Results 21 to 30 of about 14,708 (190)
Rugged Metropolis Sampling with Simultaneous Updating of Two Dynamical Variables [PDF]
, 2005 The Rugged Metropolis (RM) algorithm is a biased updating scheme, which aims at directly hitting the most likely configurations in a rugged free energy landscape. Details of the one-variable (RM$_1$) implementation of this algorithm are presented.
B. A. Berg +7 more
core +1 more source
Influence of Mutations of Conserved Arginines on Neuropeptide Binding in the DPP III Active Site
Molecules, 2023 Dipeptidyl peptidase III (DPP III), a zinc exopeptidase, is involved in the final steps of intercellular protein degradation and has a marked affinity for opioid peptides such as enkephalins and endomorphins.
Antonija Tomić +2 more
doaj +1 more source
Biased Metropolis Sampling for Rugged Free Energy Landscapes [PDF]
, 2003 Metropolis simulations of all-atom models of peptides (i.e. small proteins) are considered. Inspired by the funnel picture of Bryngelson and Wolyness, a transformation of the updating probabilities of the dihedral angles is defined, which uses ...
Berg, Bernd A.
core +3 more sources
Journal of Health Sciences, 2015 Introduction: The met-enkephalin (1-5 Adrenorphin) and tridecactide (alpha-corticotropin 1-13) combination is used in the multiple sclerosis (MS) immuno-modulatory treatment.
Maida Rakanovic-Todic +5 more
doaj +1 more source
High resolution NMR study of T1 magnetic relaxation dispersion. IV. Proton relaxation in amino acids and Met-enkephalin pentapeptide [PDF]
, 2014 Nuclear Magnetic Relaxation Dispersion (NMRD) of protons was studied in the pentapeptide Met-enkephalin and the amino acids, which constitute it. Experiments were run by using high-resolution Nuclear Magnetic Resonance (NMR) in combination with fast ...
Ivanov, Konstantin L. +3 more
core +1 more source
Frontiers in PhysiologyIntroductionMet-enkephalin is a neuropeptide whose release into the circulation is enhanced by stress. There have been no studies on the effects of peripherally administered Met-enkephalin in chickens.MethodsThe effects of peripheral administration of ...
Krystyna Pierzchała-Koziec +2 more
doaj +1 more source
Annals of Hepatology, 2008 Endogenous opioids participate in growth regulation. Liver regeneration relates to growth. Thus, we explored the expression of methionine enkephalin and of the delta opioid receptor 1 immunoreactivities with a polyclonal rabbit antibody in deparaffinized
Vijaya D. Boyella +2 more
doaj +1 more source
Effective Sampling in the Configurational Space by the Multicanonical-Multioverlap Algorithm
, 2006 We propose a new generalized-ensemble algorithm, which we refer to as the multicanonical-multioverlap algorithm. By utilizing a non-Boltzmann weight factor, this method realizes a random walk in the multi-dimensional, energy-overlap space and explores ...
B. A. Berg +5 more
core +1 more source
Perspectives on Endogenous Opioids in Birds
Frontiers in Physiology, 2018 The present review summarizes the state of knowledge of endogenous opioids in birds. Endogenous opioid peptides acts in a neuromodulatory, hormonal and paracrine manner to mediate analgesic and other physiological functions.
Colin G. Scanes +1 more
doaj +1 more source
Nuclear‐Magnetic‐Resonance Study on Met‐enkephalin and Met‐enkephalin [PDF]
European Journal of Biochemistry, 1979 The 270‐MHz 1H and 68‐MHz 13C nuclear magnetic resonance spectra of Met‐enkephalin (Tyr‐Gly‐Gly‐Phe‐Met) and Met‐enkephalinamide are analyzed in a variety of solvents. For the dipolar form of Met‐enkephalin in (C2H3)2SO solution, significant concentration dependences are found of C‐α proton chemical shifts, indicating an aromatic ring‐current effect in
T, Higashijima +3 more
openaire +2 more sources