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Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence [PDF]

open access: yes, 2017
Multicellular spheroids are an established system for three-dimensional cell culture. Spheroids are typically generated using hanging drop or non-adherent culture; however, an emerging technique is to use magnetic levitation.
Berry, Catherine C.   +5 more
core   +10 more sources

Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review

open access: yesStem cell research & therapeutics, 2022
The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide consideration because of their immense potential for immunomodulation and their therapeutic function in tissue regeneration.
Ria Margiana   +12 more
semanticscholar   +1 more source

Mesenchymal stem cell-derived exosomes in cancer therapy resistance: recent advances and therapeutic potential

open access: yesMolecular Cancer, 2022
Mesenchymal stem cells (MSCs) are multipotent stromal cells that can be obtained from various human tissues and organs. They can differentiate into a wide range of cell types, including osteoblasts, adipocytes and chondrocytes, thus exhibiting great ...
Zhengjun Lin   +5 more
semanticscholar   +1 more source

Eph-Ephrin Signaling Mediates Cross-Talk Within the Bone Microenvironment

open access: yesFrontiers in Cell and Developmental Biology, 2021
Skeletal integrity is maintained through the tightly regulated bone remodeling process that occurs continuously throughout postnatal life to replace old bone and to repair skeletal damage. This is maintained primarily through complex interactions between
Agnieszka Arthur   +3 more
doaj   +1 more source

Effects of Mesenchymal Stem Cell-Derived Exosomes on Autoimmune Diseases

open access: yesFrontiers in Immunology, 2021
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have been demonstrated in preclinical studies and trials of inflammatory and autoimmune diseases.
Ziwei Shen   +5 more
semanticscholar   +1 more source

Advances in mesenchymal stem cell exosomes: a review

open access: yesStem cell research & therapeutics, 2021
Stem cells can be used for regenerative medicine and as treatments for disease. The application of tissue engineering-related transplantation, stem cells, and local changes in the microenvironment is expected to solve major medical problems.
Yaya Tang, Yan Zhou, Hong-jun Li
semanticscholar   +1 more source

Comparative Antimicrobial Effects of Rat Blood-derived Products and Adipose-derived Mesenchymal Stem Cell Conditioned Medium [PDF]

open access: yesResearch in Molecular Medicine, 2023
Background: The antimicrobial characteristics of biological products are fundamental in medicine due to their ability to treat microbial infections. This research aimed to assess and compare the antimicrobial properties of various platelet concentrates ...
Mohsen Sheykhhasan   +3 more
doaj  

Quercetin Application for Common Carp (Cyprinus carpio): I. Effects on Growth Performance, Humoral Immunity, Antioxidant Status, Immune-Related Genes, and Resistance against Heat Stress

open access: yesAquaculture Nutrition, 2023
This study was done to evaluate the effect of different quercetin levels on growth performance, immune responses, antioxidant status, serum biochemical factors, and high-temperature stress responses in common carp (Cyprinus carpio). A total number of 216
Kobra Armobin   +7 more
doaj   +1 more source

Allelic variation in TUSC1 gene: rs1462218557 is associated with male infertility and azoospermia

open access: yesEgyptian Journal of Medical Human Genetics, 2023
Background Male infertility is rapidly growing, and single nucleotide polymorphism (SNP) association studies are of critical importance. Tumor suppressor candidate 1 (TUSC1) gene is associated with azoospermia.
Zahra Vahidi Emami   +2 more
doaj   +1 more source

Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation

open access: yesScientific Reports, 2020
Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro   +7 more
doaj   +1 more source

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