Results 71 to 80 of about 14,708 (190)

Progress in Research on Alleviating the Symptoms Associated With Advanced Cancer Using Traditional Chinese Medicine

Pain Research and Management, Volume 2026, Issue 1, 2026.
Advanced cancer continues to pose a substantial global challenge, with complex symptom burdens and limited therapeutic options. Traditional Chinese Medicine (TCM), grounded in holistic theory and the principles of syndrome differentiation, employs interventions such as herbal medicine, acupuncture, moxibustion, and acupoint‐based therapies to address ...
Chunmeng Jiao, Ting Zhang, Yachen Yang, Ruofan Zhang, Wenbo Liu, Yanqing Wang, Lei Huang   +6 more
wiley   +1 more source

Effects of loperamide on the human hypothalamo-pituitary-adrenal axis in vivo and in vitro. [PDF]

, 1992
Loperamide, an opiate agonist of high specificity for p-receptors, was recently reported to suppress ACTH and cortisol levels in normal subjects, but not in patients with proven ACTH-dependent Cushing’s disease. However, there is little information on
Auernhammer, Christoph J., Lange, M., Müller, O.A., Pfeiffer, M., Stalla, G.K.   +4 more
core   +1 more source

Comprehensive Analysis of Sinomenii caulis and Menispermi rhizoma Based on Ultra‐High Performance Liquid Chromatography and Ultra‐High Performance Liquid Chromatography‐Quadrupole Time‐of‐Flight‐Mass Spectrometry

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT Sinomenii caulis (SC) and Menispermi rhizoma (MR) are Chinese herbal medicines from the same family and are often confused. To achieve identification of SC and MR, the paper used the differential chemical components and the combination characteristics of chemical components to carry out a comprehensive analysis.
Ye Tao, Xinyue Zhang, Wen Li, Zhe Wu, Shuchen Duan, Lizhi Wan, Xiangri Li, Yazhong Zhang, Xianlong Cheng, Feng Wei   +9 more
wiley   +1 more source

Peptide chirality and opioid receptor modulation: Hepatoprotective effect of d-Met-enkephalin in acetaminophen-induced liver injury

Acta Pharmaceutica
l-Met-enkephalin is a neuropeptide known to exert protective effects in various experimental models of autoimmune and inflammatory diseases. These effects are mediated through opioid receptors and can be abolished by the opioid receptor antagonist ...
Turčić Petra, Martinić Roko, Štambuk Nikola, Weitner Tin, Momčilović Mirna, Boban-Blagaić Alenka, Kos Marina, Stojković Ranko   +7 more
doaj   +1 more source

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

Frontiers in Cellular Neuroscience, 2015
The endogenous opioid peptides dynorphins and enkephalins may be involved in brain-area specific synaptic adaptations relevant for different stages of an addiction cycle.
Daniil eSarkisyan, Muhammad Z. Hussain, Hiroyuki eWatanabe, Olga eKononenko, Olga eKononenko, Igor eBazov, Xing Wu eZhou, Olga eYamskova, Oleg eKrishtal, Victor M. Karpyak, Tatiana eYakovleva, Georgy eBakalkin   +11 more
doaj   +1 more source

Unfolding Hidden Barriers by Active Enhanced Sampling

, 2017
Collective variable (CV) or order parameter based enhanced sampling algorithms have achieved great success due to their ability to efficiently explore the rough potential energy landscapes of complex systems.
Chen, Ming, Zhang, Jing
core   +1 more source

Adoptive transfer of M2 macrophages reduces neuropathic pain via opioid peptides [PDF]

, 2016
Background During the inflammation which occurs following nerve damage, macrophages are recruited to the site of injury. Phenotypic diversity is a hallmark of the macrophage lineage and includes pro-inflammatory M1 and anti- inflammatory M2 populations ...
Batra, Arvind, Celik, Melih O., Keye, Jacqueline, Labuz, Dominika, Machelska, Halina, Pannell, Maria, Siegmund, Britta   +6 more
core   +2 more sources

High Resolution Postmortem MRI Discovers Developing Structural Connectivity in the Human Ascending Arousal Network

Human Brain Mapping, Volume 46, Issue 17, 01 December 2025.
We used high‐resolution ex vivo diffusion MRI and graph theory to analyze ascending arousal network development in fetal to adult brains, revealing increasing rostral integration postnatally and identifying the dorsal raphe nucleus and ventral tegmental area as persistent connectivity hubs from fetal stages through adulthood.
Roxane Licandro, Mark Olchanyi, Luiz F. Ferraz da Silva, Andre van der Kouwe, Camilo Jaimes, Nathan X. Ngo, William Kelley, Rebecca Folkerth, Robin L. Haynes, Brian L. Edlow, Hannah C. Kinney, Lilla Zöllei   +11 more
wiley   +1 more source

Replica-exchange multicanonical algorithm and multicanonical replica-exchange method for simulating systems with rough energy landscape

, 2000
We propose two efficient algorithms for configurational sampling of systems with rough energy landscape. The first one is a new method for the determination of the multicanonical weight factor.
Bartels, Berg, Berg, Cornell, Evans, Ferrenberg, Ferrenberg, Hansmann, Hansmann, Hansmann, Hansmann, Hansmann, Hoover, Hukushima, Hukushima, Kitao, Kumar, Kumar, Mitsutake, Morikami, Nakajima, Smith, Sugita, Sugita, Swendsen, Tesi, Yamamoto, Yan, Yuji Sugita, Yuko Okamoto   +29 more
core   +1 more source

Parallel Tempering: Theory, Applications, and New Perspectives [PDF]

, 2005
We review the history of the parallel tempering simulation method. From its origins in data analysis, the parallel tempering method has become a standard workhorse of physiochemical simulations.
Alexander-Katz, Auer, Banaszak, Beauvais, Bedrov, Bertrand, Bogarad, Brunger, Bunker, Calco, Calvo, Cecchini, Chen, Chen, Chuang, Ciobanu, Coluzza, David J. Earl, DeWitte, Dova, Dozastakis, Dugourd, Earl, Ekdawi-Sever, Falcioni, Falcioni, Falcioni, Faller, Fasnacht, Favre-Nicolin, Feig, Fenwick, Frenkel, Fukunishi, Garcia, Garcia, Garcia-Cuesta, Gnanakaran, Habeck, Haliloglu, Hansmann, Houdayer, Im, Im, Ishikawa, Jang, Jas, Katzgraber, Katzgraber, Katzgraber, Katzgraber, Kihara, Kofke, Kofke, Kofke, Kokubo, Kokubo, Kone, Kozumi, Lopez, Manousiouthakis, Mastny, Merlitz, Michael W. Deem, Mitsutake, Mitsutake, Murata, Nguyen, Nymeyer, Okamoto, Ortiz, Pagan, Penna, Rabenstein, Rathore, Rathore, Rathore, Rathore, Rathore, Sanbonmatsu, Sanbonmatsu, Schug, Sengupta, Shin, Sugita, Sugita, Sujita, Swendsen, Tsallis, Vlugt, Vreede, Wang, Whitfield, Wu, Yan, Yan, Yan, Yang, Zavalij, Zhou, Zhou, Zhou, Zhou, Zhou   +103 more
core   +1 more source