibiotic is becoming increasingly difficult, leading to a gradual rise in global infections and deaths. Here, a bio‐inspired delivery system equipped with combination therapy and paracellular transport has been proven to deliver and slowly release a combination of drugs through oral administration ...
Qu S, Yang S, Xu Q, Zhang M, Gao F, Wu Y, Li L.   +6 more
europepmc   +2 more sources

Contribution of different mechanisms to Ciprofloxacin resistance in Salmonella spp. [PDF]

, 2021
Development of fluoroquinolone resistance can involve several mechanisms that include chromosomal mutations in genes (gyrAB and parCE) encoding the target bacterial topoisomerase enzymes, increased expression of the AcrAB-TolC efflux system, and ...
Chang, Man-Xia, Jiang, Hong-Xia, Li, Rong-Sheng, Lin, Xiao-Ling, Sun, Yin-Huan, Webber, Mark A., Yang, Ling, Zhang, Jin-Fei   +7 more
core   +1 more source

Treatment of infections caused by multidrug-resistant Gram-negative bacteria:Report of the British Society for Antimicrobial Chemotherapy/Healthcare Infection Society/British Infection Association Joint Working Party [PDF]

, 2018
The Working Party makes more than 100 tabulated recommendations in antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) Gram-negative bacteria (GNB) and suggest further research, and algorithms for hospital and ...
Enoch, David A, Hawkey, Peter M, Livermore, David M, McNulty, Cliodna A M, Otter, Jonathan A, Warren, Roderic E, Wilson, A Peter R   +6 more
core   +4 more sources