Results 41 to 50 of about 89,290 (238)

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Exogenous glutathione reverses meropenem resistance in carbapenem-resistant Klebsiella pneumoniae

Frontiers in Pharmacology, 2023
Background: The rate of carbapenem-resistant Klebsiella pneumoniae (CRKP) infection has been increasing rapidly worldwide and, poses a significant risk to human health.
Juan Yi, Juan Yi, Chao Liu, Chao Liu, Ping Yang, Ping Yang, Zhen-chao Wu, Zhen-chao Wu, Chun-jing Du, Chun-jing Du, Ning Shen, Ning Shen, Ning Shen, Ning Shen   +13 more
doaj   +1 more source

Comparison of Pharmaceutical Characteristics between Brand-Name Meropenem and Its Generics

Antibiotics, 2021
This study aimed to provide comparative information of pharmaceutical properties, including particle morphology and distribution uniformity, solubility, presence of residual solvent and insoluble particles, and antimicrobial activities, between brand ...
Ping Yang, Shigeru Fujimura, Yawei Du, Bei Zhang, Li Yang, Masato Kawamura, Zhenhua Zhang, Suodi Zhai   +7 more
doaj   +1 more source

Outcomes and Predictors of Mortality in Patients With KPC-Kp Infections Treated With Meropenem Vaborbactam: An Observational Multicenter Study

Open Forum Infectious Diseases
Background Meropenem-vaborbactam is a recent and promising option for the treatment of KPC-producing Klebsiella pneumoniae (KPC-Kp) infections, including those resistant to ceftazidime-avibactam.
M. Tumbarello, F. Raffaelli, M. Giannella, G. De Pascale, A. Cascio, F. D. De Rosa, A. Cattelan, A. Oliva, A. Saracino, M. Bassetti, C. Mussini, Roberto Luzzati, Alessandro Capone, Liana Signorini, Michele Bartoletti, M. Sambo, L. Sarmati, S. Antinori, A. Mularoni, C. Tascini, Alberto Corona, R. Pascale, R. Rubino, S. Corcione, M. Mazzitelli, G. Giuliano, Antonio Lovecchio, D. Bavaro, M. Meschiari, F. Montagnani, M. Fabbiani, I. De Benedetto, M. Antonelli, M. Venditti, P. Viale   +34 more
semanticscholar   +1 more source

Increasing frequency of OXA-48-producing Enterobacterales worldwide and activity of ceftazidime/avibactam, meropenem/vaborbactam and comparators against these isolates

Journal of Antimicrobial Chemotherapy, 2021
Objectives To investigate the increase in the rates of OXA-48-like-producing isolates during 3 years of global surveillance. Methods Among 55?>162 Enterobacterales isolates, 354 carbapenem-resistant isolates carried genes encoding OXA-48-like enzymes ...
M. Castanheira, Timothy B Doyle, T. Collingsworth, H. Sader, R. Mendes   +4 more
semanticscholar   +1 more source

Emergence of Carbapenem Resistant Non-Fermenting Gram-Negative Bacilli Isolated in an Icu of a Tertiary Care Hospital [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: The emergence and spread of Multi-Drug Resistant (MDR) Non-Fermenting Gram-Negative Bacilli (NFGNB) in Intensive Care Units (ICU) and their genetic potential to transmit diverse antibiotic resistance regardless of their ability to ...
Sonika Agarwal, Barnali Kakati, Sushant Khanduri, Shalini Gupta   +3 more
doaj   +1 more source

Meropenem Administered via Intravenous Regional Limb Perfusion for Orthopedic Sepsis in Horses: A Clinical Retrospective Study

Frontiers in Veterinary Science, 2021
Septic synovitis is a critical orthopedic condition in horses. Early intervention is key, with antibiotic therapy typically initiated prior to culture and susceptibility reports becoming available.
Allison P. Mosichuk, Joseph S. Smith, Joseph S. Smith, Dane M. Tatarniuk, Jarrod R. Troy, Amanda J. Kreuder   +5 more
doaj   +1 more source

Construction and validation of a meropenem-induced liver injury risk prediction model: a multicenter case-control study

Frontiers in Pharmacology
ObjectiveTo construct and validate a risk prediction model for patients with meropenem-induced liver injury (MiLI).MethodsA retrospective case-control study was conducted to collect data on inpatients treated with meropenem at Shiyan People’s Hospital ...
Yan He, Yan He, Hongqin Ke, Jianyong Zhu, Xin Yuan, Hongliang Li, Hongliang Li, Wenwen Wu, Shuman Yang, Shuman Yang, Huibin Yu, Huibin Yu   +11 more
doaj   +1 more source

Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

Infectious Disease and Therapy, 2018
IntroductionTreatment options for carbapenem-resistant Enterobacteriaceae (CRE) infections are limited and CRE infections remain associated with high clinical failure and mortality rates, particularly in vulnerable patient populations.
R. Wunderink, E. Giamarellos‐Bourboulis, G. Rahav, A. Mathers, M. Bassetti, J. Vázquez, O. Cornely, J. Solomkin, T. Bhowmick, J. Bishara, G. Daikos, Tim Felton, M. J. L. Furst, E. Kwak, F. Menichetti, I. Oren, E. Alexander, David A Griffith, O. Lomovskaya, J. Loutit, Shu Zhang, M. Dudley, K. Kaye   +22 more
semanticscholar   +1 more source

Meropenem/vaborbactam: a next generation β-lactam β-lactamase inhibitor combination

Expert Review of Anti-Infective Therapy, 2020
Introduction infections due to carbapenem-resistant Enterobacterales (CRE) constitute a worldwide threat and are associated with significant mortality, especially in fragile patients, and costs.
A. Novelli, Paola Del Giacomo, G. Rossolini, M. Tumbarello   +3 more
semanticscholar   +1 more source