Results 51 to 60 of about 7,348 (201)

Patient considerations in the management of ulcerative colitis: role of once-daily MMX mesalamine

open access: yesPatient Preference and Adherence, 2009
Daniel B Zandman, Mark A PeppercornHarvard Medical School, Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USAAbstract: Mesalamine and its derivatives are effective and well-tolerated therapies for ...
Daniel B Zandman, Mark A Peppercorn
doaj  

Water-in-Water Emulsion as a New Approach to Produce Mesalamine-Loaded Xylan-Based Microparticles

open access: yesApplied Sciences, 2019
The water-in-water emulsion method has been reported as a technique able to prepare microparticles without using harmful solvents. However, there are few reports showing the encapsulation of small molecules into microparticles produced within this ...
Bartolomeu S. Souza   +6 more
doaj   +1 more source

The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin

open access: yesmSphere, 2020
Colibactin induces DNA damage in mammalian cells and has been linked to the virulence of Escherichia coli and the promotion of colorectal cancer (CRC). By looking for mutants attenuated in the promoter activity of clbB encoding one of the key enzymes for
Min Tang-Fichaux   +5 more
doaj   +1 more source

Effect of Intestinal Microbiota Transplantation on Intestinal Flora and Inflammatory Factor Levels in Patients with Ulcerative Colitis

open access: yesInfection and Drug Resistance, 2023
Zhi Wang,1,* Li Yang,2,* Shan Sun2 1Pediatric Gastrointestinal Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, People’s Republic of China; 2Gastroenterology, Sinopharm Dongfeng General Hospital, Hubei ...
Wang Z, Yang L, Sun S
doaj  

Impact of biologic induction dose and concomitant drugs on anti‐drug antibody formation in a pediatric IBD cohort with high Hispanic representation

open access: yesJPGN Reports, Volume 6, Issue 4, Page 437-443, November 2025.
Abstract Objectives The use of biologic therapy is increasing in pediatric patients with inflammatory bowel disease (IBD). However, efficacy may be compromised by increased drug clearance and anti‐drug antibodies (ADAs). Historically, concomitant immunomodulator therapy (CIT) has been used to prevent ADA formation. Pediatric studies evaluating CIT have
Kenneth Grant   +3 more
wiley   +1 more source

Determination of Mesalamine Related Impurities from Drug Product by Reversed Phase Validated UPLC Method

open access: yesE-Journal of Chemistry, 2011
In the present study gradient reversed-phase UPLC method was developed for simultaneous determination and separation of impurities and degradation products from drug product.
Trivedi Rakshit Kanubhai   +2 more
doaj   +1 more source

Simple and sensitive spectrophotometric methods for the analysis of mesalamine in bulk and tablet dosage forms

open access: yesQuímica Nova, 2011
Three simple, sensitive, economical and reproducible spectrophotometric methods (A, B and C) are described for determination of mesalamine in pure drug as well as in tablet dosage forms. Method A is based on the reduction of tungstate and/or molybdate in
Bala Sekaran Chandra   +5 more
doaj   +1 more source

The plot thickens: A pediatric cases series on collagenous gastritis

open access: yesJPGN Reports, Volume 6, Issue 4, Page 368-371, November 2025.
Abstract Objective Collagenous gastritis (CG) is a rare gastrointestinal disorder characterized by the deposition of collagen in the sub‐epithelium of the gastric mucosa. CG can cause a variety of symptoms including iron deficiency anemia, abdominal pain, dyspepsia, vomiting, and weight loss.
Annemarie Rompca   +3 more
wiley   +1 more source

Risk of Hemolytic Anemia in IBD Patients with Glucose-6-Phosphate Dehydrogenase Deficiency Treated with Mesalamine: Results of a Retrospective-Prospective and Ex Vivo Study [PDF]

open access: gold, 2023
Maria Pina Dore   +8 more
openalex   +1 more source

Primary Sclerosing Cholangitis Worsens Prognosis in Patients With Inflammatory Bowel Disease: A Propensity‐Matched Cohort Study

open access: yesUnited European Gastroenterology Journal, Volume 13, Issue 9, Page 1776-1786, November 2025.
ABSTRACT Background Few data are available on the impact of primary sclerosing cholangitis (PSC) on inflammatory bowel disease (IBD). Objective We conducted a retrospective study using TriNetX to compare the outcomes of patients with IBD and those with concomitant IBD and PSC.
Ferdinando D'Amico   +14 more
wiley   +1 more source

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