Results 71 to 80 of about 373,900 (338)
Advanced Science, EarlyView.Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang +12 more
wiley +1 more source
Prospects for a MERS-CoV spike vaccine
Expert Review of Vaccines, 2018 Introduction: Six years have passed since Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV), a newly emerging infectious virus, was first reported in 2012.
Yusen Zhou, Shibo Jiang, Lanying Du
doaj +1 more source
Middle East respiratory syndrome coronavirus in the last two years: Health care workers still at risk [PDF]
, 2019 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core +1 more source
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, EarlyView.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Convalescent Plasma Therapy for COVID-19: Lessons from SARS-CoV, MERS-CoV, and H1N1 Infection
Acta Medica Indonesiana, 2021 The global widespread mortality after the emergence of SARS-CoV-2 infection in China, has become a critical concern all around the world. Convalescent plasma (CP) therapy is one of the methods elevating the survival rate for COVID-19 infection cases ...
Parastoo Hosseini +8 more
doaj
Anthropen, 2018 Comment la mer pourrait-elle constituer un "objet" anthropologique? Quelles différences de traitements et d'analyses a-t-elle stimulée? Et pourquoi est-elle passée en quelques décennies de la périphérie vers le cœur des sciences humaines?
openaire +1 more source
Nytt Norsk Tidsskrift, 2020 Hvilke konsekvenser får det når innvandringspolitikken preges av stadig mer midlertidighet? Dette spørsmålet ble ikke utredet og knapt diskutert i forbindelse med omfattende politiske endringer etter asylforliket. Denne artikkelen setter søkelys på midlertidighetens konsekvenser for individet og for samfunnsmessige målsetninger om integrering.
Eggebø, Helga, Staver, Anne Balke
openaire +3 more sources
Advanced Science, EarlyView.CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal +3 more
wiley +1 more source
Advanced Science, EarlyView.These findings elucidated the crucial role of the “SVs‐3D genome remodeling‐epigenetic modifications‐gene expression” cascade regulatory network in cotton fiber domestication, offering both a theoretical foundation and genetic resources for molecular design breeding in fiber crops.
Lei Shao +11 more
wiley +1 more source
Robust $$k$$ k -mer frequency estimation using gapped $$k$$ k -mers [PDF]
Journal of Mathematical Biology, 2013 Oligomers of fixed length, k, commonly known as k-mers, are often used as fundamental elements in the description of DNA sequence features of diverse biological function, or as intermediate elements in the constuction of more complex descriptors of sequence features such as position weight matrices.
Ghandi, Mahmoud +2 more
openaire +3 more sources