Results 71 to 80 of about 1,146,077 (364)
Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications.
Molecular Therapy, 2015 Mesenchymal stem (stromal) cells (MSCs) are multipotent cells with the ability to differentiate into several cell types, thus serving as a cell reservoir for regenerative medicine.
S. Rani, A. Ryan, M. Griffin, T. Ritter
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Introduce Characteristic, Types and Functional Mechanism of Adjuvants as a Biologic Complement [PDF]
Journal of Advanced Biomedical Sciences, 2019 The widespread use of effective vaccines against infectious diseases has been one of the most important public health progresses in the 21st century.
Tahereh Zarei Taher +5 more
doaj
Trakya University Journal of Natural Sciences, 2019 Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing stem cells to effectively ...
İhsan Gursel +4 more
doaj +1 more source
Journal of Tissue Engineering, 2020 The cochlear implant outcome is possibly improved by brain-derived neurotrophic factor treatment protecting spiral ganglion neurons. Implantation of genetically modified mesenchymal stem cells may enable the required long-term brain-derived neurotrophic ...
Jana Schwieger +6 more
doaj +1 more source
Use of mesenchymal stem cell therapy in COVID-19 related strokes
Neural Regeneration Research, 2023 Coronavirus disease 2019 (COVID-19) has affected a broad demographics, eliciting a more significant effect on specific groups such as males, African Americans, and Hispanic minorities.
Mahika Rawat +6 more
doaj +1 more source
Neural Regeneration Research, 2019 Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural plasticity and improve cognitive impairment. The purpose of this study was to investigate the effects of mesenchymal stem cell-derived exosomes on neurogenesis and ...
E. E. Reza-Zaldivar +8 more
semanticscholar +1 more source
Mesenchymal stem cells and their microenvironment
Frontiers in Bioscience, 2011 Mesenchymal stem cells (MSC) are multipotent stem cells that hold promise for an expanding list of therapeutic uses, not only due to their ability to differentiate into all connective tissues including bone, fat and cartilage, but additionally due to their trophic and anti-inflammatory effects which contribute to healing and tissue regeneration ...
Ingrid U, Schraufstatter +2 more
openaire +2 more sources
Mesenchymal stem cells: From stem cells to sarcomas [PDF]
Cell Biology International, 2016 AbstractMesenchymal stem cells (MSCs) have garnered vast interests in clinical settings, especially in regenerative medicine due to their unique properties—they are reliably isolated and expanded from various tissue sources; they are able to differentiate into mesodermal tissues such as bones, cartilages, adipose tissues, and muscles; and they have ...
Lye, Kwan Liang +3 more
openaire +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source