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The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold ...
Mahshid Saleh   +4 more
doaj   +1 more source

Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

open access: yesInternational Journal of Molecular Sciences, 2017
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to their capacity for local engrafting and differentiating into multiple tissue types.
F. Vizoso   +4 more
semanticscholar   +1 more source

Mesenchymal Stem Cells as Therapeutics [PDF]

open access: yesAnnual Review of Biomedical Engineering, 2010
Mesenchymal stem cells (MSCs) are multipotent cells that are being clinically explored as a new therapeutic for treating a variety of immune-mediated diseases. First heralded as a regenerative therapy for skeletal tissue repair, MSCs have recently been shown to modulate endogenous tissue and immune cells.
Biju, Parekkadan, Jack M, Milwid
openaire   +2 more sources

Boosting the Biogenesis and Secretion of Mesenchymal Stem Cell-Derived Exosomes

open access: yesbioRxiv, 2020
A limitation to using exosomes to their fullest potential is their limited secretion from cells, a major bottleneck to efficient exosome production and application.
Jinli Wang   +3 more
semanticscholar   +1 more source

Isolation and Characterization of Feline Wharton’s Jelly-Derived Mesenchymal Stem Cells

open access: yesVeterinary Sciences, 2021
Wharton’s jelly is a well-known mesenchymal stem cell source in many species, including humans. However, there have been no reports confirming the presence of mesenchymal stem cells in Wharton’s jelly in cats.
Min-Soo Seo   +6 more
doaj   +1 more source

Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration

open access: yesCells, 2020
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication. With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the characteristics of producer cells, exosomes can be utilized as cell-free ...
D. Ha   +11 more
semanticscholar   +1 more source

Mesenchymal Stem Cell Migration and Tissue Repair

open access: yesCells, 2019
Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and differentiate into a variety of cell types, which play key roles in tissue healing and regenerative medicine.
Xiaorong Fu   +5 more
semanticscholar   +1 more source

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization

open access: yesAging, 2020
Osteoarthritis is a chronic degenerative disease that can lead to restricted activity or even disability. Bone marrow mesenchymal stem cells can repair cartilage damage and treat osteoarthritis via cell therapies or in-tissue engineering.
Jiyong Zhang   +3 more
semanticscholar   +1 more source

Mesenchymal Stem Cells in Cardiology [PDF]

open access: yes, 2016
Cardiovascular disease (CVD) accounts for more deaths globally than any other single disease. There are on average 1.5 million episodes of myocardial infarction (heart attack) each year in the United States alone with roughly one-third resulting in death.
Ian A, White   +3 more
openaire   +2 more sources

Sustained release of exosomes loaded into polydopamine-modified chitin conduits promotes peripheral nerve regeneration in rats

open access: yesNeural Regeneration Research, 2022
Exosomes derived from mesenchymal stem cells are of therapeutic interest because of their important role in intracellular communication and biological regulation.
Ci Li   +7 more
doaj   +1 more source

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