Results 181 to 190 of about 623,308 (344)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Bio-engineering of in-vitro vascularized 3D tissue models in context of metabolic syndrome and obesity [PDF]
Marder, Maren +2 more
openalex
Metabolic and Process Engineering of Pichia Pastoris for the Production of Value-added Products
, 2017 Zhiliang Yang
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FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Metabolic engineering enables <i>Escherichia coli</i> to grow on 1,3-propanediol. [PDF]
Synth Syst BiotechnolPoon NY, Sinskey AJ, Zhou K.
europepmc +1 more source
Metabolic Engineering, Medicinal Resources [PDF]
, 2008 El-Halawany Ali Mahmoud +4 more
core +1 more source
Metabolic engineering of C. glutamicum for amino acid production improvement
, 2000 Mattheos Koffas
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The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Metabolic Engineering Strategy for <i>Bacillus subtilis</i> Producing MK-7. [PDF]
FoodsWu S +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source