Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence [PDF]
, 2017 Multicellular spheroids are an established system for three-dimensional cell culture. Spheroids are typically generated using hanging drop or non-adherent culture; however, an emerging technique is to use magnetic levitation.
Berry, Catherine C. +5 more
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Eph-Ephrin Signaling Mediates Cross-Talk Within the Bone Microenvironment
Frontiers in Cell and Developmental Biology, 2021 Skeletal integrity is maintained through the tightly regulated bone remodeling process that occurs continuously throughout postnatal life to replace old bone and to repair skeletal damage. This is maintained primarily through complex interactions between
Agnieszka Arthur +3 more
doaj +1 more source
Suicide-Gene Transfection of Tumor-tropic Placental Stem Cells employing Ultrasound-Responsive Nanoparticles [PDF]
Acta Biomaterialia. 83, 372-378 (2018), 2021 A Trojan-horse strategy for cancer therapy employing tumor-tropic mesenchymal stem cells transfected with a non-viral nanovector is here presented. In this sense, ultrasound-responsive mesoporous silica nanoparticles were coated with a polycation (using two different molecular weights), providing them with gene transfection capabilities that were ...
arxiv +1 more source
Comparative Antimicrobial Effects of Rat Blood-derived Products and Adipose-derived Mesenchymal Stem Cell Conditioned Medium [PDF]
Research in Molecular Medicine, 2023 Background: The antimicrobial characteristics of biological products are fundamental in medicine due to their ability to treat microbial infections. This research aimed to assess and compare the antimicrobial properties of various platelet concentrates ...
Mohsen Sheykhhasan +3 more
doaj
Aquaculture Nutrition, 2023 This study was done to evaluate the effect of different quercetin levels on growth performance, immune responses, antioxidant status, serum biochemical factors, and high-temperature stress responses in common carp (Cyprinus carpio). A total number of 216
Kobra Armobin +7 more
doaj +1 more source
Low-intensity pulsed ultrasound promotes mesenchymal stem cell transplantation-based articular cartilage regeneration via inhibiting the TNF signaling pathway [PDF]
Stem Cell Res Ther 14, 93 (2023), 2021 Background: Mesenchymal stem cell (MSC) transplantation therapy is highly investigated for the regenerative repair of cartilage defects. Low-intensity pulsed ultrasound (LIPUS) has the potential to promote chondrogenic differentiation of MSCs. However, its underlying mechanism remains unclear.
arxiv +1 more source
Allelic variation in TUSC1 gene: rs1462218557 is associated with male infertility and azoospermia
Egyptian Journal of Medical Human Genetics, 2023 Background Male infertility is rapidly growing, and single nucleotide polymorphism (SNP) association studies are of critical importance. Tumor suppressor candidate 1 (TUSC1) gene is associated with azoospermia.
Zahra Vahidi Emami +2 more
doaj +1 more source
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Scientific Reports, 2020 Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro +7 more
doaj +1 more source
Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]
PLoS ONE, 2013 Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova +2 more
doaj +1 more source
Stem Cell Research & Therapy, 2020 Background During development, excessive osteogenic differentiation of mesenchymal progenitor cells (MPC) within the cranial sutures can lead to premature suture fusion or craniosynostosis, leading to craniofacial and cognitive issues.
Clara Pribadi +5 more
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