Results 51 to 60 of about 13,648 (298)

Formulation and Evaluation of Enteric Coated Matrix Tablets of Mesalamine for Inflammatory Bowel Disease

Journal of Drug Delivery and Therapeutics, 2022
Mesalamine is a gold standard anti-inflammatory drug used to treat inflammatory bowel illnesses. It's usually used to treat and keep Ulcerative Colitis in remission in mild to moderate cases.
Nikita Chourey, Khushi Chouksey
semanticscholar   +1 more source

Probiotics in the treatment of diverticular disease. A systematic review [PDF]

, 2016
BACKGROUND AND AIMS: Diverticular disease is a common gastrointestinal condition. Low-grade inflammation and altered intestinal microbiota have been identified as factors contributing to abdominal symptoms.
ANNIBALE, Bruno, Bellisario, Cristina, ESPOSITO, GIANLUCA, Hassan, Cesare, LAHNER, EDITH, Zullo, Angelo   +5 more
core   +1 more source

Oral 5-Aminosalicylate, Mesalamine Suppository, and Mesalamine Enema as Initial Therapy for Ulcerative Proctitis in Clinical Practice with Quality of Care Implications

Canadian Journal of Gastroenterology and Hepatology, 2016
Background. Ulcerative proctitis (UP) is typically treated initially with oral 5-aminosalicylate (“5-ASA”), mesalamine suppository, or mesalamine enema (“UP Rx”). Little is known about their effectiveness in practice. Methods. Using a US health insurance
James M. Richter, Nabeela K. Arshi, Gerry Oster   +2 more
doaj   +1 more source

An Orally Administered Redox Nanoparticle That Accumulates in the Colonic Mucosa and Reduces Colitis in Mice [PDF]

, 2012
Background & AimsDrugs used to treat patients with ulcerative colitis are not always effective because of nonspecific distribution, metabolism in the gastrointestinal tract, and side effects. We designed a nitroxide radical-containing nanoparticle (RNPO)
Matsui Hirofumi, Nagasaki Yukio, Tomita Tsutomu, Vong Long Binh, Yoshitomi Toru, 吉冨 徹, 長崎 幸夫   +6 more
core   +1 more source

Fecal Microbial Transplantation versus Mesalamine Enema for Treatment of Active Left-Sided Ulcerative Colitis—Results of a Randomized Controlled Trial

Journal of Clinical Medicine, 2021
Background and Aims: Ulcerative colitis (UC) is a chronic inflammatory disease. Fecal microbial transplantation (FMT) is a promising alternative treatment.
J. Březina, L. Bajer, P. Wohl, D. Ďuricová, P. Hrabák, A. Novotný, J. Koželuhová, M. Lukáš, J. Mrázek, K. Fliegerová, S. Kvasnová, Mekadim Chahrazed, J. Mareš, J. Spicak, P. Drastich   +14 more
semanticscholar   +1 more source

Myocarditis Secondary to Mesalamine-Induced Cardiotoxicity in a Patient with Ulcerative Colitis

Case Reports in Medicine, 2018
Development of cardiac manifestations in patients diagnosed with inflammatory bowel disease undergoing treatment with mesalamine is a rare. When this occurs, it can be difficult to tease out the primary etiology, as both IBD and mesalamine can cause ...
Kelechukwu U. Okoro, Matthew D. Roby, Adegbenga A. Bankole   +2 more
doaj   +1 more source

Design and Characterization of Mesalamine Loaded Nanoparticles for Controlled Delivery System [PDF]

Nanomedicine Research Journal, 2016
Objective(s): Nanoparticles (NPs) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects.
Simin Seifirad, Hasan Karami, Shadab Shahsavari, Farzad Mirabasi, Farid Dorkoosh   +4 more
doaj   +1 more source

Release of 5-Aminosalicylic Acid (5-ASA) from Mesalamine Formulations at Various pH Levels [PDF]

, 2015
INTRODUCTION: Oral formulations of 5-aminosalicylic acid (5-ASA) for treatment of ulcerative colitis have been developed to minimize absorption prior to the drug reaching the colon.
Adeyinka Abinusawa, Srini Tenjarla
core   +1 more source

One of the 5-aminosalicylates drug, mesalamine as a drug repurposing lead against breast cancer

Bulletin of the National Research Centre, 2022
Background Breast cancer is the world's second leading cause of death in women. The problem of chemoresistance in breast cancer is proving to be a challenge for researchers and several oncologists all around the world.
Dayanand Swami, Shafina Siddiqui, Urwashi Kumar, Shine Devarajan, Jyotirmoi Aich   +4 more
doaj   +1 more source

pH-Sensitive Hydrogels Fabricated with Hyaluronic Acid as a Polymer for Site-Specific Delivery of Mesalamine

ACS Omega
Hydrogels with the main objective of releasing mesalamine (5-aminosalicylic acid) in the colon in a modified manner were formulated in the present work using a free-radical polymerization approach.
Huma Liaqat, Syed Faisal Badshah, M. Minhas, Kashif Barkat, S. A. Khan, Muhammad Delwar Hussain, Mohsin Kazi   +6 more
semanticscholar   +1 more source