Results 81 to 90 of about 475,573 (366)
FEBS Open Bio, EarlyView.Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper +5 more
wiley +1 more source
Mathematical Biosciences and Engineering, 2020 During the earliest stages of a pandemic, mathematical models are a tool that can be imple-mented quickly. However, such models are based on meagre data and limited biological understanding.
Christian Costris-Vas +2 more
doaj +1 more source
Product of natural evolution (SARS, MERS, and SARS-CoV-2); deadly diseases, from SARS to SARS-CoV-2
Human Vaccines & Immunotherapeutics, 2021 SARS-CoV-2, the virus causing COVID-19, is a single-stranded RNA virus belonging to the order Nidovirales, family Coronaviridae, and subfamily Coronavirinae.
Mohamad Hesam Shahrajabian +2 more
doaj +1 more source
The middle east respiratory syndrome coronavirus respiratory infection: an emerging infection from the arabian peninsula [PDF]
, 2016 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, J. A., Memish, Ziad A.
core +1 more source
Journal of Virology, 2020 The bifunctional nsp14 subunit of the coronavirus replicase contains 3′-to-5′ exoribonuclease (ExoN) and guanine-N7-methyltransferase domains. For the betacoronaviruses MHV and SARS-CoV, ExoN was reported to promote the fidelity of genome replication ...
N. Ogando +5 more
semanticscholar +1 more source
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
Advanced Biology, EarlyView.This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer +8 more
wiley +1 more source
Dental recommendations in the COVID-19 pandemic: A narrative review
Medwave, 2020 Introduction COVID-19 is a world public health problem due to its morbidity and mortality, especially in at-risk groups. The dental environment has a high risk of viral transmission; accordingly, this study aimed to identify recommendations based on the
Juan Pablo Vargas-Buratovic +5 more
doaj +1 more source
Immunogenicity of High-Dose MVA-Based MERS Vaccine Candidate in Mice and Camels
Vaccines, 2022 The Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic pathogen that can transmit from dromedary camels to humans, causing severe pneumonia, with a 35% mortality rate.
Naif Khalaf Alharbi +11 more
doaj +1 more source
Emerging respiratory viral infections: MERS-CoV and influenza [PDF]
, 2014 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core +1 more source