Results 131 to 140 of about 12,548,139 (260)

Advancing the Development of the China-SCO Cooperation Center for Metabolic Diseases to Foster a Global Community of Health for All. [PDF]

J Diabetes
Ning G.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The burden of metabolic diseases in the Arab region, 1990-2021. [PDF]

Ther Adv Endocrinol Metab
Pan Z, Fouad Y, Abaalkhail F, Al Hassani A, Altarrah MY, Derbala M, Abdulla M, Tahiri M, Al-Busafi SA, Alkhalidi N, Hotayt B, Al-Awadhi S, Soliman R, Shiha G, Sanai FM, Eslam M.   +15 more
europepmc   +1 more source

Metabolism and skin diseases [PDF]

Reviews in Endocrine and Metabolic Disorders, 2016
Zouboulis, C.C., Stratakis, C.A., Chrousos, G.P., Koch, C.A.   +3 more
openaire   +3 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Network Toxicology Reveals the Mechanisms of the Plasticizer Metabolite MECPP in Metabolic Diseases. [PDF]

Int J Mol Sci
Qiu J, Cheng C, Jiang B, Yang D, Peng H.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Editorial: Micronutrients and metabolic diseases - volume II. [PDF]

Front Nutr
Li J, Yang A, Luo Y, An P.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Emerging Insights into the Liver-Pancreas Axis: A Central Hub in the Pathogenesis of Diabetes and Metabolic Diseases. [PDF]

Biomolecules
Dai H, Zhang Z.
europepmc   +1 more source