Results 71 to 80 of about 98,547 (254)

Genome‐wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

open access: yesmLife, EarlyView.
Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei   +9 more
wiley   +1 more source

Antimicrobial Susceptibility Pattern of Extended-Spectrum Beta-Lactamase Producing Escherichia coli in Urinary Tract Infection [PDF]

open access: yesJournal of Sharif Medical & Dental College
Objective: To detect the frequency of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli in urinary tract infection and also determine their antibiotic susceptibility to various antimicrobials.
Tariq Hussain   +5 more
doaj  

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

open access: yesVIEW, EarlyView.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang   +9 more
wiley   +1 more source

Clinical Features and Outcomes of Chronic Otitis Media Complications: A 20‐Year Retrospective Study at a Tertiary Hospital

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic otitis media (COM) is a major public health concern, particularly in developing countries. Although complications have decreased with modern antibiotics, they still cause significant morbidity and mortality. This study analyzed the clinical features, bacteriological profiles, and treatment outcomes of COM complications at a ...
Viraporn Atchariyasathian   +1 more
wiley   +1 more source

Air contamination, syringe contamination, and cross-contamination when using an automatic compounding device for sensitizing drugs

open access: yesPharmaceutical Technology in Hospital Pharmacy, 2023
To measure cross-contamination between batches of different sensitizing drugs, contamination on the outside of compounded syringes, and drug concentrations in environmental air when using an automated compounding device.
Sessink Paul   +6 more
doaj   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

open access: yesWorld Journal of Surgery, EarlyView.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock   +41 more
wiley   +1 more source

Carbapenems as Antidotes for the Management of Acute Valproic Acid Poisoning

open access: yesPharmaceuticals
Introduction: Valproic acid (VPA) is a broad-spectrum drug primarily used in the treatment of epilepsy and bipolar disorder. It is not an uncommon occurrence for VPA to cause intoxication.
Nataša Perković Vukčević   +6 more
doaj   +1 more source

Meropenem.

open access: yesIndian pediatrics, 2006
Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF penetrability and useful in treatment
Dheeraj, Shah, Manish, Narang
openaire   +1 more source

Emergence and Genomic Characterization of a Hypervirulent Klebsiella pneumoniae Isolate From a New Clone in Brazil

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Carlos Henrique Camargo   +21 more
wiley   +1 more source

Meropenem [PDF]

open access: yesReactions Weekly, 2021
openaire   +2 more sources

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