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Stem cells have two features: the ability to differentiate along different lineages and the ability of self-renewal. Two major types of stem cells have been described, namely, embryonic stem cells and adult stem cells. Embryonic stem cells (ESC) are obtained from the inner cell mass of the blastocyst and are associated with tumorigenesis, and the use ...
Dah-Ching Ding +2 more
+8 more sources
Human mesenchymal stem cells [PDF]
AbstractMesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self‐renewal capacity, multipotency and potent immunomodulatory effects on immune cells. However, heterogeneity of MSCs has become a prominent obstacle to limit their translation into practice, as cells from different tissue sources
Xiaoyong Chen +23 more
openaire +2 more sources
Investigation of the limits of nanoscale filopodial interactions [PDF]
Mesenchymal stem cells are sensitive to changes in feature height, order and spacing. We had previously noted that there was an inverse relationship between osteoinductive potential and feature height on 15-, 55- and 90 nm-high titania nanopillars, with ...
Dalby, Matthew J. +5 more
core +10 more sources
Eph-Ephrin Signaling Mediates Cross-Talk Within the Bone Microenvironment
Skeletal integrity is maintained through the tightly regulated bone remodeling process that occurs continuously throughout postnatal life to replace old bone and to repair skeletal damage. This is maintained primarily through complex interactions between
Agnieszka Arthur +3 more
doaj +1 more source
The multipotential progenitor cells called ,Mesenchymal Stem Cells" (MSC) are capable of differrentiation at least into bone, cartilage, and adipose tissues. The commonly recognized role of these cells is the formation of connective tissue which participates in formation of every organ.
Alun Wall, Tim Board
+9 more sources
Comparative Antimicrobial Effects of Rat Blood-derived Products and Adipose-derived Mesenchymal Stem Cell Conditioned Medium [PDF]
Background: The antimicrobial characteristics of biological products are fundamental in medicine due to their ability to treat microbial infections. This research aimed to assess and compare the antimicrobial properties of various platelet concentrates ...
Mohsen Sheykhhasan +3 more
doaj
This study was done to evaluate the effect of different quercetin levels on growth performance, immune responses, antioxidant status, serum biochemical factors, and high-temperature stress responses in common carp (Cyprinus carpio). A total number of 216
Kobra Armobin +7 more
doaj +1 more source
Allelic variation in TUSC1 gene: rs1462218557 is associated with male infertility and azoospermia
Background Male infertility is rapidly growing, and single nucleotide polymorphism (SNP) association studies are of critical importance. Tumor suppressor candidate 1 (TUSC1) gene is associated with azoospermia.
Zahra Vahidi Emami +2 more
doaj +1 more source
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro +7 more
doaj +1 more source
Stem cell therapy in renal diseases [PDF]
Objective: to evaluate the stem cell in treating renal diseases. To evaluate the effect of stem cells on renal cell apoptosis and necroptosis. Background: The use of stem cells is the hope for all patients with end-stage renal diseases.
Khalil Alhalfawy +4 more
doaj +1 more source

