Results 61 to 70 of about 1,153,004 (118)

Genotypic‐Phenotypic Correlations in Non‐HbE β‐Thalassemia Intermedia: A Geographic Systematic Review

Molecular Genetics &Genomic Medicine, Volume 14, Issue 11, November 2026.
β‐Thalassemia intermedia exhibits distinct region‐specific molecular patterns shaped by three interacting genetic axes: β‐globin mutation severity, HbF‐inducing modifiers, and α‐globin gene dosage. Mediterranean populations are predominantly mutation‐driven, Middle Eastern populations rely on HbF compensation, and Asian populations are governed by ...
Kavindya Fernando, Shiromi Perera, Anuja Premawardhena   +2 more
wiley   +1 more source

Using transcriptome profiling to characterize QTL regions on chicken chromosome 5 [PDF]

, 2009
Background Although many QTL for various traits have been mapped in livestock, location confidence intervals remain wide that makes difficult the identification of causative mutations. The aim of this study was to test the contribution of microarray data
Désert Colette, Behnam Abasht, Sophie Leroux, Demeure Olivier, Pitel, Frédérique, Guillaume Le Mignon, Desert, C., Le Mignon, Guillaume, Le Mignon Guillaume, Pitel, F., Pascale Le Roy, Gregory Guernec, Douaire Madeleine, Lagarrigue Sandrine, Leroux, S., Désert, Colette, Lagarrigue, S., Demeure, O., Abasht, B., Colette Désert, Frédérique Pitel, Leroux, Sophie, Le Roy, P., Sandrine Lagarrigue, Le Roy, Pascale, Lagarrigue, Sandrine, Olivier Demeure, Le Mignon, G., Pitel Frédérique, Leroux Sophie, Abasht, Behnam, Douaire, M., Guernec, Gregory, Douaire, Madeleine, Madeleine Douaire, Guernec Gregory, Demeure, Olivier, Abasht Behnam, Guernec, G., Le Roy Pascale   +39 more
core   +1 more source

BioMercator : A complete framework to integrate QTL, meta-QTL, genome annotation and genome-wide association studies.

, 2015
International audienceCompilation of genetic maps combined to QTL meta-analysis has proven to be a powerful approach contributing to the identification of candidate genes underlying quantitative traits. One of the most interesting properties of meta-QTL (
Sosnowski, Olivier, Joets, Johann, Ait-Braham, Lydia, de Oliveira, Yannick   +3 more
core   +2 more sources

Large-Scale Data Integration Reveals Colocalization of Gene Functional Groups with Meta-QTL for Multiple Disease Resistance in Barley

Molecular Plant-Microbe Interactions, 2011
Race-nonspecific and durable resistance of plant genotypes to major pathogens is highly relevant for yield stability and sustainable crop production but difficult to handle in practice due to its polygenic inheritance by quantitative trait loci (QTL). As
Patrick Schweizer, Nils Stein
doaj   +1 more source

GABAergic Network Dysregulation in Alcohol Use Disorder: Receptor–Transporter Interactions Driving the Transition From Goal‐Directed to Compulsive Behaviour

Addiction Biology, Volume 31, Issue 11, November 2026.
Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda, Nathan Jones, Humza Haroon, Doo‐Sup Choi   +3 more
wiley   +1 more source

Uncovering key genomic regions for agronomical traits and stress tolerance in sorghum [Sorghum bicolor (L.) Moench] through meta-QTL analysis

Sorghum [Sorghum bicolor (L.) Moench] is a crucial food and fodder crop worldwide, particularly significant in the current era of climate change due to its capacity to withstand abiotic stresses such as drought and heat.
Eerapagula, Ramesh, Bhutia, K. L., Verma, Shruti, Sahni, Sangita, Jha, Sonam, Rangari, Sagar Krushnaji, Sharma, V. K., Naik, Yogesh Dashrath, Mishra, Soumya, Prasad, Bishun Deo, Mahato, Ajay Kumar, Mane, Rushikesh Sanjay, Thudi, Mahendar, Quaiyum, Zeba   +13 more
core   +1 more source

Comparison of analyses of the QTLMAS XIII common dataset. II: QTL analysis [PDF]

, 2010
Background - Five participants of the QTL-MAS 2009 workshop applied QTL analyses to the workshop common data set which contained a time-related trait: cumulative yield.
Calus, M.P.L., John Bastiaansen, Coster, A., Albart Coster, Bastiaansen, J.W.M., Marco Bink, Bink, M.C.A.M., Maliepaard, C.A., Chris Maliepaard, Mario Calus   +9 more
core   +1 more source

Genome-wide Association Studies for Female Fertility Traits in Chinese and Nordic Holsteins

Scientific Reports, 2017
Reduced female fertility could cause considerable economic loss and has become a worldwide problem in the modern dairy industry. The objective of this study was to detect quantitative trait loci (QTL) for female fertility traits in Chinese and Nordic ...
Aoxing Liu, Yachun Wang, Goutam Sahana, Qin Zhang, Lin Liu, Mogens Sandø Lund, Guosheng Su   +6 more
doaj   +1 more source

Integrated Multi‐Omics Analyses Reveal Causal DNA Methylation‐Breast Cancer Associations Mediated by Plasma Proteins

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Although aberrant DNA methylation is implicated in breast cancer (BC) pathogenesis, establishing causality is difficult and the downstream mediators are unclear. We investigated the causal role of blood DNA methylation and its proteomic mediators.
Wei Wang, Ziye Cheng, Ruidong Liu, Xufeng Cheng, Hanghang Chen   +4 more
wiley   +1 more source

A mixed model QTL analysis for sugarcane multiple-harvest-location trial data [PDF]

, 2011
Sugarcane-breeding programs take at least 12 years to develop new commercial cultivars. Molecular markers offer a possibility to study the genetic architecture of quantitative traits in sugarcane, and they may be used in marker-assisted selection to ...
Pinto, L. R., Oliveira, K. M., Margarido, G. R. A., Pinto L.R., Mollinari M., M. Malosetti, Eeuwijk, F.A., van, Oliveira K.M., Pastina, M. M., R. Gazaffi, Pastina M.M., van Eeuwijk F.A., Mollinari, M., Malosetti M., Garcia A.A.F., Gazaffi R., A. A. F. Garcia, K. M. Oliveira, Souza, A. P., M. Mollinari, G. R. A. Margarido, Gazaffi, R., Souza A.P., Pastina, M.M., F. A. van Eeuwijk, Oliveira, K.M., L. R. Pinto, Malosetti, M., Margarido, G.R.A., Pinto, L.R., Garcia, A.A.F., Margarido G.R.A., Garcia, A. A. F., Souza, A.P., van Eeuwijk, F. A., M. M. Pastina, A. P. Souza   +36 more
core   +1 more source