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Finessing the manufacture of mesenchymal stromal cells

Cytotherapy, 2014
Mesenchymal stromal cells (MSCs) are an appealing cellular therapy, with early-phase clinical studies underway as therapies for acute graft-versus-host disease, inflammatory bowel disease, diabetes, wound repair and other diseases. The relative ease with which these cells can be expanded makes them especially appealing.
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Cryopreservation and Revival of Mesenchymal Stromal Cells

2011
Over the past few years, the pace of preclinical stem cell research is astonishing and adult stem cells have become the subject of intense research. Due to the presence of promising supporting preclinical data, human clinical trials for stem cell regenerative treatment of various diseases have been initiated.
Haack-Sørensen, Mandana, Kastrup, Jens
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Immunomodulation by Multipotent Mesenchymal Stromal Cells

Transplantation, 2007
Multipotent mesenchymal stromal cells (MSC) are currently under intense investigation to determine their role in cellular therapy. They are a rare subset of cells, but are easy to isolate and possess an extensive proliferative potential. MSC differentiate into cell types of mesenchymal and nonmesenchymal lineages, providing a promising tool for tissue ...
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Mesenchymal stromal cells and rheumatic disorders

Immunology Letters, 2015
Mesenchymal stromal cells (MSC), often incorrectly called stem cells, have been the intense focus of in vitro studies and animal models of rheumatic and other diseases over more than a decade. Despite multiple plausible mechanisms of action and a plethora of positive in vivo animal studies, few randomised controlled clinical trials have demonstrated ...
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Immunomodulatory Properties of Mesenchymal Stromal Cells: An Update

Frontiers in Cell and Developmental Biology, 2021
Manja Wobus   +2 more
exaly  

CD39 Expression in Mesenchymal Stromal Cells

Journal of Immunotherapy, 2011
Felipe, Saldanha-Araujo   +1 more
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Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

Cell Stem Cell, 2018
Jacques Galipeau, Luc Sensebé
exaly  

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