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Systems Metabolic Engineering of Industrial Microorganisms
Microorganisms, 2023 The green and sustainable production of chemicals, materials, fuels, food, and pharmaceuticals has become a key solution to the global energy and environmental crisis [...]
Xueqin Lv +3 more
doaj +1 more source
Metabolic Engineering of Corynebacterium glutamicum for Methanol Metabolism [PDF]
Applied and Environmental Microbiology, 2015 ABSTRACT Methanol is already an important carbon feedstock in the chemical industry, but it has found only limited application in biotechnological production processes. This can be mostly attributed to the inability of most microbial platform organisms to utilize methanol as a carbon and energy source.
Sabrina Witthoff +6 more
openaire +3 more sources
Why Optimal States Recruit Fewer Reactions in Metabolic Networks [PDF]
Discret. Contin. Dyn. Syst. A. 32(8), 2937 (2012), 2012 The metabolic network of a living cell involves several hundreds or thousands of interconnected biochemical reactions. Previous research has shown that under realistic conditions only a fraction of these reactions is concurrently active in any given cell.
arxiv +1 more source
Metabolic engineering of roseoflavin-overproducing microorganisms
Microbial Cell Factories, 2019 Background Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus.
Rodrigo Mora-Lugo +2 more
doaj +1 more source
A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2
iScience, 2020 Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy +6 more
doaj
Dynamic metabolic control: towards precision engineering of metabolism [PDF]
Journal of Industrial Microbiology and Biotechnology, 2018 Abstract Advances in metabolic engineering have led to the synthesis of a wide variety of valuable chemicals in microorganisms. The key to commercializing these processes is the improvement of titer, productivity, yield, and robustness.
Liu, D +4 more
openaire +5 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Key applications of plant metabolic engineering. [PDF]
PLoS Biology, 2014 Great strides have been made in plant metabolic engineering over the last two decades, with notable success stories including Golden rice. Here, we discuss the field's progress in addressing four long-standing challenges: creating plants that satisfy ...
Warren Lau +3 more
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Genetic and metabolic engineering in diatoms [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017 Diatoms have attracted considerable attention due to their success in diverse environmental conditions, which probably is a consequence of their complex origins. Studies of their metabolism will provide insight into their adaptation capacity and are a prerequisite for metabolic engineering.
Weichao Huang, Fayza Daboussi
openaire +6 more sources
Evolutionary multiobjective algorithms for in silico metabolic engineering [PDF]
, 2008 The aims of this Metabolic Engineering conference are to provide a forum for academic and industrial researchers in the field; to bring together the different scientific disciplines that contribute to the design, analysis and optimization of metabolic ...
Ferreira, E. C. +4 more
core +2 more sources