Results 51 to 60 of about 90,342 (257)
Stem Cell Research & Therapy, 2021 Background Chemotherapy is an effective anti-tumor treatment. Mesenchymal stem cells (MSCs), exerting therapy effect on injured tissues during chemotherapy, may be damaged in the process.
Huifang Li +12 more
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
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Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
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Two MSCs: Marrow stromal cells and mesenchymal stem cells
Inflammation and Regeneration, 2007 Marrow stromal cells (MSC1) are able to generate a series of terminally-differentiated cells in vitro. Most experiments are performed with heterogeneous stromal cells obtained by adherence to plastic culture dishes. Since bone marrow-derived stromal cells are purified to a homogeneous population meeting the criteria for non-hematopoietic stem cells ...
Umezawa, Akihiro, Toyoda, Masashi
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Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials
Stem Cell Research & Therapy, 2023 AbstractMesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their robust immunomodulatory and regenerative properties. Their paracrine activity is one of the most important features that contribute to their efficacy. Recently, it has been demonstrated that the production of various factors via extracellular vesicles ...
Ahmed Lotfy +2 more
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Journal of Animal Reproduction and BiotechnologyBackground: Pluripotent stem cells (PSCs) are capable of differencing into various cell types in the body, providing them valuable for therapy of degenerative diseases.
Yeon-Ji Lee +6 more
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Antitumor Effect of Mesenchymal Stem Cells from Murine in Breast Cancer in Female Rats [PDF]
Benha Veterinary Medical Journal, 2018 The aim of this study was to evaluate the effect of mesenchymal stem cells as a treatment against breast cancer via modulation TGF-β. Mesenchymal stem cells (MSCs) are recruited to the stroma of cancers.
Omayma A.R. AbouZaid +3 more
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Advanced Engineering Materials, EarlyView.In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
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Stem Cells Translational Medicine, 2016 Summary Human endometrium is a highly regenerative tissue, undergoing more than 400 cycles of proliferation, differentiation, and shedding during a woman's reproductive life.
Saeedeh Darzi +3 more
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Biomedicines, 2022 The potential role of mesenchymal stem cells (MSCs) in the treatment of metastatic cancers, including breast cancer, has been investigated for many years leading to encouraging results. The role of fat grafting and the related adipose-derived mesenchymal
Pietro Gentile
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