Results 31 to 40 of about 100,222 (232)

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]

, 2018
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M., Bethel, Christopher R., Bonomo, Robert A., Giannini, Estefanía, Klinke, Sebastian, Llarrull, Leticia Irene, Mojica, María F., Otero, Lisandro Horacio, Palacios, Antonela Rocio, Taracila, Magdalena A., Vila, Alejandro Jose   +10 more
core   +1 more source

Comparison of Pharmaceutical Characteristics between Brand-Name Meropenem and Its Generics

Antibiotics, 2021
This study aimed to provide comparative information of pharmaceutical properties, including particle morphology and distribution uniformity, solubility, presence of residual solvent and insoluble particles, and antimicrobial activities, between brand ...
Ping Yang, Shigeru Fujimura, Yawei Du, Bei Zhang, Li Yang, Masato Kawamura, Zhenhua Zhang, Suodi Zhai   +7 more
doaj   +1 more source

Open conversion after aortic endograft infection. Caused by colistin-resistant, carbapenemase-producing Klebsiella pneumoniae [PDF]

, 2016
A 62-year-old man presented with fever, abdominal pain, and malaise 13 months after emergency endovascular aortic repair. Computed tomographic angiograms showed a periprosthetic fluid and gas collection, so infection was diagnosed. Open conversion was
Capoccia, Laura, Mansour, WASSIM AHMAD, Menna, Danilo, Montelione, Nunzio, Sirignano, Pasqualino, Speziale, Francesco   +5 more
core   +1 more source

Emergence of Carbapenem Resistant Non-Fermenting Gram-Negative Bacilli Isolated in an Icu of a Tertiary Care Hospital [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: The emergence and spread of Multi-Drug Resistant (MDR) Non-Fermenting Gram-Negative Bacilli (NFGNB) in Intensive Care Units (ICU) and their genetic potential to transmit diverse antibiotic resistance regardless of their ability to ...
Sonika Agarwal, Barnali Kakati, Sushant Khanduri, Shalini Gupta   +3 more
doaj   +1 more source

Meropenem Administered via Intravenous Regional Limb Perfusion for Orthopedic Sepsis in Horses: A Clinical Retrospective Study

Frontiers in Veterinary Science, 2021
Septic synovitis is a critical orthopedic condition in horses. Early intervention is key, with antibiotic therapy typically initiated prior to culture and susceptibility reports becoming available.
Allison P. Mosichuk, Joseph S. Smith, Joseph S. Smith, Dane M. Tatarniuk, Jarrod R. Troy, Amanda J. Kreuder   +5 more
doaj   +1 more source

Construction and validation of a meropenem-induced liver injury risk prediction model: a multicenter case-control study

Frontiers in Pharmacology
ObjectiveTo construct and validate a risk prediction model for patients with meropenem-induced liver injury (MiLI).MethodsA retrospective case-control study was conducted to collect data on inpatients treated with meropenem at Shiyan People’s Hospital ...
Yan He, Yan He, Hongqin Ke, Jianyong Zhu, Xin Yuan, Hongliang Li, Hongliang Li, Wenwen Wu, Shuman Yang, Shuman Yang, Huibin Yu, Huibin Yu   +11 more
doaj   +1 more source

Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]

, 2016
Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA, D'ABRAMO, ALESSANDRA, DE ANGELIS, Massimiliano, Favaro, Marco, Ferretti, Giancarlo, GIZZI, FRANCESCA, IANNETTA, MARCO, MASCELLINO, Maria Teresa, MASTROIANNI, Claudio Maria, OLIVA, ALESSANDRA, RUSSO, Gianluca, VULLO, Vincenzo   +11 more
core   +1 more source

Meropenem

Revista de Medicina de la Universidad de Navarra, 2017
M, Escolar, J, Honorato
  +8 more sources

Synergistic effect and antibiofilm activity of the antimicrobial peptide K11 with conventional antibiotics against multidrug-resistant and extensively drug-resistant Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionInfections caused by drug-resistant Klebsiella pneumoniae are now a serious problem for public health, associated with high morbidity and mortality due to limited treatment options.
Chawalit Chatupheeraphat, Jiratchaya Peamchai, Sirirat Luk-in, Warawan Eiamphungporn   +3 more
doaj   +1 more source

Extended Infusions of Meropenem for Febrile Neutropenia [PDF]

, 2019
Background: Neutropenic fever is an oncologic emergency that requires quick intervention with anti-pseudomonal beta-lactam antibiotics, such as meropenem.
Przybylski, PharmD, Daniel J, Reeves, PharmD, BCOP, David J   +1 more
core   +1 more source