Results 201 to 210 of about 143,813 (266)

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

Safety of intravascular administration of umbilical-cord-derived mesenchymal stromal cells: an updated systematic review and meta-analysis. [PDF]

Stem Cells Transl Med
Hum C, Poliwoda J, Lalu M, Stewart DJ, Mei SHJ, Walley KR, Marshall J, Mendelson AA, Fergusson DA, English S, Winston BW, Granton J, Dos Santos CC, Champagne J, McIntyre L.   +14 more
europepmc   +1 more source

Cellular Allies Against Glioblastoma: Therapeutic Potential of Macrophages and Mesenchymal Stromal Cells. [PDF]

Pharmaceutics
Cesca BA, Pellicer San Martin K, Ibarra LE.   +2 more
europepmc   +1 more source

Transcriptome‐Based Classification of Resected Pancreatic Ductal Adenocarcinoma Enhances Prognostic Modelling Accuracy of Overall Survival Following Adjuvant Treatment

International Journal of Cancer, EarlyView.
Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen, Vincent R. Lanting, Paul Manoukian, Marc G. Besselink, Geert Kazemier, Ignace H. J. T. de Hingh, Mike S. L. Liem, Casper H. J. van Eijck, Erwin van der Harst, Vincent E. de Meijer, Ronald M. van Dam, Martijn W. J. Stommel, Jan Koster, Michael W. T. Tanck, Arantza Fariña Sarasqueta, Joanne Verheij, Frederike Dijk, Johanna W. Wilmink, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven, for the Dutch Pancreatic Cancer Group   +20 more
wiley   +1 more source

Influence of Stress-Induced Senescence on the Secretome of Primary Mesenchymal Stromal Cells. [PDF]

Biomolecules
Kashirina D, Matveeva D, Ezdakova M, Brzhozovskiy A, Kononikhin A, Pastushkova L, Larina I, Nikolaev E, Buravkova L, Ratushnyy A.   +9 more
europepmc   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik, Candan Eker, Berivan Guzelbag, Ercan Bastu, Tuba Gunel   +4 more
wiley   +1 more source

Mesenchymal Stromal Cells Improve Islet β-Cell Functional Survival: Analysis of Extracellular Vesicle-Trafficked Proteins and miRNAs. [PDF]

Cells
Hong TW, Sullivan R, Arora R, Lonsane A, Lyu Z, Caxaria S, Huang TC, Daniels Gatward LF, Burgoyne T, King AJF, Persaud SJ, Jones PM.   +11 more
europepmc   +1 more source

Human induced pluripotent stem cell-derived mesenchymal stromal cells regenerate diabetic ischemic muscle. [PDF]

Bioeng Transl Med
Basu R, Madison MK, Sualeh A, Clark TS, Stashevsky J, Aridi HD, Zhang N, Anekal S, Murphy MP, Miller SJ, Gil CH.   +10 more
europepmc   +1 more source

Post‐Translational Modifications of Key Proteins in Hematologic Malignancies: Carcinogenic Mechanisms, Biomarker Potential, and New Therapeutic Strategies

iLABMED, EarlyView.
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han, Chaowei Zhang, Weiyi Yao, Qing Hong, Xinyu Tang, Yanan Zhu, Na Chen   +6 more
wiley   +1 more source

Engineered Mesenchymal Stromal Cells in Oncology: Navigating Between Therapeutic Delivery and Tumor Promotion. [PDF]

Genes (Basel)
Warzycha M, Oleksiuk A, Suska O, Kolanowski TJ, Rozwadowska N.   +4 more
europepmc   +1 more source