Results 91 to 100 of about 14,708 (190)
In Vivo Regulation of the μ Opioid Receptor: Role of the Endogenous Opioid Agents
Molecular Medicine, 2013 It is well known that genotypic differences can account for the subject-specific responses to opiate administration. In this regard, the basal activity of the endogenous system (either at the receptor or ligand level) can modulate the effects of ...
Veronica Gonzalez-Nunez +3 more
doaj +1 more source
Chemistry &Biodiversity, Volume 22, Issue 11, November 2025.ABSTRACT Maize is an important crop worldwide with approximately 1200 million tons consumed and a market size worth $143 billion. Environmental stress influence production of crops and mitigating these ensures optimum production. Dicarboxylic acids are known as emulsifying agents that mitigate various stresses in plants.
Mhlonipheni Msomi +3 more
wiley +1 more source
Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
, 1995 Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core +1 more source
μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks
Annals of Neurology, Volume 98, Issue 4, Page 777-787, October 2025.Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim +6 more
wiley +1 more source
Study of Immunotherapy with Endogenous Opiod (Met-Enkephalin) Activated TILs in Fibrosarcoma Induced Balb/C Mice [PDF]
Cell Journal, 2010 Objective: In this study the effects of met-enkephalin on tumor infiltrating lymphocytesfor cancer treatment in fibrosarcoma bearing mice was evaluated.Materials and Methods: Initially, to obtain the most effective dose and treating time forthe ...
Abbas Ali Amini +6 more
doaj
Simulated Annealing with Tsallis Weights - A Numerical Comparison
, 1997 We discuss the use of Tsallis generalized mechanics in simulated annealing algorithms. For a small peptide it is shown that older implementations are not more effective than regular simulated annealing in finding ground state configurations. We propose a
Andricioaei +15 more
core +1 more source
Generalized-ensemble simulations of spin systems and protein systems
, 2001 In complex systems such as spin systems and protein systems, conventional simulations in the canonical ensemble will get trapped in states of energy local minima.
Ayori Mitsutake +32 more
core +1 more source
Met-enkephalins in patients with inflammatory bowel diseases
Advances in Medical Sciences, 2011 Opioid peptides provide a link between the neuroendocrine and immune systems. They modify the inflammatory process through their effect on the synthesis and secretion of cytokines and on the proliferation of leukocytes to the inflammatory lesion. The evaluation analyzed changes in free met-enkephalin concentration values in the serum and colon mucosal ...
Owczarek, Danuta +6 more
openaire +3 more sources
Neutrophil-Mediated Endogenous Analgesia Contributes to Sex Differences in Oral Cancer Pain
Frontiers in Integrative Neuroscience, 2018 The incidence of oral cancer in the United States is increasing, especially in young people and women. Patients with oral cancer report severe functional pain.
Nicole N. Scheff +8 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2014 Opioid receptors are expressed in the vestibular endorgans (afferent neurons and hair cells) and are activated by the efferent system, which modulates the discharge of action potentials in the vestibular afferent neurons (VANs).
Emmanuel eSeseña +2 more
doaj +1 more source