Specific inhibition of glutamine synthase involved in the metabolic pathway of amino acids is associated with anti-arthritic effects of sinomenine hydrochloride. [PDF]
Li G +7 more
europepmc +1 more source
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
Engineering Sanghuangporus sanghuang for enhanced (-)-aristolone production via metabolic pathway optimization and terpene synthase engineering. [PDF]
Li Y +8 more
europepmc +1 more source
A Study on the Metabolic Pathway of Pregnancy Specific β<SUB>1</SUB> -Glycoprotein (SP<SUB>1</SUB>)
Masazumi ITO
openalex +2 more sources
Metabolic engineering of the Lactococcus lactis diacetyl pathway [PDF]
Michael J. Gasson +3 more
openalex +1 more source
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
The human gut microbiome and its metabolic pathway dynamics before and during HIV antiretroviral therapy. [PDF]
Dolo O +17 more
europepmc +1 more source
Development of the ornithine cycle in rat liver: Zonation of a metabolic pathway [PDF]
Maria A. Dingemanse +5 more
openalex +1 more source
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Rhein Inhibits Microglia-Mediated Neuroinflammation and Neuronal Damage of Alzheimer's Disease via Regulating the Glutamine-Aspartate-Arginine-NO Metabolic Pathway. [PDF]
Chi B +6 more
europepmc +1 more source

