Results 121 to 130 of about 94,714 (283)

Skeletal Dysplasia During the Bronze Age in Northeast Thailand (3000–2500 BP)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This study examines a case of skeletal dysplasia in an adult male (B290) from the Bronze Age at the site of Ban Non Wat, Northeast Thailand. Skeletal dysplasia, a group of genetic disorders affecting bone and cartilage growth, presents diagnostic challenges due to overlapping clinical features.
Nuttheera Kaoboriboon, Nancy Tayles, Sarah Agatha Villaluz, Pratiwi Yuwono, Kate Domett, Melandri Vlok   +5 more
wiley   +1 more source

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source

Minimally invasive sacroiliac joint fusion: Primary endpoint results from the prospective, multicenter STACI study

PM&R, EarlyView.
Abstract Background Chronic sacroiliac joint (SIJ) pain is highly debilitating. Minimally invasive SIJ fusion has become a commonly performed surgical treatment for SIJ pain, with level I evidence showing clinically significant improvements in pain, function, and quality of life and a low adverse event rate.
Jacqueline Weisbein, Timothy Davis, Douglas Beall, Jack Smith, Caroline Harstroem, Daniel Kloster, Morteza Rabii, Robyn Capobianco, Ramana Naidu, Michael Harned, Christopher Mallard, the STACI investigators   +11 more
wiley   +1 more source

Tissue-engineered cartilage regeneration based on human induced pluripotent stem cells

Kouqiang hemian waike zazhi
[Objective:] To establish a stable and efficient culture approach for guiding human induced pluripotent stem cells (hiPSCs) differentiation towards chondrogenic mesodermal lineage, and preliminarily explore the possibility of hiPSCs-derived cartilaginous
LI Yangyang, ZHANG Maolin, ZOU Duohong, ZHANG Zhiyuan   +3 more
doaj   +1 more source

Competence, specification and induction of Pax-3 in the trigeminal placode [PDF]

, 1999
Placodes are discrete regions of thickened ectoderm that contribute extensively to the peripheral nervous system in the vertebrate head. The paired-domain transcription factor Pax-3 is an early molecular marker for the avian ophthalmic trigeminal (opV ...
Baker, Clare V. H., Bronner-Fraser, Marianne, Marcelle, Christophe, Stark, Michael R.   +3 more
core  

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source

Titanium Detected in Liver, Kidney, Spleen, and Intestine Is Not Related to Dose, Time, or Route of Exposure to Titanium Dioxide: A Systematic Review

Environmental Toxicology, EarlyView.
ABSTRACT Titanium dioxide (TiO2), used as a food additive (labeled E171 in Europe), was withdrawn from the European market in 2022. The E171 toxicity mechanism involves its uptake, oxidative stress, DNA damage, and inflammation. It has been hypothesized that the TiO2 accumulation nanoparticles (NPs) or E171 triggers tissue damage, and some studies have
Carmen Ximena Martínez‐Escutia, Estefany I. Medina‐Reyes, Eduardo Delgado‐Armenta, Yolanda I. Chirino   +3 more
wiley   +1 more source

Induced Pluripotent Stem Cells as a Tool to Decipher the Normal and Abnormal Development of the Esophagus and Trachea from Normal Morphogenesis to Esophageal Atresia, Tracheomalacia, and Laryngo–Tracheal Clefts

Cells
The development of the esophagus and trachea following the septation of the anterior foregut is a highly regulated process involving bidirectional communication between the endoderm and mesoderm.
Yuxuan Zhang, Anu David, Alireza Nemati, Christophe Faure   +3 more
doaj   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

extraembryonic mesoderm

Citation: 'extraembryonic mesoderm' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10701 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source