Results 21 to 30 of about 1,774 (249)
Antioxidants, 2021 Atherosclerosis is the predominant pathology associated to premature deaths due to cardiovascular disease. However, early intervention based on a personalized diagnosis of cardiovascular risk is very limited.
Aranzazu Santiago-Hernandez +9 more
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Deregulated Metabolic Pathways in Ovarian Cancer: Cause and Consequence
Metabolites, 2023 Ovarian cancers are tumors that originate from the different cells of the ovary and account for almost 4% of all the cancers in women globally. More than 30 types of tumors have been identified based on the cellular origins. Epithelial ovarian cancer (EOC) is the most common and lethal type of ovarian cancer which can be further divided into high-grade
Roopak Murali +7 more
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Muscle and Bone Impairment in Infantile Nephropathic Cystinosis: New Concepts
Cells, 2022 Cystinosis Metabolic Bone Disease (CMBD) has emerged during the last decade as a well-recognized, long-term complication in patients suffering from infantile nephropathic cystinosis (INC), resulting in significant morbidity and impaired quality of life ...
Dieter Haffner +3 more
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Molecules, 2022 Pendimethalin-based herbicides are used worldwide for pre-emergence selective control of annual grasses and weeds in croplands. The endurance of herbicides residues in the environment has an impact on the soil biodiversity and fertility, also affecting ...
Donatella Aiello +5 more
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SteatoNet: the first integrated human metabolic model with multi-layered regulation to investigate liver-associated pathologies. [PDF]
PLoS Computational Biology, 2014 Current state-of-the-art mathematical models to investigate complex biological processes, in particular liver-associated pathologies, have limited expansiveness, flexibility, representation of integrated regulation and rely on the availability of ...
Adviti Naik +2 more
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Biomarkers of stress-mediated metabolic deregulation in diabetes mellitus [PDF]
Diabetes Research and Clinical Practice, 2017 Cette revue illustre la relation entre le stress oxydatif et nitratif et le diabète sucré et ses complications. Ceci est d'un intérêt considérable car le diabète sucré est une maladie métabolique systémique à vie qui peut survenir pendant l'enfance ou l'âge adulte et affecte non seulement une triade d'insuline des cellules des îlots pancréatiques, d ...
Dina Johar, Larry Bernstein
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Immunometabolism features of metabolic deregulation and cancer
Journal of Cellular and Molecular Medicine, 2018 AbstractImmunometabolism is a branch dealing at the interface of immune functionalities and metabolic regulations. Considered as a bidirectional trafficking, metabolic contents and their precursors bring a considerable change in immune cells signal transductions which as a result affect the metabolic organs and states as an implication. Lipid metabolic
Xue Wang +4 more
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Deregulation of Lipid Metabolism: The Critical Factors in Ovarian Cancer [PDF]
Frontiers in Oncology, 2020 Ovarian cancer is one of the most malignant gynecological cancers around the world. In spite of multiple treatment options, the five-year survival rate is still very low. Several metabolism alterations are described as a hallmark in cancers, but alterations of lipid metabolism in ovarian cancer have been paid less attention.
Zhaodong Ji +14 more
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Molecular interactions between NAFLD and xenobiotic metabolism
Frontiers in Genetics, 2013 Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, is a complex multifactorial disease characterised by metabolic deregulations that include accumulation of lipids in the liver, lipotoxicity and insulin ...
Adviti eNaik +3 more
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Formation of benign tumors by stem cell deregulation.
PLoS Genetics, 2022 Within living organisms, stem cells respond to various cues, including to niche signals and growth factors. Niche signals originate from the stem cell's microenvironment and promote the undifferentiated state by preventing differentiation, allowing for ...
Matthieu Valet, Patrick Narbonne
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