Results 21 to 30 of about 1,366,906 (203)
Opioid-like peptides and ghrelin mitigation of bariatric results depends on obesity level
Endokrynologia Polska, 2020 INTRODUCTION: Bariatric surgery, as the only effective treatment of obesity, has strong effects on the metabolism, and nervous and endocrine systems. Thus, based on the different opinions about the efficaciousness of morbid obesity treatments, the aim of
Michał Dyaczyński +6 more
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Frontiers in Physiology, 2023 The present review considers the putative hormonal opioid peptides in birds. In birds and all other vertebrates, there are four opioid related genes encoding a series of peptides.
Krystyna Pierzchała-Koziec +1 more
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The folding funnel landscape for the peptide met-enkephalin [PDF]
Proteins: Structure, Function, and Genetics, 1999 We study the free energy landscape of the small peptide Met-enkephalin. Our data were obtained from a generalized-ensemble Monte Carlo simulation taking the interactions among all atoms into account. We show that the free energy landscape resembles that of a funnel, indicating that this peptide is a good folder.
Hansmann, U. H. E. +2 more
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Actions of D-Ala2-D-Leu5-enkephalin and dynorphin A (1–17) on neocortical neurons in vitro [PDF]
, 1984 Intracellular recordings were made from neocortical neurons in vitro. Application of D-Ala2-D-Leu5-enkephalin (DADL) by different methods produced a decrease in EPSP amplitude and in the amplitude of L-glutamate-induced depolarizations without changes in
Zieglgänsberger, Walter, Sutor, Bernd
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Folia Histochemica et Cytobiologica, 2021 INTRODUCTION: A recent study has shown a close neuroanatomical relationship between the enkephalinergic (methionine-enkephalin) and tachykininergic (substance P) systems in the alpaca diencephalon.
Pablo Sánchez +5 more
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Frontiers in Medicine, 2021 Background: Chronic pruritus affects up to 70% of patients with immune-mediated hepatobiliary disorders. Antagonists of the μ-opioid receptor (MOR) and agonists of the κ-opioid receptor (KOR) are used to treat hepatic itch, albeit with limited success ...
Miriam M. Düll +7 more
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Journal of Health Sciences, 2015 Introduction: The met-enkephalin (1-5 Adrenorphin) and tridecactide (alpha-corticotropin 1-13) combination is used in the multiple sclerosis (MS) immuno-modulatory treatment.
Maida Rakanovic-Todic +5 more
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Influence of Mutations of Conserved Arginines on Neuropeptide Binding in the DPP III Active Site
Molecules, 2023 Dipeptidyl peptidase III (DPP III), a zinc exopeptidase, is involved in the final steps of intercellular protein degradation and has a marked affinity for opioid peptides such as enkephalins and endomorphins.
Antonija Tomić +2 more
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Nuclear‐Magnetic‐Resonance Study on Met‐enkephalin and Met‐enkephalin [PDF]
European Journal of Biochemistry, 1979 The 270‐MHz 1H and 68‐MHz 13C nuclear magnetic resonance spectra of Met‐enkephalin (Tyr‐Gly‐Gly‐Phe‐Met) and Met‐enkephalinamide are analyzed in a variety of solvents. For the dipolar form of Met‐enkephalin in (C2H3)2SO solution, significant concentration dependences are found of C‐α proton chemical shifts, indicating an aromatic ring‐current effect in
T, Higashijima +3 more
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Perspectives on Endogenous Opioids in Birds
Frontiers in Physiology, 2018 The present review summarizes the state of knowledge of endogenous opioids in birds. Endogenous opioid peptides acts in a neuromodulatory, hormonal and paracrine manner to mediate analgesic and other physiological functions.
Colin G. Scanes +1 more
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