Results 41 to 50 of about 1,363,551 (403)

Mesenchymal stem cell-educated macrophages [PDF]

Transplantation Research, 2012
Mesenchymal stem cells (MSC) mediate their immunosuppressive effects via a variety of mechanisms. One of these mechanisms involves the induction of macrophages with immunomodulatory capacities. This effect of MSC may be exploited when MSC are used as a cell therapeutic product.
Elke Eggenhofer, Martin J Hoogduijn
openaire   +5 more sources

Comparison of Three Types of Mesenchymal Stem Cells (Bone Marrow, Adipose Tissue, and Umbilical Cord-Derived) as Potential Sources for Inner Ear Regeneration [PDF]

, 2017
In this review, we compared the potential of mesenchymal stem cells derived from bone marrow, adipose tissue and umbilical cord as suitable sources for regeneration of inner ear hair cells and auditory neurons.
Ameneh Mehri-Ghahfarrokhi, Masoud Saidijam, Masoud Saidijam, Mohammad-Reza Mahmoudian-sani, Mohammad-Saeid Jami, Morteza Hashemzadeh-Chaleshtori   +5 more
core   +2 more sources

Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail

Stem Cells International, 2019
Human mesenchymal stem cells (MSCs) are good candidates for brain cell replacement strategies and have already been used as adjuvant treatments in neurological disorders.
Lorena V. Cortés-Medina, Herminia Pasantes-Morales, Alejandro Aguilera-Castrejon, Arturo Picones, Cesar O. Lara-Figueroa, Enoch Luis, Juan Jose Montesinos, Victor A. Cortés-Morales, M. P. De la Rosa Ruiz, Erika Hernández-Estévez, Laura C. Bonifaz, Marco Antonio Alvarez-Perez, Gerardo Ramos-Mandujano   +12 more
doaj   +1 more source

Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages

Haematologica, 2010
Background Bone marrow mesenchymal stem cells support proliferation and differentiation of hematopoietic progenitor cells in vitro. Since these cells constitute a rare subset of bone marrow cells, mesenchymal stem cell preparations for clinical purposes ...
Alexandra Briquet, Sophie Dubois, Sandrine Bekaert, Marie Dolhet, Yves Beguin, André Gothot   +5 more
doaj   +1 more source

Mesenchymal stem cells and immunomodulation: current status and future prospects

Cell Death and Disease, 2016
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them an invaluable cell type for the repair of tissue/ organ damage caused by chronic inflammation or autoimmune disorders.
F. Gao, S. Chiu, Dal A. L. Motan, Z. Zhang, L. Chen, Hongda Ji, H. Tse, Qinf-Ling Fu, Q. Lian   +8 more
semanticscholar   +1 more source

Induced Stem Cells as a Novel Multiple Sclerosis Therapy. [PDF]

, 2016
Stem cell replacement is providing hope for many degenerative diseases that lack effective therapeutic methods including multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. Transplantation of neural stem cells or
Guan, Yang-Tai, Liu, Yan-Qun, Xie, Chong, Zhang, Guang-Xian   +3 more
core   +2 more sources

Mesenchymal stem cells and induced pluripotent stem cells as therapies for multiple sclerosis. [PDF]

, 2015
Multiple sclerosis (MS) is a chronic, autoimmune, inflammatory demyelinating disorder of the central nervous system that leads to permanent neurological deficits.
Biswas, Sangita, Deng, Wenbin, Qin, Xin, Xiao, Juan, Yang, Rongbing, Zhang, Min   +5 more
core   +3 more sources

Cinnamtannin B-1 Promotes Migration of Mesenchymal Stem Cells and Accelerates Wound Healing in Mice.

PLoS ONE, 2015
Substances that enhance the migration of mesenchymal stem cells to damaged sites have the potential to improve the effectiveness of tissue repair. We previously found that ethanol extracts of Mallotus philippinensis bark promoted migration of mesenchymal
Kosuke Fujita, Katsunori Kuge, Noriyasu Ozawa, Shunya Sahara, Kaori Zaiki, Koichi Nakaoji, Kazuhiko Hamada, Yukiko Takenaka, Takao Tanahashi, Katsuto Tamai, Yasufumi Kaneda, Akito Maeda   +11 more
doaj   +1 more source

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

Cell Death and Differentiation, 2016
Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered in bone marrow, are multipotent cells capable of differentiating into mature cells of several mesenchymal tissues, such as fat and bone.
Q. Chen, P. Shou, C. Zheng, M. Jiang, G. Cao, Q. Yang, J. Cao, N. Xie, T. Velletri, X. Zhang, C. Xu, L. Zhang, H. Yang, J. Hou, Y. Wang, Y. Shi   +15 more
semanticscholar   +1 more source

Ablation of Proliferating Marrow with 5‐Fluorouracil Allows Partial Purification of Mesenchymal Stem Cells [PDF]

, 2006
The ability to identify and maintain mesenchymal stem cells in vitro is a prerequisite for the ex vivo expansion of cells capable of effecting mesenchymal tissue regeneration. The aim of this investigation was to develop an assay to enrich and ultimately
Krebsbach, Paul H., Song, Junhui, Taichman, Russell S., Wang, Zhuo   +3 more
core   +1 more source