Results 61 to 70 of about 100,222 (232)

Effect of β-lactamase inhibitors on in vitro activity of β-lactam antibiotics against Burkholderia cepacia complex species [PDF]

, 2016
Background: Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients. Intrinsic resistance to a wide range of antimicrobial agents, including a variety of beta-
Coenye, Tom, Everaert, Annelien
core   +2 more sources

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan [PDF]

, 2019
Objective: To study the prevelence of antibiotic resistance and the prevalent bacterial isolates in hospitalized patients in Khartoum hospitals. Materials & Methods: A cross-sectional prevalence study was carried out during the period of April ...
Abdalrahman, Ihab B, Al-Hassan, Leena, El Amin, Nagwa M, Osman, Einas A   +3 more
core   +4 more sources

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

Veterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan, Nicola Williams, Jenny Llewelyn, Sam Haldenby, Gina Pinchbeck, Dorina Timofte   +5 more
wiley   +1 more source

Prevalence and Predictors of Urinary Tract Infection and Severe Malaria Among Febrile Children Attending Makongoro Health Centre in Mwanza City, North-Western Tanzania. [PDF]

, 2012
In malaria endemic areas, fever has been used as an entry point for presumptive treatment of malaria. At present, the decrease in malaria transmission in Africa implies an increase in febrile illnesses related to other causes among underfives.
A Dzeing-Ella, A Rougemont, B Murray, BHM Wolf, BO Olaleye, CA Guerra, CLSI, D Chandramohan, D De Savigny, E Festo, F Font, FN Okwara, G Raso, GO Akpede, HD Mazigo, J Berkley, J Prada, J Richens, K Kallander, K Panaretto, L Kish, M Gorelick, MF Cotton, N Kayange, P Bahwere, P Bouvier, PW Gething, Q Bassat, RA Hoddon, Roll Back Malaria, S Gove, TJ O'Dempsey, V Batwala, V D'Acremont, World Health Organization, World Health Organization, WP O'Meara, Y Panahi   +37 more
core   +1 more source

Clinical Features and Outcomes of Chronic Otitis Media Complications: A 20‐Year Retrospective Study at a Tertiary Hospital

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic otitis media (COM) is a major public health concern, particularly in developing countries. Although complications have decreased with modern antibiotics, they still cause significant morbidity and mortality. This study analyzed the clinical features, bacteriological profiles, and treatment outcomes of COM complications at a ...
Viraporn Atchariyasathian, Nipit Tangchitnob   +1 more
wiley   +1 more source

Do We Need Meropenem Treatment Beyond 7 Days in Febrile Neutropenic Patients: A Cost-Effectiveness Analysis

Antibiotics
Background: Febrile neutropenia is a critical complication in patients with hematological malignancies; immediate initiation of empirical treatment with a broad-spectrum agent is the standard of care.
Leyla Yumrukaya, Arnold Hagens, Ahmet Çağkan İnkaya, Gökhan Metan, Maarten Postma, Selen Yeğenoğlu, Murat Akova   +6 more
doaj   +1 more source

Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]

, 2010
Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core   +2 more sources

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Allergy, EarlyView.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud, Emil M. Pallesen, Ziao Zeng, Martin R. J. Namini, Chella Krishna Vadivel, Lise Mette Rahbek Gjerdrum, Lang Yan, Sana Ahmad, Lise M. Lindahl, Michael Bzorek, Maria R. Kamstrup, Saptaswa Dey, Sisse Rye Ostrowski, Erik Sørensen, Pia Rantakari, Charlotte Menne Bonefeld, Carsten Geisler, Anders Woetmann, Riitta Lahesmaa, Lars Iversen, Peter Wolf, Thomas Litman, Terkild B. Buus, Niels Ødum   +23 more
wiley   +1 more source

In Vitro Evaluation of Antimicrobial Synergy Against Multidrug-Resistant Gram-Negative Paediatric Bloodstream Pathogens in South Africa

Antibiotics
Background: In vitro synergy testing (ST) is a useful means to gauge the performance ofantibiotic combinations against multidrug-resistant (MDR) Gram-negative bacteria (GNB).
Prenika Jaglal, Sithembiso Christopher Velaphi, Colin Nigel Menezes, Khine Swe Swe-Han   +3 more
doaj   +1 more source