Results 71 to 80 of about 1,153,004 (118)

Comparative Genome‐Wide Association Studies of Metabolites and Grain‐Related Traits in Common Wheat

open access: yesPlant Biotechnology Journal, Volume 24, Issue 11, Page 5911-5926, November 2026.
ABSTRACT The metabolome is highly diverse and the closest layer to phenotype; therefore, it is commonly regarded as a bridge between the genome and phenome in plants. Here, we performed large‐scale metabolome analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and 33 grain‐related traits in a diverse panel of natural accessions and
Guoguo Lv   +11 more
wiley   +1 more source

Integrative omics in translational pharmacology: A target‐credibility framework for biomarker‐guided therapy

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Integrative omics strengthens target credibility by combining causal, functional, pharmacological and tissue‐context evidence. Go, refine and stop decisions convert multi‐omics findings into actionable translational choices. Biomarker readiness requires analytical validity, clinical validity, utility and implementation within a defined context of use ...
Ruba Altahla   +7 more
wiley   +1 more source

Deciphering transcriptome complexity via long‐read sequencing

open access: yesiMeta, Volume 5, Issue 5, October 2026.
Long‐read sequencing is transforming transcriptomics from gene‐level quantification to isoform‐resolved interpretation by directly resolving full‐length transcript structures, transcription in repetitive regions, and linked molecular features. This review provides an end‐to‐end roadmap covering sequencing platforms, library preparation strategies ...
Chuwen Xu   +21 more
wiley   +1 more source

Meta-analysis of major QTL for abiotic stress tolerance in barley and implications for barley breeding

open access: yes, 2017
Drought, salinity and waterlogging are three major abiotic stresses limiting barley yield worldwide. Breeding for abiotic stress-tolerant crops has drawn increased attention, and a large number of quantitative trait loci (QTL) for drought, salinity, and ...
Meixue Zhou (14753947)   +4 more
core  

Dissection of Leaf Angle Variation in Maize through Genetic Mapping and Meta-Analysis

open access: yesThe Plant Genome, 2019
Maize ( L.) hybrids have transitioned to upright leaf angles (LAs) over the last 50 yr as maize yields and planting densities increased concurrently.
Matthew J. Dzievit   +2 more
doaj   +1 more source

Genetic Regulation of DNA Methylation and Its Mediating Role in Blood Pressure: A Genome‐Wide Twin Study

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Using 1056 Chinese twins, we estimated DNA methylation heritability (mean h2 = 18.3%) and genetic correlations with blood pressure. Association analyses identified 914 SBP‐related and 624 DBP‐related CpGs, with attenuation within monozygotic pairs. Integrating mQTL, GWAS, eQTL, and pQTL data identified bidirectional CpG–blood pressure relationships and
Xuanming Hong   +17 more
wiley   +1 more source

Details of mapping studies used for popping traits in meta-QTL analysis.

open access: yes, 2021
Details of mapping studies used for popping traits in meta-QTL analysis.
Sujay Rakshit (10098774)   +4 more
core   +1 more source

Meta-analysis of sequence-based association studies across three cattle breeds reveals 25 QTL for fat and protein percentages in milk at nucleotide resolution

open access: yesBMC Genomics, 2017
Background Genotyping and whole-genome sequencing data have been generated for hundreds of thousands of cattle. International consortia used these data to compile imputation reference panels that facilitate the imputation of sequence variant genotypes ...
Hubert Pausch   +5 more
doaj   +1 more source

Adiponectin and Pulmonary Hypertension Risk: Mendelian Randomization and Receptor‐Side Genetic Evidence

open access: yesPulmonary Circulation, Volume 16, Issue 4, October 2026.
ABSTRACT Circulating adiponectin is generally considered metabolically protective, but higher levels have been associated with adverse outcomes in some cardiovascular diseases and states of high disease burden, a pattern referred to as the adiponectin paradox.
Ruixian Wu   +5 more
wiley   +1 more source

Efficient QTL detection for nonhost resistance in wild lettuce: backcross inbred lines versus F2 [PDF]

open access: yes, 2008
In plants, several population types [F2, recombinant inbred lines, backcross inbred lines (BILs), etc.] are used for quantitative trait locus (QTL) analyses.
Stam, P.   +7 more
core   +1 more source

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