Results 61 to 70 of about 475,787 (198)

Alginate-encapsulated brain-derived neurotrophic factor–overexpressing mesenchymal stem cells are a promising drug delivery system for protection of auditory neurons

open access: yesJournal of Tissue Engineering, 2020
The cochlear implant outcome is possibly improved by brain-derived neurotrophic factor treatment protecting spiral ganglion neurons. Implantation of genetically modified mesenchymal stem cells may enable the required long-term brain-derived neurotrophic ...
Jana Schwieger   +6 more
doaj   +1 more source

Odontogenic MSC Heterogeneity: Challenges and Opportunities for Regenerative Medicine

open access: yesFrontiers in Physiology, 2022
Cellular heterogeneity refers to the genetic and phenotypic differences among cells, which reflect their various fate choices, including viability, proliferation, self-renewal probability, and differentiation into different lineages.
Yuan Chen   +6 more
doaj   +1 more source

A multicenter experience using adipose-derived mesenchymal stem cell therapy for cats with chronic, non-responsive gingivostomatitis. [PDF]

open access: yes, 2020
BackgroundThe ability of mesenchymal stem cells (MSCs) to modulate immune responses inspired a series of clinical trials addressing oral mucosal inflammation.
Arzi, Boaz   +12 more
core   +1 more source

Platelet lysate as a serum substitute for 2D static and 3D perfusion culture of stromal vascular fraction cells from human adipose tissue [PDF]

open access: yes, 2009
Fetal bovine serum (FBS) and fibroblast growth factor (FGF)-2 are key supplements for the culture of stromal vascular fraction (SVF) cells from adipose tissue, both for typical monolayer (2D) expansion and for streamlined generation of osteogenic ...
Alini, Mauro   +8 more
core   +1 more source

Effect of Platelet-rich Plasma and Mesenchymal Stem Cells as Two Biological Alternatives in Rotator Cuff Injury Treatment: A Mini-review

open access: yesResearch in Molecular Medicine, 2019
The rotator cuff injury is caused by significant damage by trauma or other factors and currently recognized as a prevalent orthopedic problem. Many clinical procedures have been proposed to reduce the complication of rotator cuff injury with varying ...
Mohsen Sheykhhasan   +4 more
doaj  

Induced pluripotent stem cell–derived mesenchymal stem cells enhance acellular nerve allografts to promote peripheral nerve regeneration by facilitating angiogenesis

open access: yesNeural Regeneration Research
Previous research has demonstrated the feasibility of repairing nerve defects through acellular allogeneic nerve grafting with bone marrow mesenchymal stem cells. However, adult tissue–derived mesenchymal stem cells encounter various obstacles, including
Fan-Qi Meng   +16 more
doaj   +1 more source

ADMINISTRATION OF BONE MARROW DERIVED MESENCHYMAL STEM CELLS MODULATE TLR EXPRESSION DURING LIVER REGENERATION

open access: yesTrakya University Journal of Natural Sciences, 2019
Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing stem cells to effectively ...
İhsan Gursel   +4 more
doaj   +1 more source

Comments on: “Mesenchymal stem cells transplantation for perianal fistulas: a systematic review and meta-analysis of clinical trials”

open access: yesStem Cell Research & Therapy, 2023
The meta-analysis by Wang et al. (Stem Cell Res Ther 14(1):103, 2023) aims to explore whether mesenchymal stem cells are effective for perianal fistulas.
Fang Cheng
doaj   +1 more source

Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy [PDF]

open access: yes, 2020
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, including neurological disorders ...
Capilla González, Vivian   +4 more
core   +1 more source

Role of miRNAs from mesenchymal stem cell–derived extracellular vesicles in neuroinflammation and behavioral impairments induced by chronic alcohol consumption in female mice

open access: yesNeural Regeneration Research
Mesenchymal stem cell–derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy; indeed, micro (mi)RNAs contained within mesenchymal stem cell–derived extracellular vesicles modulate target gene ...
Susana Mellado   +8 more
doaj   +1 more source

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