Results 21 to 30 of about 10,961 (170)
Frontiers in Medicine, 2021 Background: Chronic pruritus affects up to 70% of patients with immune-mediated hepatobiliary disorders. Antagonists of the μ-opioid receptor (MOR) and agonists of the κ-opioid receptor (KOR) are used to treat hepatic itch, albeit with limited success ...
Miriam M. Düll +7 more
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Immunohistochemical studies on the gastrointestinal tract using antisera to Met-enkephalin and Met-enkephalin Arg6Phe7. [PDF]
Journal of Histochemistry & Cytochemistry, 1983 Antisera specific for the C-terminus of Met-enkephalin and two of its variants isolated from adrenal medulla and brain, namely Met-enk Arg6 and Met-enk Arg6Phe7, have been used in immunohistochemical studies of the gastrointestinal tract in rat, mouse and guinea pig.
A J, Bu'Lock, C, Vaillant, G J, Dockray
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Journal of Health Sciences, 2015 Introduction: The met-enkephalin (1-5 Adrenorphin) and tridecactide (alpha-corticotropin 1-13) combination is used in the multiple sclerosis (MS) immuno-modulatory treatment.
Maida Rakanovic-Todic +5 more
doaj +1 more source
Influence of Mutations of Conserved Arginines on Neuropeptide Binding in the DPP III Active Site
Molecules, 2023 Dipeptidyl peptidase III (DPP III), a zinc exopeptidase, is involved in the final steps of intercellular protein degradation and has a marked affinity for opioid peptides such as enkephalins and endomorphins.
Antonija Tomić +2 more
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Probing the Influence of Sulfur-Aromatic Interactions on the Electronic Structure of Gas-Phase Peptides. [PDF]
ChemistryJust as fingerprints reveal identity, spectroscopic fingerprints reveal molecular secrets. In this article, we show parts of the unique fingerprint of the sulfur–aromatic interaction. By measuring how this force alters the electronic structure of gas‐phase peptides, we provide a fundamental understanding of interactions that give insights into the ...
Pille L +12 more
europepmc +2 more sources
Nuclear‐Magnetic‐Resonance Study on Met‐enkephalin and Met‐enkephalin [PDF]
European Journal of Biochemistry, 1979 The 270‐MHz 1H and 68‐MHz 13C nuclear magnetic resonance spectra of Met‐enkephalin (Tyr‐Gly‐Gly‐Phe‐Met) and Met‐enkephalinamide are analyzed in a variety of solvents. For the dipolar form of Met‐enkephalin in (C2H3)2SO solution, significant concentration dependences are found of C‐α proton chemical shifts, indicating an aromatic ring‐current effect in
T, Higashijima +3 more
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Annals of Hepatology, 2008 Endogenous opioids participate in growth regulation. Liver regeneration relates to growth. Thus, we explored the expression of methionine enkephalin and of the delta opioid receptor 1 immunoreactivities with a polyclonal rabbit antibody in deparaffinized
Vijaya D. Boyella +2 more
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Perspectives on Endogenous Opioids in Birds
Frontiers in Physiology, 2018 The present review summarizes the state of knowledge of endogenous opioids in birds. Endogenous opioid peptides acts in a neuromodulatory, hormonal and paracrine manner to mediate analgesic and other physiological functions.
Colin G. Scanes +1 more
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Parasites & Vectors, 2015 Background In vertebrates, the presence of enteric worms can induce structural changes to the alimentary canal impacting on the neuroendocrine system, altering the proper functioning of the gastrointestinal tract and affecting the occurrence and relative
Giampaolo Bosi +3 more
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Folia Histochemica et Cytobiologica, 2020 INTRODUCTION: In the alpaca diencephalon, the distribution of immunoreactive cell bodies and fibers containing methionine-enkephalin (MET) or substance P (SP) has been studied. MATERIAL AND METHODS: The immunohistochemical study was performed by standard
Pablo Sánchez +4 more
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